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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 8 of 8

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Comparative Proteome Profiling during Cardiac Hypertrophy and Myocardial Infarction Reveals Altered Glucose Oxidation by Differential Activation of Pyruvate Dehydrogenase E1 Component Subunit β.
Mitra A, Basak T, Ahmad S, Datta K, Datta R, Sengupta S, Sarkar S
(2015) J Mol Biol 427: 2104-20
MeSH Terms: Adenosine Triphosphate, Animals, Cardiomegaly, Case-Control Studies, Disease Models, Animal, Electrophoresis, Gel, Two-Dimensional, Energy Metabolism, Enzyme Activation, Glucose, Male, Myocardial Infarction, Oxidation-Reduction, Phosphorylation, Protein-Serine-Threonine Kinases, Proteomics, Pyruvate Dehydrogenase (Lipoamide), Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Rats, Wistar, Reproducibility of Results, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Added November 3, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms
Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians.
Hwang JY, Sim X, Wu Y, Liang J, Tabara Y, Hu C, Hara K, Tam CH, Cai Q, Zhao Q, Jee S, Takeuchi F, Go MJ, Ong RT, Ohkubo T, Kim YJ, Zhang R, Yamauchi T, So WY, Long J, Gu D, Lee NR, Kim S, Katsuya T, Oh JH, Liu J, Umemura S, Kim YJ, Jiang F, Maeda S, Chan JC, Lu W, Hixson JE, Adair LS, Jung KJ, Nabika T, Bae JB, Lee MH, Seielstad M, Young TL, Teo YY, Kita Y, Takashima N, Osawa H, Lee SH, Shin MH, Shin DH, Choi BY, Shi J, Gao YT, Xiang YB, Zheng W, Kato N, Yoon M, He J, Shu XO, Ma RC, Kadowaki T, Jia W, Miki T, Qi L, Tai ES, Mohlke KL, Han BG, Cho YS, Kim BJ
(2015) Diabetes 64: 291-8
MeSH Terms: Adaptor Proteins, Signal Transducing, Adult, Aged, Asian Continental Ancestry Group, Blood Glucose, Cytoskeletal Proteins, Far East, Fasting, Female, Genetic Variation, Genome-Wide Association Study, Genotype, Guanine Nucleotide Exchange Factors, Humans, Male, Middle Aged, Phenotype, Protein-Serine-Threonine Kinases, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Receptor, IGF Type 1, Tumor Suppressor Proteins
Added February 22, 2016
0 Communities
2 Members
0 Resources
21 MeSH Terms
Liver, but not muscle, has an entrainable metabolic memory.
Chen SS, Otero YF, Mulligan KX, Lundblad TM, Williams PE, McGuinness OP
(2014) PLoS One 9: e86164
MeSH Terms: AMP-Activated Protein Kinases, Animals, Blood Glucose, Dogs, Energy Metabolism, Female, Glucagon, Glycogen, Glycogen Synthase, Insulin, Lactic Acid, Lipid Metabolism, Liver, Male, Muscle, Skeletal, Oxidation-Reduction, Protein-Serine-Threonine Kinases, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Pyruvic Acid
Added July 21, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia.
Lee K, Nam KT, Cho SH, Gudapati P, Hwang Y, Park DS, Potter R, Chen J, Volanakis E, Boothby M
(2012) J Exp Med 209: 713-28
MeSH Terms: Active Transport, Cell Nucleus, Animals, Carrier Proteins, Cell Differentiation, Cell Lineage, Forkhead Box Protein O1, Forkhead Transcription Factors, Mice, Mice, Inbred C57BL, NF-kappa B, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-akt, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Rapamycin-Insensitive Companion of mTOR Protein, Receptors, Notch, TOR Serine-Threonine Kinases, Thymocytes
Added December 10, 2013
2 Communities
3 Members
0 Resources
18 MeSH Terms
Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin II-induced, PKC-alpha-dependent Akt activation in endosomes.
Nazarewicz RR, Salazar G, Patrushev N, San Martin A, Hilenski L, Xiong S, Alexander RW
(2011) J Biol Chem 286: 2886-95
MeSH Terms: Angiotensin II, Animals, Cells, Cultured, Endosomes, Enzyme Induction, Mitogen-Activated Protein Kinase 3, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, Phosphorylation, Protein Kinase C-alpha, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-akt, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Rats, Rats, Sprague-Dawley, TOR Serine-Threonine Kinases, Vasoconstrictor Agents, Vesicular Transport Proteins, p38 Mitogen-Activated Protein Kinases
Added June 9, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.
Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA
(2009) Cancer Cell 16: 21-32
MeSH Terms: Breast Neoplasms, Cell Line, Tumor, Cell Survival, Class I Phosphatidylinositol 3-Kinases, Enzyme Activation, Female, Gene Expression Profiling, Humans, Mutation, Neoplasms, PTEN Phosphohydrolase, Phosphatidylinositol 3-Kinases, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-akt, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Signal Transduction
Added November 26, 2018
0 Communities
1 Members
0 Resources
16 MeSH Terms
mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Guertin DA, Stevens DM, Saitoh M, Kinkel S, Crosby K, Sheen JH, Mullholland DJ, Magnuson MA, Wu H, Sabatini DM
(2009) Cancer Cell 15: 148-59
MeSH Terms: Animals, Carrier Proteins, Cell Transformation, Neoplastic, Cells, Cultured, Epithelial Cells, Fibroblasts, Humans, Male, Mice, Mice, Inbred BALB C, Mice, Nude, Neoplasm Transplantation, PTEN Phosphohydrolase, Phenotype, Phosphotransferases (Alcohol Group Acceptor), Prostate, Prostatic Neoplasms, Protein Kinases, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-akt, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, RNA Interference, Rapamycin-Insensitive Companion of mTOR Protein, Signal Transduction, TOR Serine-Threonine Kinases, Transcription Factors, Transplantation, Heterologous
Added August 22, 2011
3 Communities
1 Members
0 Resources
27 MeSH Terms
Abnormal energy regulation in early life: childhood gene expression may predict subsequent chronic mountain sickness.
Huicho L, Xing G, Qualls C, Rivera-Ch M, Gamboa JL, Verma A, Appenzeller O
(2008) BMC Pediatr 8: 47
MeSH Terms: Adaptation, Physiological, Adolescent, Adult, Altitude, Altitude Sickness, Child, Child, Preschool, Chronic Disease, Citric Acid Cycle, Cross-Sectional Studies, Dioxygenases, Energy Metabolism, Gene Expression, Glycolysis, Hematocrit, Hemoglobin A, Humans, Hypoxia, Hypoxia-Inducible Factor-Proline Dioxygenases, Male, Predictive Value of Tests, Protein-Serine-Threonine Kinases, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, RNA, Messenger, Reverse Transcriptase Polymerase Chain Reaction
Added April 25, 2016
0 Communities
1 Members
0 Resources
25 MeSH Terms