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Results: 1 to 4 of 4

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Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α.
Jiang JY, Nagaraju M, Meyer RC, Zhang L, Hamelberg D, Hall RA, Brown EM, Conn PJ, Yang JJ
(2014) J Biol Chem 289: 1649-61
MeSH Terms: Allosteric Regulation, Amino Acid Substitution, Benzoates, Binding Sites, Calcium, Calcium Signaling, Carbamates, Excitatory Amino Acid Agonists, Glycine, HEK293 Cells, Humans, Mutation, Missense, Protein Structure, Tertiary, Quisqualic Acid, Receptors, Metabotropic Glutamate, Xanthenes
Added February 19, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Quisqualate selectively inhibits a brain peptidase which cleaves N-acetyl-L-aspartyl-L-glutamate in vitro.
Robinson MB, Blakely RD, Coyle JT
(1986) Eur J Pharmacol 130: 345-7
MeSH Terms: Animals, Brain, Dipeptides, In Vitro Techniques, Kinetics, Oxadiazoles, Protease Inhibitors, Quisqualic Acid, Rats, Synaptic Membranes
Added July 10, 2013
1 Communities
1 Members
0 Resources
10 MeSH Terms
Synaptosomal transport of radiolabel from N-acetyl-aspartyl-[3H]glutamate suggests a mechanism of inactivation of an excitatory neuropeptide.
Blakely RD, Ory-Lavollée L, Thompson RC, Coyle JT
(1986) J Neurochem 47: 1013-9
MeSH Terms: Amino Acids, Animals, Biological Transport, Brain, Dipeptides, Glutamates, Glutamic Acid, Kinetics, Male, Oxadiazoles, Quisqualic Acid, Rats, Rats, Inbred Strains, Sodium, Synaptosomes, Tritium
Added July 10, 2013
1 Communities
1 Members
0 Resources
16 MeSH Terms
Metabotropic excitatory amino acid receptor activation stimulates phospholipase D in hippocampal slices.
Boss V, Conn PJ
(1992) J Neurochem 59: 2340-3
MeSH Terms: Animals, Autoradiography, Cycloleucine, Diglycerides, Dose-Response Relationship, Drug, Enzyme Activation, Hippocampus, Ibotenic Acid, Organ Culture Techniques, Phospholipase D, Quisqualic Acid, Receptors, Amino Acid
Added February 19, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms