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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 89

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Metabolic Effects of Bile Acids: Potential Role in Bariatric Surgery.
Flynn CR, Albaugh VL, Abumrad NN
(2019) Cell Mol Gastroenterol Hepatol 8: 235-246
MeSH Terms: Akkermansia, Animals, Bariatric Surgery, Bile Acids and Salts, Humans, Insulin Resistance, Obesity, Morbid, Receptors, Cytoplasmic and Nuclear, Signal Transduction, Verrucomicrobia
Added December 17, 2019
0 Communities
1 Members
0 Resources
10 MeSH Terms
Role of Bile Acids and GLP-1 in Mediating the Metabolic Improvements of Bariatric Surgery.
Albaugh VL, Banan B, Antoun J, Xiong Y, Guo Y, Ping J, Alikhan M, Clements BA, Abumrad NN, Flynn CR
(2019) Gastroenterology 156: 1041-1051.e4
MeSH Terms: Anastomosis, Surgical, Animals, Anticholesteremic Agents, Bariatric Surgery, Bile Acids and Salts, Blood Glucose, Cholestyramine Resin, Diet, High-Fat, Gallbladder, Glucagon-Like Peptide 1, Glucagon-Like Peptide-1 Receptor, Glucose Tolerance Test, Ileum, Insulin Resistance, Intestines, Lymph, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Receptors, Cytoplasmic and Nuclear, Receptors, G-Protein-Coupled, Signal Transduction, Verrucomicrobia, Weight Loss
Added January 4, 2019
0 Communities
2 Members
0 Resources
25 MeSH Terms
Signaling through non-membrane nuclear phosphoinositide binding proteins in human health and disease.
Bryant JM, Blind RD
(2019) J Lipid Res 60: 299-311
MeSH Terms: Animals, Disease, Health, Humans, Phosphatidylinositols, Receptors, Cytoplasmic and Nuclear, Signal Transduction
Added January 19, 2019
0 Communities
1 Members
0 Resources
7 MeSH Terms
Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels.
Lyman KA, Han Y, Heuermann RJ, Cheng X, Kurz JE, Lyman RE, Van Veldhoven PP, Chetkovich DM
(2017) J Biol Chem 292: 17718-17730
MeSH Terms: Allosteric Regulation, Binding Sites, HEK293 Cells, Humans, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Protein Subunits, Receptors, Cytoplasmic and Nuclear
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Bile acids and bariatric surgery.
Albaugh VL, Banan B, Ajouz H, Abumrad NN, Flynn CR
(2017) Mol Aspects Med 56: 75-89
MeSH Terms: Animals, Bile Acids and Salts, Diabetes Mellitus, Type 2, Enterohepatic Circulation, Gastrectomy, Gastric Bypass, Gastrointestinal Microbiome, Gene Expression Regulation, Glucose, Homeostasis, Humans, Insulin Resistance, Obesity, Morbid, Receptors, Cytoplasmic and Nuclear, Receptors, G-Protein-Coupled, Rodentia, Signal Transduction
Added June 6, 2017
0 Communities
3 Members
0 Resources
17 MeSH Terms
Animal models suggest the TRIP8b-HCN interaction is a therapeutic target for major depressive disorder.
Lyman KA, Han Y, Chetkovich DM
(2017) Expert Opin Ther Targets 21: 235-237
MeSH Terms: Animals, Antidepressive Agents, Depressive Disorder, Major, Disease Models, Animal, Humans, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Receptors, Cytoplasmic and Nuclear
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b.
Han Y, Lyman KA, Clutter M, Schiltz GE, Ismail QA, Cheng X, Luan CH, Chetkovich DM
(2016) J Vis Exp :
MeSH Terms: Depressive Disorder, Major, Humans, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Membrane Proteins, Protein Binding, Receptors, Cytoplasmic and Nuclear, Small Molecule Libraries
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Phospholipid regulation of the nuclear receptor superfamily.
Crowder MK, Seacrist CD, Blind RD
(2017) Adv Biol Regul 63: 6-14
MeSH Terms: Animals, Gene Expression Regulation, Humans, Ligands, Mice, Models, Molecular, Phospholipids, Protein Binding, Receptors, Cytoplasmic and Nuclear, Signal Transduction, Transcription Factors, Transcription, Genetic
Added January 19, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket.
Sablin EP, Blind RD, Uthayaruban R, Chiu HJ, Deacon AM, Das D, Ingraham HA, Fletterick RJ
(2015) J Struct Biol 192: 342-348
MeSH Terms: Binding Sites, Crystallography, X-Ray, DAX-1 Orphan Nuclear Receptor, Humans, Models, Molecular, Phosphatidylinositols, Protein Binding, Protein Structure, Tertiary, Receptors, Cytoplasmic and Nuclear, Steroidogenic Factor 1
Added January 19, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Identification of Small-Molecule Inhibitors of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels.
Han Y, Lyman K, Clutter M, Schiltz GE, Ismail QA, Prados DB, Luan CH, Chetkovich DM
(2015) J Biomol Screen 20: 1124-31
MeSH Terms: Antidepressive Agents, Depressive Disorder, Major, Drug Evaluation, Preclinical, Escherichia coli, High-Throughput Screening Assays, Humans, Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels, Protein Binding, Receptors, Cytoplasmic and Nuclear
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms