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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization.
Plosa EJ, Young LR, Gulleman PM, Polosukhin VV, Zaynagetdinov R, Benjamin JT, Im AM, van der Meer R, Gleaves LA, Bulus N, Han W, Prince LS, Blackwell TS, Zent R
(2014) Development 141: 4751-62
MeSH Terms: Animals, Bronchoalveolar Lavage, Cell Adhesion, Cell Movement, Chemokine CCL2, Enzyme-Linked Immunosorbent Assay, Epithelial Cells, Extracellular Matrix, Integrases, Integrin beta1, Lung, Mice, Microscopy, Confocal, Organogenesis, Pulmonary Alveoli, Pulmonary Surfactant-Associated Protein C, Reactive Oxygen Species, Thiobarbituric Acid Reactive Substances
Added January 20, 2015
1 Communities
4 Members
0 Resources
18 MeSH Terms
Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis.
Kropski JA, Lawson WE, Young LR, Blackwell TS
(2013) Dis Model Mech 6: 9-17
MeSH Terms: Cellular Senescence, DNA Damage, DNA Repair, Endoplasmic Reticulum Stress, Genetic Variation, Hermanski-Pudlak Syndrome, Humans, Idiopathic Pulmonary Fibrosis, Male, Middle Aged, Models, Genetic, Mucin-5B, Mutation, Pulmonary Surfactant-Associated Protein A, Pulmonary Surfactant-Associated Protein C, RNA, Telomerase, Telomere Shortening, Unfolded Protein Response
Added March 5, 2014
1 Communities
2 Members
0 Resources
19 MeSH Terms
Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis.
Tanjore H, Blackwell TS, Lawson WE
(2012) Am J Physiol Lung Cell Mol Physiol 302: L721-9
MeSH Terms: Aging, Animals, Apoptosis, Bleomycin, Endoplasmic Reticulum Stress, Epithelial-Mesenchymal Transition, Humans, Idiopathic Pulmonary Fibrosis, Inflammation, Mice, Pulmonary Alveoli, Pulmonary Surfactant-Associated Protein C, Smoking, Unfolded Protein Response
Added March 5, 2014
1 Communities
2 Members
0 Resources
14 MeSH Terms
Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress.
Tanjore H, Cheng DS, Degryse AL, Zoz DF, Abdolrasulnia R, Lawson WE, Blackwell TS
(2011) J Biol Chem 286: 30972-30980
MeSH Terms: Acetylcysteine, Animals, Cadherins, Endoplasmic Reticulum, Epithelium, Fibrosis, Humans, Membrane Proteins, Mesoderm, Mice, Microscopy, Phase-Contrast, Models, Biological, Mutation, Phosphoproteins, Pulmonary Alveoli, Pulmonary Surfactant-Associated Protein C, Rats, Tunicamycin, Zonula Occludens-1 Protein
Added March 5, 2014
1 Communities
2 Members
0 Resources
19 MeSH Terms
A nonaggregating surfactant protein C mutant is misdirected to early endosomes and disrupts phospholipid recycling.
Beers MF, Hawkins A, Maguire JA, Kotorashvili A, Zhao M, Newitt JL, Ding W, Russo S, Guttentag S, Gonzales L, Mulugeta S
(2011) Traffic 12: 1196-210
MeSH Terms: Adult, Cell Membrane, Cells, Cultured, Child, Endocytosis, Endoplasmic Reticulum, Endosomes, Humans, Lung Diseases, Interstitial, Lysosomes, Mutation, Phospholipids, Protein Isoforms, Protein Precursors, Protein Transport, Pulmonary Surfactant-Associated Protein C, Recombinant Fusion Proteins, Transferrin, Transport Vesicles
Added January 20, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs.
Lawson WE, Cheng DS, Degryse AL, Tanjore H, Polosukhin VV, Xu XC, Newcomb DC, Jones BR, Roldan J, Lane KB, Morrisey EE, Beers MF, Yull FE, Blackwell TS
(2011) Proc Natl Acad Sci U S A 108: 10562-7
MeSH Terms: Animals, Apoptosis, Bleomycin, Endoplasmic Reticulum, Intercellular Signaling Peptides and Proteins, Lung, Mice, Mice, Transgenic, Mutation, Peptides, Pulmonary Fibrosis, Pulmonary Surfactant-Associated Protein C, Reverse Transcriptase Polymerase Chain Reaction, Tunicamycin
Added February 26, 2013
3 Communities
3 Members
0 Resources
14 MeSH Terms
Genetics in pulmonary fibrosis--familial cases provide clues to the pathogenesis of idiopathic pulmonary fibrosis.
Lawson WE, Loyd JE, Degryse AL
(2011) Am J Med Sci 341: 439-43
MeSH Terms: Cytoskeletal Proteins, Genetic Linkage, Humans, Idiopathic Pulmonary Fibrosis, Mutation, Pulmonary Fibrosis, Pulmonary Surfactant-Associated Protein A, Pulmonary Surfactant-Associated Protein C, RNA, Telomerase
Added March 5, 2014
0 Communities
2 Members
0 Resources
10 MeSH Terms
Idiopathic pulmonary fibrosis: a disorder of epithelial cell dysfunction.
Zoz DF, Lawson WE, Blackwell TS
(2011) Am J Med Sci 341: 435-8
MeSH Terms: Apoptosis, Epithelial Cells, Fibroblasts, Humans, Idiopathic Pulmonary Fibrosis, Mutation, Pulmonary Alveoli, Pulmonary Surfactant-Associated Protein A, Pulmonary Surfactant-Associated Protein C, Regeneration
Added March 5, 2014
1 Communities
2 Members
0 Resources
10 MeSH Terms
Identification of early interstitial lung disease in an individual with genetic variations in ABCA3 and SFTPC.
Crossno PF, Polosukhin VV, Blackwell TS, Johnson JE, Markin C, Moore PE, Worrell JA, Stahlman MT, Phillips JA, Loyd JE, Cogan JD, Lawson WE
(2010) Chest 137: 969-73
MeSH Terms: ATP-Binding Cassette Transporters, Adult, Female, Humans, Lung Diseases, Interstitial, Male, Middle Aged, Mutation, Pedigree, Pulmonary Surfactant-Associated Protein C
Added March 5, 2014
1 Communities
5 Members
0 Resources
10 MeSH Terms
Opposing regulation of human alveolar type II cell differentiation by nitric oxide and hyperoxia.
Johnston LC, Gonzales LW, Lightfoot RT, Guttentag SH, Ischiropoulos H
(2010) Pediatr Res 67: 521-5
MeSH Terms: Alveolar Epithelial Cells, Biomarkers, Cell Differentiation, Cell Hypoxia, Cells, Cultured, Cyclic GMP, Cyclic Nucleotide Phosphodiesterases, Type 5, Gene Expression Regulation, Gestational Age, Guanylate Cyclase, Humans, Nitric Oxide, Nuclear Proteins, Oxygen, Pulmonary Surfactant-Associated Protein B, Pulmonary Surfactant-Associated Protein C, RNA, Messenger, Receptors, Cytoplasmic and Nuclear, Signal Transduction, Soluble Guanylyl Cyclase, Thyroid Nuclear Factor 1, Time Factors, Transcription Factors
Added January 20, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms