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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 134

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The Pan-Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA.
Disel U, Madison R, Abhishek K, Chung JH, Trabucco SE, Matos AO, Frampton GM, Albacker LA, Reddy V, Karadurmus N, Benson A, Webster J, Paydas S, Cabanillas R, Nangia C, Ozturk MA, Millis SZ, Pal SK, Wilky B, Sokol ES, Gay LM, Soman S, Ganesan S, Janeway K, Stephens PJ, Zhu VW, Ou SI, Lovly CM, Gounder M, Schrock AB, Ross JS, Miller VA, Klempner SJ, Ali SM
(2020) Oncologist 25: e39-e47
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Gene Amplification, Humans, Middle Aged, Neoplasms, Receptor Protein-Tyrosine Kinases, Receptor, Platelet-Derived Growth Factor alpha, Vascular Endothelial Growth Factor Receptor-2, Young Adult
Added September 10, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
Variable Response to ALK Inhibitors in NSCLC with a Novel MYT1L-ALK Fusion.
Tsou TC, Gowen K, Ali SM, Miller VA, Schrock AB, Lovly CM, Reckamp KL
(2019) J Thorac Oncol 14: e29-e30
MeSH Terms: Carcinoma, Non-Small-Cell Lung, Humans, Lung Neoplasms, Nerve Tissue Proteins, Protein Kinase Inhibitors, Receptor Protein-Tyrosine Kinases, Transcription Factors
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
AXL Mediates Esophageal Adenocarcinoma Cell Invasion through Regulation of Extracellular Acidification and Lysosome Trafficking.
Maacha S, Hong J, von Lersner A, Zijlstra A, Belkhiri A
(2018) Neoplasia 20: 1008-1022
MeSH Terms: Adenocarcinoma, Animals, Benzocycloheptenes, Biological Transport, Cathepsin B, Cell Line, Tumor, Chick Embryo, Chorioallantoic Membrane, Epithelial-Mesenchymal Transition, Esophageal Neoplasms, Gene Expression Regulation, Neoplastic, Humans, Hydrogen-Ion Concentration, Lactates, Lysosomes, Monocarboxylic Acid Transporters, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, Symporters, Triazoles
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Mechanisms of receptor tyrosine kinase activation in cancer.
Du Z, Lovly CM
(2018) Mol Cancer 17: 58
MeSH Terms: Animals, Cell Transformation, Neoplastic, Enzyme Activation, Gene Expression Regulation, Neoplastic, Humans, Ligands, Molecular Targeted Therapy, Mutation, Neoplasms, Phosphorylation, Protein Binding, Protein Interaction Domains and Motifs, Protein Kinase Inhibitors, Protein Multimerization, Receptor Protein-Tyrosine Kinases, Signal Transduction
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Managing Resistance to EFGR- and ALK-Targeted Therapies.
Lovly CM, Iyengar P, Gainor JF
(2017) Am Soc Clin Oncol Educ Book 37: 607-618
MeSH Terms: Anaplastic Lymphoma Kinase, Carcinoma, Non-Small-Cell Lung, Drug Resistance, Neoplasm, ErbB Receptors, Humans, Molecular Targeted Therapy, Mutation, Protein Kinase Inhibitors, Receptor Protein-Tyrosine Kinases
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculature.
Takahashi K, Kim R, Lauhan C, Park Y, Nguyen NG, Vestweber D, Dominguez MG, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gale NW, Takahashi T
(2017) PLoS One 12: e0177192
MeSH Terms: Animals, Endothelium, Vascular, Kidney, Mice, Phosphorylation, Promoter Regions, Genetic, Protein Tyrosine Phosphatases, Receptor Protein-Tyrosine Kinases
Added April 6, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Cracking the Code of Resistance across Multiple Lines of ALK Inhibitor Therapy in Lung Cancer.
Qiao H, Lovly CM
(2016) Cancer Discov 6: 1084-1086
MeSH Terms: Carcinoma, Non-Small-Cell Lung, Drug Resistance, Neoplasm, Humans, Lung Neoplasms, Protein Kinase Inhibitors, Pyrazoles, Pyridines, Receptor Protein-Tyrosine Kinases
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Diverse, Biologically Relevant, and Targetable Gene Rearrangements in Triple-Negative Breast Cancer and Other Malignancies.
Shaver TM, Lehmann BD, Beeler JS, Li CI, Li Z, Jin H, Stricker TP, Shyr Y, Pietenpol JA
(2016) Cancer Res 76: 4850-60
MeSH Terms: Algorithms, Cell Line, Tumor, Female, Gene Expression Profiling, Gene Rearrangement, Humans, Immunoblotting, Neoplasms, Oncogene Proteins, Fusion, Polymerase Chain Reaction, Proto-Oncogene Mas, Proto-Oncogene Proteins, Receptor Protein-Tyrosine Kinases, Triple Negative Breast Neoplasms, c-Mer Tyrosine Kinase
Added April 9, 2017
1 Communities
1 Members
0 Resources
15 MeSH Terms
Tyrosine Kinase Signaling in Clear Cell and Papillary Renal Cell Carcinoma Revealed by Mass Spectrometry-Based Phosphotyrosine Proteomics.
Haake SM, Li J, Bai Y, Kinose F, Fang B, Welsh EA, Zent R, Dhillon J, Pow-Sang JM, Chen YA, Koomen JM, Rathmell WK, Fishman M, Haura EB
(2016) Clin Cancer Res 22: 5605-5616
MeSH Terms: Carcinoma, Papillary, Carcinoma, Renal Cell, Cell Line, Tumor, Cell Survival, ErbB Receptors, Extracellular Matrix, Humans, Kidney Neoplasms, Mass Spectrometry, Phosphorylation, Phosphotyrosine, Protein Kinase Inhibitors, Protein-Tyrosine Kinases, Proteomics, Receptor Protein-Tyrosine Kinases, Signal Transduction, Tyrosine
Added August 8, 2016
1 Communities
2 Members
0 Resources
17 MeSH Terms
Histology-Specific Uses of Tyrosine Kinase Inhibitors in Non-gastrointestinal Stromal Tumor Sarcomas.
Sethi TK, Keedy VL
(2016) Curr Treat Options Oncol 17: 11
MeSH Terms: Antineoplastic Agents, Bone Neoplasms, Gastrointestinal Stromal Tumors, Humans, Protein Kinase Inhibitors, Protein-Tyrosine Kinases, Receptor Protein-Tyrosine Kinases, Sarcoma, Signal Transduction
Added March 16, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms