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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 12

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Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA.
Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ
(2018) Nucleic Acids Res 46: 3458-3467
MeSH Terms: Animals, Bone Morphogenetic Protein Receptors, Type II, DNA Adducts, DNA, Mitochondrial, Electron Transport, Endothelial Cells, Gene Expression Regulation, Humans, Hypertension, Pulmonary, Lipid Peroxidation, Mice, Mice, Transgenic, Mitochondria, Mutagenesis, Oxidants, Oxidative Stress, Purine Nucleosides, Reactive Oxygen Species, Superoxides
Added March 14, 2018
0 Communities
3 Members
0 Resources
19 MeSH Terms
Nuclear Oxidation of a Major Peroxidation DNA Adduct, M1dG, in the Genome.
Wauchope OR, Beavers WN, Galligan JJ, Mitchener MM, Kingsley PJ, Marnett LJ
(2015) Chem Res Toxicol 28: 2334-42
MeSH Terms: Adenine, Animals, Cell Nucleus, Cells, Cultured, Chromatography, Liquid, DNA Adducts, HEK293 Cells, Humans, Lipid Peroxidation, Macrophages, Mass Spectrometry, Oxidation-Reduction, Purine Nucleosides
Added February 22, 2016
0 Communities
2 Members
0 Resources
13 MeSH Terms
Semisynthesis of 6-chloropurine-2'-deoxyriboside 5'-dimethoxytrityl 3'-(2-cyanoethyl-N,N-diisopropylamino)phosphoramidite and its use in the synthesis of fluorescently labeled oligonucleotides.
Uddin MJ, Schulte MI, Maddukuri L, Harp J, Marnett LJ
(2010) Nucleosides Nucleotides Nucleic Acids 29: 831-40
MeSH Terms: Cadaverine, Chromatography, Gel, Chromatography, High Pressure Liquid, Crystallography, Fluorescent Dyes, Magnetic Resonance Spectroscopy, Mass Spectrometry, Molecular Structure, Nucleic Acid Conformation, Oligonucleotides, Organophosphorus Compounds, Pentosyltransferases, Purine Nucleosides, Purines, Rhodamines, Spectrometry, Fluorescence
Added March 7, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M1dG.
Cline SD, Lodeiro MF, Marnett LJ, Cameron CE, Arnold JJ
(2010) Nucleic Acids Res 38: 7546-57
MeSH Terms: DNA Adducts, DNA-Directed RNA Polymerases, Deoxyguanosine, Humans, Mitochondria, Promoter Regions, Genetic, Purine Nucleosides, Transcription, Genetic
Added June 1, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Oxidation and glycolytic cleavage of etheno and propano DNA base adducts.
Knutson CG, Rubinson EH, Akingbade D, Anderson CS, Stec DF, Petrova KV, Kozekov ID, Guengerich FP, Rizzo CJ, Marnett LJ
(2009) Biochemistry 48: 800-9
MeSH Terms: Animals, Cattle, DNA Adducts, DNA Repair, Glycolysis, Guanine, Humans, Lipid Peroxidation, Oxidative Stress, Purine Nucleosides, Pyrimidine Nucleosides, Rats
Added March 7, 2014
0 Communities
3 Members
0 Resources
12 MeSH Terms
Translesion DNA synthesis by human DNA polymerase eta on templates containing a pyrimidopurinone deoxyguanosine adduct, 3-(2'-deoxy-beta-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one.
Stafford JB, Eoff RL, Kozekova A, Rizzo CJ, Guengerich FP, Marnett LJ
(2009) Biochemistry 48: 471-80
MeSH Terms: Bacteriophage T4, Base Pair Mismatch, Base Sequence, DNA Adducts, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Escherichia coli, Humans, Kinetics, Mutagenesis, Site-Directed, Phosphorylation, Polynucleotide 5'-Hydroxyl-Kinase, Purine Nucleosides, Recombinant Proteins, Templates, Genetic, Uracil-DNA Glycosidase
Added March 7, 2014
0 Communities
3 Members
0 Resources
17 MeSH Terms
Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin-10(3H)-one}, by accelerator mass spectrometry.
Knutson CG, Skipper PL, Liberman RG, Tannenbaum SR, Marnett LJ
(2008) Chem Res Toxicol 21: 1290-4
MeSH Terms: Animals, DNA Adducts, Feces, Male, Mass Spectrometry, Purine Nucleosides, Rats, Rats, Sprague-Dawley, Urine
Added March 5, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Chemical properties of oxopropenyl adducts of purine and pyrimidine nucleosides and their reactivity toward amino acid cross-link formation.
Szekely J, Rizzo CJ, Marnett LJ
(2008) J Am Chem Soc 130: 2195-201
MeSH Terms: Amino Acids, Cross-Linking Reagents, DNA Adducts, Deoxyguanosine, Kinetics, Lysine, Malondialdehyde, Purine Nucleosides, Pyrimidine Nucleosides
Added March 5, 2014
0 Communities
2 Members
0 Resources
9 MeSH Terms
Metabolism and elimination of the endogenous DNA adduct, 3-(2-deoxy-beta-D-erythropentofuranosyl)-pyrimido[1,2-alpha]purine-10(3H)-one, in the rat.
Knutson CG, Wang H, Rizzo CJ, Marnett LJ
(2007) J Biol Chem 282: 36257-64
MeSH Terms: Animals, Bile, Bile Canaliculi, DNA Adducts, DNA Damage, Genome, Male, Oxidation-Reduction, Purine Nucleosides, Rats, Rats, Sprague-Dawley
Added March 5, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Synthesis of nucleotide analogues by a promiscuous phosphoribosyltransferase.
Scism RA, Stec DF, Bachmann BO
(2007) Org Lett 9: 4179-82
MeSH Terms: Escherichia coli, Hypoxanthine Phosphoribosyltransferase, Mutation, Nuclear Magnetic Resonance, Biomolecular, Purine Nucleosides
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms