Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 27

Publication Record

Connections

Loss of in Monocyte/Macrophages Suppresses Their Proliferation and Viability Reducing Atherosclerosis in LDLR Null Mice.
Babaev VR, Huang J, Ding L, Zhang Y, May JM, Linton MF
(2018) Front Immunol 9: 215
MeSH Terms: Animals, Aorta, Atherosclerosis, Cell Proliferation, Cell Survival, Diet, Western, Disease Models, Animal, Female, Humans, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Monocytes, Rapamycin-Insensitive Companion of mTOR Protein, Receptors, LDL
Added April 10, 2018
0 Communities
1 Members
0 Resources
17 MeSH Terms
Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.
Werfel TA, Wang S, Jackson MA, Kavanaugh TE, Joly MM, Lee LH, Hicks DJ, Sanchez V, Ericsson PG, Kilchrist KV, Dimobi SC, Sarett SM, Brantley-Sieders DM, Cook RS, Duvall CL
(2018) Cancer Res 78: 1845-1858
MeSH Terms: Animals, Antineoplastic Agents, Cell Proliferation, Cell Survival, Disease Models, Animal, Female, Humans, Lapatinib, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Inbred BALB C, Mice, Nude, Nanoparticles, Protein Kinase Inhibitors, RNA, Small Interfering, Rapamycin-Insensitive Companion of mTOR Protein, Receptor, ErbB-2, Triple Negative Breast Neoplasms, Xenograft Model Antitumor Assays
Added March 14, 2018
0 Communities
2 Members
0 Resources
19 MeSH Terms
Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination.
Grier MD, West KL, Kelm ND, Fu C, Does MD, Parker B, McBrier E, Lagrange AH, Ess KC, Carson RP
(2017) PLoS One 12: e0188417
MeSH Terms: Animals, Cell Differentiation, Cell Proliferation, Central Nervous System, Gene Expression Regulation, Developmental, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Knockout, Myelin Sheath, Oligodendrocyte Precursor Cells, Rapamycin-Insensitive Companion of mTOR Protein, Signal Transduction, White Matter
Added March 14, 2018
0 Communities
2 Members
0 Resources
14 MeSH Terms
Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Morrison Joly M, Williams MM, Hicks DJ, Jones B, Sanchez V, Young CD, Sarbassov DD, Muller WJ, Brantley-Sieders D, Cook RS
(2017) Breast Cancer Res 19: 74
MeSH Terms: Animals, Breast Neoplasms, Cell Line, Tumor, Cell Movement, Disease Models, Animal, Female, Gene Amplification, Heterografts, Humans, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Transgenic, Neoplasm Metastasis, Neoplasm Staging, Prognosis, Proto-Oncogene Proteins c-akt, Rapamycin-Insensitive Companion of mTOR Protein, Receptor, ErbB-2, Signal Transduction, rac1 GTP-Binding Protein, rho Guanine Nucleotide Dissociation Inhibitor beta
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis.
Tassone B, Saoncella S, Neri F, Ala U, Brusa D, Magnuson MA, Provero P, Oliviero S, Riganti C, Calautti E
(2017) Cell Death Differ 24: 731-746
MeSH Terms: Acetylcysteine, Animals, Apoptosis, Cell Proliferation, Cells, Cultured, Cellular Senescence, Epirubicin, Glutamic Acid, Hyperplasia, Keratin-14, Keratinocytes, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria, Radiation Tolerance, Rapamycin-Insensitive Companion of mTOR Protein, Reactive Oxygen Species, Skin, Tetradecanoylphorbol Acetate, Transcriptome, X-Rays
Added March 7, 2017
2 Communities
1 Members
0 Resources
22 MeSH Terms
Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers.
Morrison Joly M, Hicks DJ, Jones B, Sanchez V, Estrada MV, Young C, Williams M, Rexer BN, Sarbassov dos D, Muller WJ, Brantley-Sieders D, Cook RS
(2016) Cancer Res 76: 4752-64
MeSH Terms: Animals, Blotting, Western, Breast Neoplasms, Carrier Proteins, Disease Progression, Drug Resistance, Neoplasm, Female, Heterografts, Humans, Kaplan-Meier Estimate, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Inbred BALB C, Mice, Nude, Multiprotein Complexes, Rapamycin-Insensitive Companion of mTOR Protein, Receptor, ErbB-2, Signal Transduction, TOR Serine-Threonine Kinases, Tissue Array Analysis
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Evaluation of diffusion kurtosis imaging in ex vivo hypomyelinated mouse brains.
Kelm ND, West KL, Carson RP, Gochberg DF, Ess KC, Does MD
(2016) Neuroimage 124: 612-626
MeSH Terms: Animals, Axons, Brain, Carrier Proteins, Diffusion, Diffusion Tensor Imaging, Disease Models, Animal, Magnetic Resonance Imaging, Mice, Mice, Knockout, Myelin Sheath, Rapamycin-Insensitive Companion of mTOR Protein, Tuberous Sclerosis, Tuberous Sclerosis Complex 2 Protein, Tumor Suppressor Proteins, White Matter
Added February 16, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.
Morrison MM, Young CD, Wang S, Sobolik T, Sanchez VM, Hicks DJ, Cook RS, Brantley-Sieders DM
(2015) PLoS Genet 11: e1005291
MeSH Terms: Animals, Carrier Proteins, Cell Line, Cell Movement, Cell Survival, Female, Mammary Glands, Animal, Mammary Neoplasms, Animal, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Inbred C57BL, Mice, Transgenic, Morphogenesis, Multiprotein Complexes, Neoplasm Invasiveness, Neuropeptides, Organ Culture Techniques, Phosphorylation, Protein Kinase C-alpha, Proto-Oncogene Proteins c-akt, Rapamycin-Insensitive Companion of mTOR Protein, TOR Serine-Threonine Kinases, rac1 GTP-Binding Protein
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
mTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission.
Dadalko OI, Siuta M, Poe A, Erreger K, Matthies HJ, Niswender K, Galli A
(2015) J Neurosci 35: 8843-54
MeSH Terms: Amphetamine, Animals, Carrier Proteins, Dopamine, Dopamine Agents, Dopamine Plasma Membrane Transport Proteins, Dose-Response Relationship, Drug, Gene Expression Regulation, Haloperidol, In Vitro Techniques, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Motor Activity, Nestin, Oncogene Protein v-akt, Rapamycin-Insensitive Companion of mTOR Protein, Serine, Signal Transduction, Synaptic Transmission, Tyrosine 3-Monooxygenase
Added February 15, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
mTORC2 regulates cardiac response to stress by inhibiting MST1.
Sciarretta S, Zhai P, Maejima Y, Del Re DP, Nagarajan N, Yee D, Liu T, Magnuson MA, Volpe M, Frati G, Li H, Sadoshima J
(2015) Cell Rep 11: 125-36
MeSH Terms: Animals, Carrier Proteins, Cell Proliferation, Cell Survival, Heart, Hepatocyte Growth Factor, Humans, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Knockout, Multiprotein Complexes, Myocardium, Protein Multimerization, Proto-Oncogene Proteins, Rapamycin-Insensitive Companion of mTOR Protein, Signal Transduction, Stress, Mechanical, TOR Serine-Threonine Kinases
Added April 7, 2015
2 Communities
1 Members
0 Resources
18 MeSH Terms