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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 5 of 5

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Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth.
Grohar PJ, Segars LE, Yeung C, Pommier Y, D'Incalci M, Mendoza A, Helman LJ
(2014) Clin Cancer Res 20: 1190-203
MeSH Terms: Animals, Antineoplastic Agents, Camptothecin, Cell Line, Tumor, DNA Breaks, Double-Stranded, DNA Damage, Dioxoles, Disease Models, Animal, Doxorubicin, Drug Resistance, Neoplasm, Drug Synergism, Exodeoxyribonucleases, Female, Gene Expression Regulation, Neoplastic, Gene Silencing, Humans, Irinotecan, Mice, Oncogene Proteins, Fusion, Phenotype, Proto-Oncogene Protein c-fli-1, RNA Interference, RNA, Small Interfering, RNA-Binding Protein EWS, RecQ Helicases, Sarcoma, Ewing, Tetrahydroisoquinolines, Trabectedin, Werner Syndrome Helicase, Xenograft Model Antitumor Assays
Added March 5, 2014
0 Communities
1 Members
0 Resources
30 MeSH Terms
Identification and characterization of SMARCAL1 protein complexes.
B├ętous R, Glick GG, Zhao R, Cortez D
(2013) PLoS One 8: e63149
MeSH Terms: Cell Line, Tumor, DNA, DNA Breaks, Double-Stranded, DNA Helicases, DNA Repair, DNA Replication, DNA-Binding Proteins, Endonucleases, Exodeoxyribonucleases, HEK293 Cells, HeLa Cells, Humans, Immunoblotting, Immunoprecipitation, Mass Spectrometry, Nucleic Acid Conformation, Protein Binding, Proteomics, RecQ Helicases, Replication Protein A, S Phase, Werner Syndrome Helicase
Added March 5, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Replication protein A stimulates the Werner syndrome protein branch migration activity.
Sowd G, Wang H, Pretto D, Chazin WJ, Opresko PL
(2009) J Biol Chem 284: 34682-91
MeSH Terms: Animals, DNA Replication, DNA, Single-Stranded, Exodeoxyribonucleases, Humans, Nucleic Acid Conformation, RecQ Helicases, Recombination, Genetic, Replication Protein A, Telomere, Telomere-Binding Proteins, Werner Syndrome, Werner Syndrome Helicase
Added March 12, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Identification of the SSB binding site on E. coli RecQ reveals a conserved surface for binding SSB's C terminus.
Shereda RD, Reiter NJ, Butcher SE, Keck JL
(2009) J Mol Biol 386: 612-25
MeSH Terms: Amino Acid Substitution, Binding Sites, Conserved Sequence, DNA Mutational Analysis, DNA-Binding Proteins, Electrophoretic Mobility Shift Assay, Escherichia coli, Escherichia coli Proteins, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Protein Binding, Protein Interaction Mapping, Protein Structure, Tertiary, RecQ Helicases
Added January 28, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.
Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J
(2000) Genes Dev 14: 927-39
MeSH Terms: Adenosine Triphosphatases, BRCA1 Protein, Cell Cycle, Cell Cycle Proteins, Cell Nucleus, DNA Helicases, DNA Repair, DNA-Binding Proteins, Endodeoxyribonucleases, Exodeoxyribonucleases, Fluorescent Antibody Technique, Fungal Proteins, HeLa Cells, Humans, Mass Spectrometry, Nuclear Proteins, Precipitin Tests, Protein Binding, RecQ Helicases, Replication Protein C, Saccharomyces cerevisiae Proteins, Signal Transduction, Transcription, Genetic
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms