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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 16

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The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.
Ono K, Karolak MR, Ndong Jde L, Wang W, Yang X, Elefteriou F
(2013) Hum Mol Genet 22: 3048-62
MeSH Terms: Animals, Apoptosis, Cell Proliferation, Chondrocytes, Chondrogenesis, Extracellular Signal-Regulated MAP Kinases, Gene Expression, Growth Plate, Mice, Knockout, Neurofibromin 1, Osteogenesis, Receptors, Fibroblast Growth Factor, Signal Transduction
Added November 14, 2013
0 Communities
3 Members
0 Resources
13 MeSH Terms
Fibroblast growth factor (FGF) and FGF receptor-mediated autocrine signaling in non-small-cell lung cancer cells.
Marek L, Ware KE, Fritzsche A, Hercule P, Helton WR, Smith JE, McDermott LA, Coldren CD, Nemenoff RA, Merrick DT, Helfrich BA, Bunn PA, Heasley LE
(2009) Mol Pharmacol 75: 196-207
MeSH Terms: Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Fibroblast Growth Factors, Humans, Lung Neoplasms, RNA, Small Interfering, Receptors, Fibroblast Growth Factor, Signal Transduction
Added November 17, 2011
0 Communities
1 Members
0 Resources
8 MeSH Terms
Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice.
Freeman KW, Welm BE, Gangula RD, Rosen JM, Ittmann M, Greenberg NM, Spencer DM
(2003) Cancer Res 63: 8256-63
MeSH Terms: Animals, Cell Division, Disease Progression, MAP Kinase Signaling System, Male, Mice, Mice, Transgenic, Neovascularization, Pathologic, Prostatic Hyperplasia, Prostatic Intraepithelial Neoplasia, Prostatic Neoplasms, Receptor Protein-Tyrosine Kinases, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Fibroblast Growth Factor, Type 2, Receptors, Fibroblast Growth Factor, Transgenes
Added April 7, 2010
0 Communities
1 Members
0 Resources
16 MeSH Terms
Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation.
Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, Ittmann M, Greenberg NM, Spencer DM
(2003) Cancer Res 63: 6237-43
MeSH Terms: Adenocarcinoma, Animals, Apoptosis, Cell Division, Cell Line, Tumor, Enzyme Activation, Gene Expression Regulation, Neoplastic, Male, Mice, Mitogen-Activated Protein Kinase Kinases, Neoplasm Transplantation, Osteopontin, Phosphorylation, Prostatic Neoplasms, Receptor Protein-Tyrosine Kinases, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Fibroblast Growth Factor, Type 2, Receptors, Fibroblast Growth Factor, Sialoglycoproteins, Signal Transduction, Transfection, Up-Regulation
Added April 7, 2010
0 Communities
1 Members
0 Resources
22 MeSH Terms
In vivo inhibition of keratinocyte growth factor receptor expression by estrogen and antagonism by progesterone in the mouse mammary gland.
Imagawa W, Pedchenko VK
(2001) J Endocrinol 171: 319-27
MeSH Terms: Analysis of Variance, Animals, DNA, Dose-Response Relationship, Drug, Drug Synergism, Estradiol, Female, Gene Expression, Mammary Glands, Animal, Mice, Mice, Inbred BALB C, Progesterone, RNA, Messenger, Receptor, Fibroblast Growth Factor, Type 2, Receptors, Fibroblast Growth Factor, Time Factors
Added August 27, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity.
Schroeder MC, Hamby JM, Connolly CJ, Grohar PJ, Winters RT, Barvian MR, Moore CW, Boushelle SL, Crean SM, Kraker AJ, Driscoll DL, Vincent PW, Elliott WL, Lu GH, Batley BL, Dahring TK, Major TC, Panek RL, Doherty AM, Showalter HD
(2001) J Med Chem 44: 1915-26
MeSH Terms: 3T3 Cells, Animals, Antineoplastic Agents, CSK Tyrosine-Protein Kinase, Cell Division, Colonic Neoplasms, Enzyme Inhibitors, ErbB Receptors, Glioma, Humans, Indicators and Reagents, Kinetics, Mice, Molecular Conformation, Molecular Structure, Phosphorylation, Protein-Tyrosine Kinases, Pyrimidines, Rats, Receptors, Fibroblast Growth Factor, Receptors, Platelet-Derived Growth Factor, Recombinant Proteins, Structure-Activity Relationship, Transfection, Tumor Cells, Cultured, Urea, src-Family Kinases
Added March 5, 2014
0 Communities
1 Members
0 Resources
27 MeSH Terms
Pattern of expression of the KGF receptor and its ligands KGF and FGF-10 during postnatal mouse mammary gland development.
Pedchenko VK, Imagawa W
(2000) Mol Reprod Dev 56: 441-7
MeSH Terms: Animals, DNA Primers, Female, Fibroblast Growth Factor 10, Fibroblast Growth Factor 7, Fibroblast Growth Factors, Gene Expression, Growth Substances, Lactation, Ligands, Mammary Glands, Animal, Mice, Mice, Inbred BALB C, Pregnancy, RNA, Messenger, Receptor, Fibroblast Growth Factor, Type 2, Receptors, Fibroblast Growth Factor, Receptors, Growth Factor, Stromal Cells, Weaning
Added August 27, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms
Attenuation and loss of hormonal modulation of KGF (FGF-7)/KGF receptor expression and mitogenesis during mammary tumor progression.
Imagawa W, Pedchenko VK, Helber J, Xing C
(2000) J Cell Physiol 184: 222-8
MeSH Terms: Animals, Cell Transformation, Neoplastic, Female, Fibroblast Growth Factor 10, Fibroblast Growth Factor 7, Fibroblast Growth Factors, Growth Substances, Humans, Keratinocytes, Mammary Glands, Animal, Mammary Neoplasms, Experimental, Mice, Mitogens, Pregnancy, Progesterone, RNA, Messenger, Receptor, Fibroblast Growth Factor, Type 2, Receptors, Fibroblast Growth Factor, Receptors, Growth Factor, Tumor Cells, Cultured
Added August 27, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms
Fibroblast growth factor-1 (FGF-1) enhances IL-2 production and nuclear translocation of NF-kappaB in FGF receptor-bearing Jurkat T cells.
Byrd VM, Ballard DW, Miller GG, Thomas JW
(1999) J Immunol 162: 5853-9
MeSH Terms: Biological Transport, CD28 Antigens, Cell Nucleus, DNA-Binding Proteins, Drug Interactions, Fibroblast Growth Factor 1, Fibroblast Growth Factor 2, Humans, I-kappa B Proteins, Jurkat Cells, NF-KappaB Inhibitor alpha, NF-kappa B, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-rel, Receptor Protein-Tyrosine Kinases, Receptor, Fibroblast Growth Factor, Type 1, Receptors, Fibroblast Growth Factor, Response Elements, Signal Transduction, T-Lymphocytes, Transcription, Genetic
Added November 6, 2013
1 Communities
0 Members
0 Resources
21 MeSH Terms
A functional fibroblast growth factor-1 immunoglobulin fusion protein.
Dikov MM, Reich MB, Dworkin L, Thomas JW, Miller GG
(1998) J Biol Chem 273: 15811-7
MeSH Terms: 3T3 Cells, Animals, Antibodies, Anti-Idiotypic, DNA Replication, Diphtheria Toxin, Fibroblast Growth Factor 1, Flow Cytometry, Heparin, Humans, Immunoglobulin Fc Fragments, Jurkat Cells, Mice, Peptide Fragments, Phosphorylation, Receptor Protein-Tyrosine Kinases, Receptor, Fibroblast Growth Factor, Type 1, Receptors, Fibroblast Growth Factor, Recombinant Fusion Proteins, Staphylococcal Protein A, T-Lymphocytes, Tyrosine
Added November 6, 2013
1 Communities
1 Members
0 Resources
21 MeSH Terms