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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 28

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Genetic Variants Associated with Circulating Fibroblast Growth Factor 23.
Robinson-Cohen C, Bartz TM, Lai D, Ikizler TA, Peacock M, Imel EA, Michos ED, Foroud TM, Akesson K, Taylor KD, Malmgren L, Matsushita K, Nethander M, Eriksson J, Ohlsson C, Mellström D, Wolf M, Ljunggren O, McGuigan F, Rotter JI, Karlsson M, Econs MJ, Ix JH, Lutsey PL, Psaty BM, de Boer IH, Kestenbaum BR
(2018) J Am Soc Nephrol 29: 2583-2592
MeSH Terms: Blacks, Cohort Studies, Female, Fibroblast Growth Factor-23, Fibroblast Growth Factors, Genome-Wide Association Study, Humans, Kidney, Male, Phosphates, Polymorphism, Single Nucleotide, RGS Proteins, Sodium-Phosphate Cotransporter Proteins, Type IIa, Vitamin D, Vitamin D3 24-Hydroxylase, Whites
Added January 3, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia.
Shen W, Plotkin JL, Francardo V, Ko WK, Xie Z, Li Q, Fieblinger T, Wess J, Neubig RR, Lindsley CW, Conn PJ, Greengard P, Bezard E, Cenci MA, Surmeier DJ
(2015) Neuron 88: 762-73
MeSH Terms: Allosteric Regulation, Animals, Cerebral Cortex, Disease Models, Animal, Dopamine Agents, Dyskinesia, Drug-Induced, Glutamic Acid, Levodopa, Long-Term Potentiation, Long-Term Synaptic Depression, Macaca mulatta, Mice, Mice, Transgenic, Neostriatum, Neuronal Plasticity, Neurons, Parkinsonian Disorders, RGS Proteins, Receptor, Muscarinic M4, Signal Transduction
Added February 18, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells.
Altman MK, Alshamrani AA, Jia W, Nguyen HT, Fambrough JM, Tran SK, Patel MB, Hoseinzadeh P, Beedle AM, Murph MM
(2015) Cancer Lett 369: 175-83
MeSH Terms: Cell Line, Tumor, Cell Survival, Female, Humans, Monomeric GTP-Binding Proteins, Neuropeptides, Ovarian Neoplasms, Phosphorylation, Protein Processing, Post-Translational, RGS Proteins, Ras Homolog Enriched in Brain Protein, Signal Transduction, TOR Serine-Threonine Kinases
Added September 20, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms
GRK3 suppresses L-DOPA-induced dyskinesia in the rat model of Parkinson's disease via its RGS homology domain.
Ahmed MR, Bychkov E, Li L, Gurevich VV, Gurevich EV
(2015) Sci Rep 5: 10920
MeSH Terms: Animals, Behavior, Animal, Corpus Striatum, Disease Models, Animal, Dyskinesias, G-Protein-Coupled Receptor Kinase 3, Gene Expression, Gene Knockdown Techniques, Levodopa, Parkinson Disease, Protein Interaction Domains and Motifs, RGS Proteins, RNA Interference, RNA, Small Interfering, Rats, Signal Transduction
Added February 15, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis.
Stewart A, Maity B, Wunsch AM, Meng F, Wu Q, Wemmie JA, Fisher RA
(2014) FASEB J 28: 1735-44
MeSH Terms: 8-Hydroxy-2-(di-n-propylamino)tetralin, Adenylyl Cyclases, Animals, Animals, Newborn, Anxiety, Cells, Cultured, Cerebral Cortex, Depression, Female, Fluvoxamine, Hippocampus, Immunoblotting, Immunohistochemistry, Male, Mice, Phosphorylation, Piperazines, Proto-Oncogene Proteins c-akt, Pyridines, RGS Proteins, Receptor, Serotonin, 5-HT1A, Serotonin, Serotonin Antagonists, Serotonin Receptor Agonists, Serotonin Uptake Inhibitors, Signal Transduction
Added August 7, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms
Regulator of G protein signaling 6 is a novel suppressor of breast tumor initiation and progression.
Maity B, Stewart A, O'Malley Y, Askeland RW, Sugg SL, Fisher RA
(2013) Carcinogenesis 34: 1747-55
MeSH Terms: 9,10-Dimethyl-1,2-benzanthracene, Animals, Apoptosis, Ataxia Telangiectasia Mutated Proteins, Breast Neoplasms, Carcinogenesis, Cell Line, Tumor, DNA Damage, Disease Progression, Epithelial Cells, ErbB Receptors, Female, Humans, MCF-7 Cells, Mammary Neoplasms, Experimental, Mice, Mice, Inbred C57BL, RGS Proteins, Reactive Oxygen Species, Receptors, Estrogen, Signal Transduction, Tumor Suppressor Protein p53
Added August 7, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
G-protein inactivator RGS6 mediates myocardial cell apoptosis and cardiomyopathy caused by doxorubicin.
Yang J, Maity B, Huang J, Gao Z, Stewart A, Weiss RM, Anderson ME, Fisher RA
(2013) Cancer Res 73: 1662-7
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Cardiomyopathies, Doxorubicin, GTP-Binding Proteins, Humans, Mice, Mice, Inbred C57BL, Mice, Knockout, Myocardium, RGS Proteins, Reactive Oxygen Species
Added August 7, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Regulator of G protein signaling 6 (RGS6) protein ensures coordination of motor movement by modulating GABAB receptor signaling.
Maity B, Stewart A, Yang J, Loo L, Sheff D, Shepherd AJ, Mohapatra DP, Fisher RA
(2012) J Biol Chem 287: 4972-81
MeSH Terms: Animals, Baclofen, Cerebellar Ataxia, Cerebellum, G Protein-Coupled Inwardly-Rectifying Potassium Channels, GABA-B Receptor Agonists, GABAergic Neurons, GTP-Binding Protein beta Subunits, Humans, Locomotion, Mice, Mice, Knockout, Motor Activity, Multiprotein Complexes, Nerve Tissue Proteins, RGS Proteins, Receptors, GABA-B, Signal Transduction
Added August 7, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of MCP-1.
Boelte KC, Gordy LE, Joyce S, Thompson MA, Yang L, Lin PC
(2011) PLoS One 6: e18534
MeSH Terms: Animals, Cell Death, Cell Differentiation, Cell Movement, Cell Proliferation, Chemokine CCL2, Endothelial Cells, Gene Deletion, Gene Expression Regulation, Neoplastic, Humans, Mice, Mice, Inbred C57BL, Myeloid Cells, Neoplasms, Neovascularization, Pathologic, RGS Proteins, Signal Transduction, Tumor Microenvironment, Up-Regulation
Added May 19, 2014
0 Communities
2 Members
0 Resources
19 MeSH Terms
Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells.
Hooks SB, Callihan P, Altman MK, Hurst JH, Ali MW, Murph MM
(2010) Mol Cancer 9: 289
MeSH Terms: Antineoplastic Agents, Cell Line, Tumor, Cell Survival, Cisplatin, Computational Biology, Docetaxel, Drug Resistance, Neoplasm, Female, Humans, Lysophospholipids, Ovarian Neoplasms, Polymerase Chain Reaction, RGS Proteins, Signal Transduction, Taxoids, Vincristine
Added September 20, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms