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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 37

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Neurotrophin Responsiveness of Sympathetic Neurons Is Regulated by Rapid Mobilization of the p75 Receptor to the Cell Surface through TrkA Activation of Arf6.
Hickman FE, Stanley EM, Carter BD
(2018) J Neurosci 38: 5606-5619
MeSH Terms: ADP-Ribosylation Factor 6, ADP-Ribosylation Factors, Animals, Nerve Tissue Proteins, Neurogenesis, Neurons, Neurotrophin 3, Rats, Rats, Sprague-Dawley, Receptor, trkA, Receptors, Growth Factor, Receptors, Nerve Growth Factor, Sympathetic Nervous System
Added April 4, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT and MEK/ERK signaling in breast cancer.
Dillon LM, Bean JR, Yang W, Shee K, Symonds LK, Balko JM, McDonald WH, Liu S, Gonzalez-Angulo AM, Mills GB, Arteaga CL, Miller TW
(2015) Oncogene 34: 3968-76
MeSH Terms: Animals, Breast Neoplasms, Cell Survival, Feedback, Physiological, Female, Guanine Nucleotide Exchange Factors, Humans, MAP Kinase Signaling System, MCF-7 Cells, Mice, Inbred NOD, Mice, SCID, Mutation, Neoplasm Transplantation, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Receptors, Growth Factor, rac GTP-Binding Proteins
Added October 21, 2014
0 Communities
2 Members
0 Resources
17 MeSH Terms
A role for the p75 neurotrophin receptor in axonal degeneration and apoptosis induced by oxidative stress.
Kraemer BR, Snow JP, Vollbrecht P, Pathak A, Valentine WM, Deutch AY, Carter BD
(2014) J Biol Chem 289: 21205-16
MeSH Terms: Animals, Apoptosis, Axons, Cells, Cultured, Mice, Mice, Inbred C57BL, Nerve Tissue Proteins, Oxidative Stress, Rats, Rats, Sprague-Dawley, Receptors, Growth Factor, Receptors, Nerve Growth Factor, Visual Field Tests
Added January 22, 2015
0 Communities
3 Members
0 Resources
13 MeSH Terms
The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release.
Escudero CA, Lazo OM, Galleguillos C, Parraguez JI, Lopez-Verrilli MA, Cabeza C, Leon L, Saeed U, Retamal C, Gonzalez A, Marzolo MP, Carter BD, Court FA, Bronfman FC
(2014) J Cell Sci 127: 1966-79
MeSH Terms: Animals, Endosomes, Exosomes, Lysosomes, Microscopy, Fluorescence, Multivesicular Bodies, Nerve Tissue Proteins, Neurons, PC12 Cells, RNA Interference, Rats, Receptors, Growth Factor, Receptors, Nerve Growth Factor
Added March 17, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Isolation and characterization of node/notochord-like cells from mouse embryonic stem cells.
Winzi MK, Hyttel P, Dale JK, Serup P
(2011) Stem Cells Dev 20: 1817-27
MeSH Terms: Animals, Antigens, Differentiation, Benzamides, Cell Differentiation, Cell Line, Cell Proliferation, Chick Embryo, Dioxoles, Embryonic Stem Cells, Green Fluorescent Proteins, Hepatocyte Nuclear Factor 3-beta, Homeodomain Proteins, Intercellular Signaling Peptides and Proteins, Mice, Notochord, Organizers, Embryonic, Peptide Hormones, Pyrroles, Receptors, Growth Factor, Recombinant Fusion Proteins, Signal Transduction, Tissue Culture Techniques, Transplantation, Heterologous
Added May 13, 2013
0 Communities
0 Members
1 Resources
23 MeSH Terms
Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers.
Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PI, Verveer PJ, Carter BD, Ibáñez CF
(2009) Neuron 62: 72-83
MeSH Terms: Animals, Animals, Newborn, Binding Sites, Cell Death, Cells, Cultured, Chlorocebus aethiops, Cysteine, Green Fluorescent Proteins, Humans, Membrane Proteins, Mice, Mutation, NF-kappa B, Nerve Growth Factor, Nerve Tissue Proteins, Neurons, Oligopeptides, Protein Binding, Protein Conformation, Protein Multimerization, RNA, Small Interfering, Rats, Receptor, Nerve Growth Factor, Receptors, Growth Factor, Receptors, Nerve Growth Factor, Signal Transduction, Superior Cervical Ganglion, Transfection, rhoA GTP-Binding Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
29 MeSH Terms
Genetic evidence implicating multiple genes in the MET receptor tyrosine kinase pathway in autism spectrum disorder.
Campbell DB, Li C, Sutcliffe JS, Persico AM, Levitt P
(2008) Autism Res 1: 159-68
MeSH Terms: Alleles, Autistic Disorder, Exons, Genotype, Hepatocyte Growth Factor, Humans, Linkage Disequilibrium, Plasminogen Activator Inhibitor 1, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-met, Receptors, Growth Factor, Receptors, Urokinase Plasminogen Activator, Signal Transduction
Added February 20, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Distinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditions.
Campbell DB, Buie TM, Winter H, Bauman M, Sutcliffe JS, Perrin JM, Levitt P
(2009) Pediatrics 123: 1018-24
MeSH Terms: Alleles, Autistic Disorder, Child, Comorbidity, Female, Gastrointestinal Diseases, Genetic Predisposition to Disease, Genotype, Humans, Linkage Disequilibrium, Male, Phenotype, Promoter Regions, Genetic, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-met, Receptors, Growth Factor, Risk Factors, Signal Transduction
Added February 20, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Disruption of cerebral cortex MET signaling in autism spectrum disorder.
Campbell DB, D'Oronzio R, Garbett K, Ebert PJ, Mirnics K, Levitt P, Persico AM
(2007) Ann Neurol 62: 243-50
MeSH Terms: Autistic Disorder, Blotting, Western, Cerebral Cortex, Child, DNA, Databases, Factual, Female, Genotype, Hepatocyte Growth Factor, Humans, Male, Nerve Net, Oligonucleotide Array Sequence Analysis, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-met, RNA, Messenger, Receptor Protein-Tyrosine Kinases, Receptors, Growth Factor, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Temporal Lobe, Tissue Banks, Transcription, Genetic
Added May 19, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
A genetic variant that disrupts MET transcription is associated with autism.
Campbell DB, Sutcliffe JS, Ebert PJ, Militerni R, Bravaccio C, Trillo S, Elia M, Schneider C, Melmed R, Sacco R, Persico AM, Levitt P
(2006) Proc Natl Acad Sci U S A 103: 16834-9
MeSH Terms: Alleles, Autistic Disorder, Base Sequence, Case-Control Studies, Chromosome Mapping, Chromosomes, Human, Pair 7, DNA, Female, Genetic Predisposition to Disease, Genetic Variation, Genotype, Humans, Linkage Disequilibrium, Male, Polymorphism, Single Nucleotide, Promoter Regions, Genetic, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-met, Receptors, Growth Factor, Transcription Factors, Transcription, Genetic
Added February 20, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms