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Results: 1 to 6 of 6

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Determination of the CD148-Interacting Region in Thrombospondin-1.
Takahashi K, Sumarriva K, Kim R, Jiang R, Brantley-Sieders DM, Chen J, Mernaugh RL, Takahashi T
(2016) PLoS One 11: e0154916
MeSH Terms: Animals, Binding Sites, Cell Proliferation, Cells, Cultured, Endothelial Cells, Gene Knockdown Techniques, Humans, Immunoblotting, Immunoprecipitation, Mice, Inbred C57BL, Neovascularization, Physiologic, Peptide Fragments, Protein Tyrosine Phosphatases, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Thrombospondin 1
Added April 26, 2017
0 Communities
1 Members
0 Resources
15 MeSH Terms
CD148 tyrosine phosphatase promotes cadherin cell adhesion.
Takahashi K, Matafonov A, Sumarriva K, Ito H, Lauhan C, Zemel D, Tsuboi N, Chen J, Reynolds A, Takahashi T
(2014) PLoS One 9: e112753
MeSH Terms: Cadherins, Cell Adhesion, Cell Line, Drosophila Proteins, Humans, Phosphorylation, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Tyrosine, beta Catenin, cdc42 GTP-Binding Protein, rac GTP-Binding Proteins, rhoA GTP-Binding Protein
Added February 12, 2015
1 Communities
2 Members
0 Resources
12 MeSH Terms
Thrombospondin-1 acts as a ligand for CD148 tyrosine phosphatase.
Takahashi K, Mernaugh RL, Friedman DB, Weller R, Tsuboi N, Yamashita H, Quaranta V, Takahashi T
(2012) Proc Natl Acad Sci U S A 109: 1985-90
MeSH Terms: Cell Proliferation, Extracellular Space, Gene Knockdown Techniques, Human Umbilical Vein Endothelial Cells, Humans, Kidney, Ligands, Microvessels, Protein Binding, Protein Structure, Tertiary, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Thrombospondin 1
Added August 27, 2013
3 Communities
2 Members
0 Resources
12 MeSH Terms
The tyrosine phosphatase CD148 interacts with the p85 regulatory subunit of phosphoinositide 3-kinase.
Tsuboi N, Utsunomiya T, Roberts RL, Ito H, Takahashi K, Noda M, Takahashi T
(2008) Biochem J 413: 193-200
MeSH Terms: Animals, CHO Cells, Cell Line, Cricetinae, Cricetulus, Humans, Mutation, Phosphatidylinositol 3-Kinases, Protein Binding, Protein Subunits, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Receptors, Platelet-Derived Growth Factor, Two-Hybrid System Techniques
Added August 27, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
A monoclonal antibody against CD148, a receptor-like tyrosine phosphatase, inhibits endothelial-cell growth and angiogenesis.
Takahashi T, Takahashi K, Mernaugh RL, Tsuboi N, Liu H, Daniel TO
(2006) Blood 108: 1234-42
MeSH Terms: Animals, Antibodies, Monoclonal, CHO Cells, Cornea, Cricetinae, Cricetulus, Endothelial Cells, Enzyme Inhibitors, G1 Phase, Humans, Inflammation, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Neoplasms, Neovascularization, Pathologic, Phosphorylation, Protein Processing, Post-Translational, Protein Structure, Tertiary, Protein Tyrosine Phosphatases, Proto-Oncogene Proteins c-met, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Resting Phase, Cell Cycle
Added August 27, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development.
Takahashi T, Takahashi K, St John PL, Fleming PA, Tomemori T, Watanabe T, Abrahamson DR, Drake CJ, Shirasawa T, Daniel TO
(2003) Mol Cell Biol 23: 1817-31
MeSH Terms: Alleles, Animals, Basic Helix-Loop-Helix Transcription Factors, Blotting, Northern, Blotting, Western, Catalysis, Catalytic Domain, Cell Division, Cytoplasm, DNA-Binding Proteins, Endothelium, Vascular, Ephrin-B2, Green Fluorescent Proteins, Homozygote, Kidney, Luminescent Proteins, Mice, Microscopy, Electron, Models, Genetic, Mutation, Myocardium, Platelet Endothelial Cell Adhesion Molecule-1, Precipitin Tests, Protein Tyrosine Phosphatases, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, Receptor, TIE-2, Receptor-Like Protein Tyrosine Phosphatases, Class 3, Recombinant Fusion Proteins, Recombination, Genetic, Reverse Transcriptase Polymerase Chain Reaction, T-Cell Acute Lymphocytic Leukemia Protein 1, Time Factors, Transcription Factors, Tyrosine, Vascular Endothelial Growth Factor Receptor-2
Added August 27, 2013
1 Communities
1 Members
0 Resources
36 MeSH Terms