Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 12

Publication Record

Connections

Use of deep whole-genome sequencing data to identify structure risk variants in breast cancer susceptibility genes.
Guo X, Shi J, Cai Q, Shu XO, He J, Wen W, Allen J, Pharoah P, Dunning A, Hunter DJ, Kraft P, Easton DF, Zheng W, Long J
(2018) Hum Mol Genet 27: 853-859
MeSH Terms: BRCA1 Protein, Breast Neoplasms, Fanconi Anemia Complementation Group N Protein, Female, Genetic Predisposition to Disease, Genome, Human, High-Throughput Nucleotide Sequencing, Humans, Membrane Proteins, PTEN Phosphohydrolase, Rad51 Recombinase, Sequence Deletion, Tumor Suppressor Protein p53
Added April 3, 2018
0 Communities
3 Members
0 Resources
13 MeSH Terms
RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.
Dungrawala H, Bhat KP, Le Meur R, Chazin WJ, Ding X, Sharan SK, Wessel SR, Sathe AA, Zhao R, Cortez D
(2017) Mol Cell 67: 374-386.e5
MeSH Terms: A549 Cells, Animals, BRCA2 Protein, CRISPR-Cas Systems, DNA Breaks, Double-Stranded, DNA Repair, DNA, Neoplasm, Dose-Response Relationship, Drug, Drug Resistance, Neoplasm, Gene Expression Regulation, Neoplastic, Genomic Instability, HEK293 Cells, Humans, Mice, Models, Molecular, Mutation, Neoplasms, Poly(ADP-ribose) Polymerase Inhibitors, Protein Binding, RNA Interference, Rad51 Recombinase, Replication Origin, Transfection
Added March 24, 2018
0 Communities
1 Members
0 Resources
23 MeSH Terms
EGFR Fusions as Novel Therapeutic Targets in Lung Cancer.
Konduri K, Gallant JN, Chae YK, Giles FJ, Gitlitz BJ, Gowen K, Ichihara E, Owonikoko TK, Peddareddigari V, Ramalingam SS, Reddy SK, Eaby-Sandy B, Vavalà T, Whiteley A, Chen H, Yan Y, Sheehan JH, Meiler J, Morosini D, Ross JS, Stephens PJ, Miller VA, Ali SM, Lovly CM
(2016) Cancer Discov 6: 601-11
MeSH Terms: Adult, Antineoplastic Agents, Biomarkers, Cell Line, Tumor, Combined Modality Therapy, ErbB Receptors, Exons, Female, Genetic Loci, High-Throughput Nucleotide Sequencing, Humans, Introns, Lung Neoplasms, Magnetic Resonance Imaging, Male, Middle Aged, Models, Molecular, Molecular Targeted Therapy, Neoplasm Metastasis, Oncogene Proteins, Fusion, Protein Conformation, Protein Kinase Inhibitors, Rad51 Recombinase, Young Adult
Added April 8, 2017
1 Communities
3 Members
0 Resources
24 MeSH Terms
Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.
Zhao W, Vaithiyalingam S, San Filippo J, Maranon DG, Jimenez-Sainz J, Fontenay GV, Kwon Y, Leung SG, Lu L, Jensen RB, Chazin WJ, Wiese C, Sung P
(2015) Mol Cell 59: 176-87
MeSH Terms: Amino Acid Substitution, BRCA2 Protein, Breast Neoplasms, Cell Line, Female, HeLa Cells, Homologous Recombination, Humans, Models, Biological, Molecular Mimicry, Mutagenesis, Site-Directed, Nuclear Magnetic Resonance, Biomolecular, Proteasome Endopeptidase Complex, Protein Subunits, Rad51 Recombinase, Recombinant Proteins, Replication Protein A
Added February 5, 2016
1 Communities
2 Members
0 Resources
17 MeSH Terms
Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization.
Sekhar KR, Benamar M, Venkateswaran A, Sasi S, Penthala NR, Crooks PA, Hann SR, Geng L, Balusu R, Abbas T, Freeman ML
(2014) Int J Radiat Oncol Biol Phys 89: 1106-1114
MeSH Terms: Animals, Barbiturates, Carcinoma, Non-Small-Cell Lung, DNA Breaks, Double-Stranded, DNA Repair, Fibroblasts, Histones, Humans, Indoles, Lung Neoplasms, Mice, Mice, Inbred C57BL, Mice, Nude, Molecular Targeted Therapy, Neoplasm Proteins, Nuclear Proteins, Rad51 Recombinase, Radiation Tolerance, Radiation-Sensitizing Agents, Tissue Array Analysis, Tumor Cells, Cultured
Added January 20, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
RAD51 as a potential biomarker and therapeutic target for pancreatic cancer.
Nagathihalli NS, Nagaraju G
(2011) Biochim Biophys Acta 1816: 209-18
MeSH Terms: Animals, Biomarkers, Tumor, Disease Progression, Drug Resistance, Neoplasm, Epithelial-Mesenchymal Transition, Humans, MicroRNAs, Neoplastic Stem Cells, Pancreatic Neoplasms, Rad51 Recombinase
Added June 14, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers.
Vilar E, Bartnik CM, Stenzel SL, Raskin L, Ahn J, Moreno V, Mukherjee B, Iniesta MD, Morgan MA, Rennert G, Gruber SB
(2011) Cancer Res 71: 2632-42
MeSH Terms: Acid Anhydride Hydrolases, Benzimidazoles, Cell Line, Tumor, Colorectal Neoplasms, DNA Damage, DNA Repair Enzymes, DNA-Binding Proteins, Enzyme Inhibitors, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Gene Knockdown Techniques, Humans, MRE11 Homologue Protein, Microsatellite Instability, Mutation, Poly (ADP-Ribose) Polymerase-1, Poly(ADP-ribose) Polymerase Inhibitors, Poly(ADP-ribose) Polymerases, Rad51 Recombinase, Recombination, Genetic
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair.
Wiltshire TD, Lovejoy CA, Wang T, Xia F, O'Connor MJ, Cortez D
(2010) J Biol Chem 285: 14565-71
MeSH Terms: Blotting, Western, Bone Neoplasms, Cell Survival, DNA Breaks, Double-Stranded, DNA Repair, Fluorescent Antibody Technique, Humans, Intracellular Signaling Peptides and Proteins, Osteosarcoma, Phthalazines, Piperazines, Poly(ADP-ribose) Polymerase Inhibitors, Poly(ADP-ribose) Polymerases, RNA, Messenger, RNA, Small Interfering, Rad51 Recombinase, Radiation, Ionizing, Recombination, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Thiolester Hydrolases, Tumor Cells, Cultured, Tumor Stem Cell Assay, Tumor Suppressor p53-Binding Protein 1
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.
Antoniou AC, Sinilnikova OM, Simard J, Léoné M, Dumont M, Neuhausen SL, Struewing JP, Stoppa-Lyonnet D, Barjhoux L, Hughes DJ, Coupier I, Belotti M, Lasset C, Bonadona V, Bignon YJ, Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers Study (GEMO), Rebbeck TR, Wagner T, Lynch HT, Domchek SM, Nathanson KL, Garber JE, Weitzel J, Narod SA, Tomlinson G, Olopade OI, Godwin A, Isaacs C, Jakubowska A, Lubinski J, Gronwald J, Górski B, Byrski T, Huzarski T, Peock S, Cook M, Baynes C, Murray A, Rogers M, Daly PA, Dorkins H, Epidemiological Study of BRCA1 and BRCA2 Mutation Carriers (EMBRACE), Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Niederacher D, Deissler H, German Consortium for Hereditary Breast and Ovarian Cancer (GCHBOC), Spurdle AB, Chen X, Waddell N, Cloonan N, Kathleen Cuningham Consortium for Research into Familial Breast Cancer (kConFab), Kirchhoff T, Offit K, Friedman E, Kaufmann B, Laitman Y, Galore G, Rennert G, Lejbkowicz F, Raskin L, Andrulis IL, Ilyushik E, Ozcelik H, Devilee P, Vreeswijk MP, Greene MH, Prindiville SA, Osorio A, Benitez J, Zikan M, Szabo CI, Kilpivaara O, Nevanlinna H, Hamann U, Durocher F, Arason A, Couch FJ, Easton DF, Chenevix-Trench G, Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)
(2007) Am J Hum Genet 81: 1186-200
MeSH Terms: Adolescent, Adult, Alternative Splicing, BRCA1 Protein, BRCA2 Protein, Breast Neoplasms, DNA Primers, DNA Repair, Family, Female, Genetic Variation, Heterozygote, Homozygote, Humans, Middle Aged, Mutation, Polymorphism, Single Nucleotide, Rad51 Recombinase, Reverse Transcriptase Polymerase Chain Reaction
Added March 10, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Swi1 and Swi3 are components of a replication fork protection complex in fission yeast.
Noguchi E, Noguchi C, McDonald WH, Yates JR, Russell P
(2004) Mol Cell Biol 24: 8342-55
MeSH Terms: Amino Acid Sequence, Cell Cycle Proteins, Chromatin, DNA Helicases, DNA-Binding Proteins, DNA-Directed DNA Polymerase, Endonucleases, Molecular Sequence Data, Nuclear Proteins, Rad51 Recombinase, S Phase, Saccharomyces cerevisiae Proteins, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Trans-Activators, Transcription Factors, Transcription, Genetic
Added March 20, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms