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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 14

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The melanocortin-3 receptor is a pharmacological target for the regulation of anorexia.
Sweeney P, Bedenbaugh MN, Maldonado J, Pan P, Fowler K, Williams SY, Gimenez LE, Ghamari-Langroudi M, Downing G, Gui Y, Hadley CK, Joy ST, Mapp AK, Simerly RB, Cone RD
(2021) Sci Transl Med 13:
MeSH Terms: Animals, Anorexia, Feeding Behavior, Female, Hypothalamus, Male, Mice, Neurons, Receptor, Melanocortin, Type 3
Added April 30, 2021
1 Communities
0 Members
0 Resources
9 MeSH Terms
Regulation of energy rheostasis by the melanocortin-3 receptor.
Ghamari-Langroudi M, Cakir I, Lippert RN, Sweeney P, Litt MJ, Ellacott KLJ, Cone RD
(2018) Sci Adv 4: eaat0866
MeSH Terms: Animals, Energy Metabolism, Feeding Behavior, Female, Homeostasis, Inhibitory Postsynaptic Potentials, Male, Mice, Mice, Inbred C57BL, Neurons, Receptor, Melanocortin, Type 3
Added August 31, 2018
1 Communities
0 Members
0 Resources
11 MeSH Terms
Biased signaling in naturally occurring mutations in human melanocortin-3 receptor gene.
Yang F, Huang H, Tao YX
(2015) Int J Biol Sci 11: 423-33
MeSH Terms: Flow Cytometry, HEK293 Cells, Humans, MAP Kinase Signaling System, Mutagenesis, Site-Directed, Mutation, Receptor, Melanocortin, Type 3, Signal Transduction
Added January 29, 2016
0 Communities
1 Members
0 Resources
8 MeSH Terms
Functions of the DRY motif and intracellular loop 2 of human melanocortin 3 receptor.
Huang H, Tao YX
(2014) J Mol Endocrinol 53: 319-30
MeSH Terms: Amino Acid Sequence, Amino Acid Substitution, Cells, Cultured, HEK293 Cells, Humans, Ligands, Molecular Sequence Data, Mutagenesis, Site-Directed, Protein Binding, Protein Structure, Tertiary, Receptor, Melanocortin, Type 3, Structure-Activity Relationship, Transfection
Added January 29, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms
Gender-specific roles for the melanocortin-3 receptor in the regulation of the mesolimbic dopamine system in mice.
Lippert RN, Ellacott KL, Cone RD
(2014) Endocrinology 155: 1718-27
MeSH Terms: Animals, Appetitive Behavior, Behavior, Animal, Dopamine, Dopaminergic Neurons, Female, Food Preferences, Green Fluorescent Proteins, Homeostasis, Limbic System, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Mutant Strains, Mice, Transgenic, Nerve Tissue Proteins, Ovariectomy, Promoter Regions, Genetic, Receptor, Melanocortin, Type 3, Receptor, Melanocortin, Type 4, Sex Characteristics, Ventral Tegmental Area
Added May 27, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Melanocortin-3 receptor regulates the normal fasting response.
Renquist BJ, Murphy JG, Larson EA, Olsen D, Klein RF, Ellacott KL, Cone RD
(2012) Proc Natl Acad Sci U S A 109: E1489-98
MeSH Terms: Absorptiometry, Photon, Adipose Tissue, White, Adiposity, Adrenal Glands, Analysis of Variance, Animals, Biomechanical Phenomena, Blotting, Western, Body Composition, Corticosterone, Energy Metabolism, Fasting, Hypothalamo-Hypophyseal System, Immunohistochemistry, In Situ Hybridization, Lipolysis, Liver, Male, Mice, Mice, Knockout, Pituitary-Adrenal System, Real-Time Polymerase Chain Reaction, Receptor, Melanocortin, Type 3, Triglycerides
Added December 10, 2013
0 Communities
2 Members
0 Resources
24 MeSH Terms
Physiological roles of the melanocortin MC₃ receptor.
Renquist BJ, Lippert RN, Sebag JA, Ellacott KL, Cone RD
(2011) Eur J Pharmacol 660: 13-20
MeSH Terms: Amino Acid Sequence, Animals, Autoreceptors, Gene Expression Regulation, Humans, Molecular Sequence Data, Receptor, Melanocortin, Type 3
Added December 10, 2013
0 Communities
2 Members
0 Resources
7 MeSH Terms
Constitutive activity of neural melanocortin receptors.
Tao YX, Huang H, Wang ZQ, Yang F, Williams JN, Nikiforovich GV
(2010) Methods Enzymol 484: 267-79
MeSH Terms: Agouti Signaling Protein, Agouti-Related Protein, Cell Line, Humans, Receptor, Melanocortin, Type 3, Receptor, Melanocortin, Type 4, Receptors, Melanocortin
Added January 29, 2016
0 Communities
1 Members
0 Resources
7 MeSH Terms
The melanocortin-3 receptor is required for entrainment to meal intake.
Sutton GM, Perez-Tilve D, Nogueiras R, Fang J, Kim JK, Cone RD, Gimble JM, Tschöp MH, Butler AA
(2008) J Neurosci 28: 12946-55
MeSH Terms: ARNTL Transcription Factors, Animals, Appetite, Appetite Regulation, Basic Helix-Loop-Helix Transcription Factors, Brain, Cell Cycle Proteins, Cerebral Cortex, Circadian Rhythm, Feeding Behavior, Gene Expression Regulation, Hypothalamus, Mice, Mice, Inbred C57BL, Mice, Knockout, Motor Activity, Nerve Tissue Proteins, Nuclear Proteins, Period Circadian Proteins, Pro-Opiomelanocortin, Receptor, Melanocortin, Type 3, Transcription Factors, Wakefulness
Added December 10, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms
Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling.
Ellacott KL, Murphy JG, Marks DL, Cone RD
(2007) Endocrinology 148: 6186-94
MeSH Terms: Adipose Tissue, White, Adiposity, Animals, Chemokine CCL2, Dietary Fats, Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Inflammation, Insulin Resistance, Leptin, Liver, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Obesity, RNA, Messenger, Receptor, Melanocortin, Type 3, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Triglycerides, Tumor Necrosis Factor-alpha
Added December 10, 2013
1 Communities
2 Members
0 Resources
22 MeSH Terms