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Results: 1 to 10 of 138

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A compendium of G-protein-coupled receptors and cyclic nucleotide regulation of adipose tissue metabolism and energy expenditure.
Ceddia RP, Collins S
(2020) Clin Sci (Lond) 134: 473-512
MeSH Terms: Adipocytes, Adipose Tissue, Animals, Diabetes Mellitus, Type 2, Energy Metabolism, Humans, Lipolysis, Nucleotides, Cyclic, Receptors, G-Protein-Coupled, Signal Transduction
Added March 26, 2020
0 Communities
2 Members
0 Resources
10 MeSH Terms
Plethora of functions packed into 45 kDa arrestins: biological implications and possible therapeutic strategies.
Gurevich VV, Gurevich EV
(2019) Cell Mol Life Sci 76: 4413-4421
MeSH Terms: Animals, Arrestins, Humans, Receptors, G-Protein-Coupled, Signal Transduction
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Disabling the Gβγ-SNARE interaction disrupts GPCR-mediated presynaptic inhibition, leading to physiological and behavioral phenotypes.
Zurawski Z, Thompson Gray AD, Brady LJ, Page B, Church E, Harris NA, Dohn MR, Yim YY, Hyde K, Mortlock DP, Jones CK, Winder DG, Alford S, Hamm HE
(2019) Sci Signal 12:
MeSH Terms: Animals, Calcium, Exocytosis, GTP-Binding Protein alpha Subunits, Gi-Go, GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, Mice, Inbred C57BL, Mice, Inbred DBA, Mice, Knockout, Neural Inhibition, Phenotype, Protein Binding, Receptors, G-Protein-Coupled, Synaptic Transmission, Synaptosomal-Associated Protein 25
Added February 22, 2019
1 Communities
3 Members
0 Resources
15 MeSH Terms
Systemic bile acids induce insulin resistance in a TGR5-independent manner.
Syring KE, Cyphert TJ, Beck TC, Flynn CR, Mignemi NA, McGuinness OP
(2019) Am J Physiol Endocrinol Metab 316: E782-E793
MeSH Terms: Animals, Bile Acids and Salts, Cholagogues and Choleretics, Cholic Acids, Deoxycholic Acid, Gene Expression Profiling, Gluconeogenesis, Glucose Clamp Technique, Hep G2 Cells, Hepatocytes, Humans, Insulin Resistance, Liver, Mice, Mice, Knockout, Obesity, Primary Cell Culture, Receptors, G-Protein-Coupled, Taurocholic Acid
Added April 15, 2019
0 Communities
1 Members
0 Resources
19 MeSH Terms
The expanding roles and mechanisms of G protein-mediated presynaptic inhibition.
Zurawski Z, Yim YY, Alford S, Hamm HE
(2019) J Biol Chem 294: 1661-1670
MeSH Terms: Action Potentials, Biochemistry, History, 20th Century, History, 21st Century, Humans, Periodicals as Topic, Presynaptic Terminals, Receptors, G-Protein-Coupled, Synaptic Transmission
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
The structural basis of the arrestin binding to GPCRs.
Gurevich VV, Gurevich EV
(2019) Mol Cell Endocrinol 484: 34-41
MeSH Terms: Animals, Arrestin, Binding Sites, G-Protein-Coupled Receptor Kinases, Humans, Models, Molecular, Phosphorylation, Protein Binding, Protein Conformation, Protein Domains, Receptors, G-Protein-Coupled
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
α-Adrenergic Receptor Activation Decreases Parabrachial Nucleus Excitatory Drive onto BNST CRF Neurons and Reduces Their Activity .
Fetterly TL, Basu A, Nabit BP, Awad E, Williford KM, Centanni SW, Matthews RT, Silberman Y, Winder DG
(2019) J Neurosci 39: 472-484
MeSH Terms: Adrenergic alpha-2 Receptor Agonists, Animals, Corticotropin-Releasing Hormone, Female, Gene Expression, Genes, fos, Guanfacine, Male, Mice, Mice, Inbred C57BL, Neurons, Norepinephrine, Ovariectomy, Parabrachial Nucleus, Patch-Clamp Techniques, Protein Kinase C-delta, Receptors, Adrenergic, alpha-2, Receptors, G-Protein-Coupled, Restraint, Physical, Septal Nuclei, Stress, Psychological
Added March 26, 2019
0 Communities
1 Members
0 Resources
21 MeSH Terms
Role of Bile Acids and GLP-1 in Mediating the Metabolic Improvements of Bariatric Surgery.
Albaugh VL, Banan B, Antoun J, Xiong Y, Guo Y, Ping J, Alikhan M, Clements BA, Abumrad NN, Flynn CR
(2019) Gastroenterology 156: 1041-1051.e4
MeSH Terms: Anastomosis, Surgical, Animals, Anticholesteremic Agents, Bariatric Surgery, Bile Acids and Salts, Blood Glucose, Cholestyramine Resin, Diet, High-Fat, Gallbladder, Glucagon-Like Peptide 1, Glucagon-Like Peptide-1 Receptor, Glucose Tolerance Test, Ileum, Insulin Resistance, Intestines, Lymph, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Receptors, Cytoplasmic and Nuclear, Receptors, G-Protein-Coupled, Signal Transduction, Verrucomicrobia, Weight Loss
Added January 4, 2019
0 Communities
2 Members
0 Resources
25 MeSH Terms
A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension.
Hemnes AR, Rathinasabapathy A, Austin EA, Brittain EL, Carrier EJ, Chen X, Fessel JP, Fike CD, Fong P, Fortune N, Gerszten RE, Johnson JA, Kaplowitz M, Newman JH, Piana R, Pugh ME, Rice TW, Robbins IM, Wheeler L, Yu C, Loyd JE, West J
(2018) Eur Respir J 51:
MeSH Terms: Adult, Aged, Angiotensin-Converting Enzyme 2, Animals, Biomarkers, Cytokines, Female, Gene Expression, Humans, Hypertension, Pulmonary, Male, Middle Aged, Peptidyl-Dipeptidase A, Pilot Projects, Proof of Concept Study, Proto-Oncogene Proteins, Pulmonary Artery, Receptors, G-Protein-Coupled, Superoxide Dismutase, Swine, Vascular Resistance
Added March 26, 2019
0 Communities
3 Members
0 Resources
21 MeSH Terms
GPCRs and Signal Transducers: Interaction Stoichiometry.
Gurevich VV, Gurevich EV
(2018) Trends Pharmacol Sci 39: 672-684
MeSH Terms: Animals, Arrestins, GTP-Binding Proteins, Humans, Receptors, G-Protein-Coupled, Signal Transduction
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms