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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 9702

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KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models.
West JD, Austin ED, Rizzi EM, Yan L, Tanjore H, Crabtree AL, Moore CS, Muthian G, Carrier EJ, Jacobson DA, Hamid R, Kendall PL, Majka S, Rathinasabapathy A
(2021) Int J Mol Sci 22:
MeSH Terms: Animals, Biomarkers, Case-Control Studies, Cytokines, Disease Models, Animal, Disease Susceptibility, Gene Expression Profiling, Genetic Predisposition to Disease, Humans, Hypoxia, Immunomodulation, Lymphocytes, Mice, Mice, Knockout, Models, Biological, Monocytes, Mutation, Nerve Tissue Proteins, Potassium Channels, Tandem Pore Domain, Pulmonary Arterial Hypertension, Transcriptome
Added June 14, 2021
0 Communities
1 Members
0 Resources
21 MeSH Terms
Genetic architecture of host proteins involved in SARS-CoV-2 infection.
Pietzner M, Wheeler E, Carrasco-Zanini J, Raffler J, Kerrison ND, Oerton E, Auyeung VPW, Luan J, Finan C, Casas JP, Ostroff R, Williams SA, Kastenmüller G, Ralser M, Gamazon ER, Wareham NJ, Hingorani AD, Langenberg C
(2020) Nat Commun 11: 6397
MeSH Terms: ABO Blood-Group System, Aptamers, Peptide, Blood Coagulation, COVID-19, Drug Delivery Systems, Female, Gene Expression Regulation, Host-Derived Cellular Factors, Host-Pathogen Interactions, Humans, Internet, Male, Middle Aged, Proteins, Quantitative Trait Loci, SARS-CoV-2
Added December 18, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Kidney epithelial targeted mitochondrial transcription factor A deficiency results in progressive mitochondrial depletion associated with severe cystic disease.
Ishii K, Kobayashi H, Taguchi K, Guan N, Li A, Tong C, Davidoff O, Tran PV, Sharma M, Chandel NS, Kapp ME, Fogo AB, Brooks CR, Haase VH
(2021) Kidney Int 99: 657-670
MeSH Terms: Animals, DNA-Binding Proteins, High Mobility Group Proteins, Humans, Kidney, Mice, Mitochondrial Proteins, Transcription Factors
Added November 10, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis.
Zhou D, Jiang Y, Zhong X, Cox NJ, Liu C, Gamazon ER
(2020) Nat Genet 52: 1239-1246
MeSH Terms: Animals, Gene Expression Profiling, Genetic Association Studies, Humans, Lipoproteins, LDL, Mendelian Randomization Analysis, Mice, Models, Genetic, Multifactorial Inheritance, Predictive Value of Tests
Added October 7, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin.
Kondo J, Huh WJ, Franklin JL, Heinrich MC, Rubin BP, Coffey RJ
(2020) J Pathol 252: 441-450
MeSH Terms: Animals, Biomarkers, Tumor, Disease Models, Animal, Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors, Mice, Muscle, Smooth, Mutation, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-kit, Receptor, Platelet-Derived Growth Factor alpha
Added September 25, 2020
1 Communities
0 Members
0 Resources
11 MeSH Terms
Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D.
DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wahl GM
(2020) Gastroenterology 159: 1866-1881.e8
MeSH Terms: Animals, Carcinoma, Pancreatic Ductal, Cell Transformation, Neoplastic, Ceruletide, Disease Models, Animal, Energy Metabolism, Fibrosis, Humans, Interleukins, Intramolecular Oxidoreductases, Mice, Transgenic, Mutation, Octamer Transcription Factors, Pancreas, Pancreatic Neoplasms, Pancreatitis, Prostaglandin D2, Proto-Oncogene Proteins p21(ras), Time Factors, Transcription Factors
Added March 13, 2021
0 Communities
1 Members
0 Resources
20 MeSH Terms
Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism.
Bayraktar EC, La K, Karpman K, Unlu G, Ozerdem C, Ritter DJ, Alwaseem H, Molina H, Hoffmann HH, Millner A, Atilla-Gokcumen GE, Gamazon ER, Rushing AR, Knapik EW, Basu S, Birsoy K
(2020) Nat Metab 2: 487-498
MeSH Terms: Animals, Cell Line, Cell Proliferation, Cholesterol, Gene Expression Regulation, Golgi Apparatus, Humans, Hyperlipidemias, Lipid Metabolism, Membrane Proteins, Proprotein Convertases, Serine Endopeptidases, Sterol Regulatory Element Binding Proteins, Zebrafish
Added September 9, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation.
Ho KH, Yang X, Osipovich AB, Cabrera O, Hayashi ML, Magnuson MA, Gu G, Kaverina I
(2020) Diabetes 69: 1936-1947
MeSH Terms: Animals, Cyclic AMP-Dependent Protein Kinases, Cyclin-Dependent Kinase 5, Glucose, Glycogen Synthase Kinase 3, Insulin Secretion, Insulin-Secreting Cells, Mice, Microtubules, Phosphorylation, Protein Kinase C, tau Proteins
Added July 2, 2020
2 Communities
4 Members
0 Resources
12 MeSH Terms
Osmotic Response of Dorsal Root Ganglion Neurons Expressing Wild-Type and Mutant KCC3 Transporters.
Flores B, Delpire E
(2020) Cell Physiol Biochem 54: 577-590
MeSH Terms: Animals, Axons, Cell Size, Corpus Callosum, Disease Models, Animal, Gain of Function Mutation, Ganglia, Spinal, Hereditary Sensory and Autonomic Neuropathies, Homeostasis, Humans, Membrane Transport Proteins, Mice, Mice, Knockout, Neurons, Osmotic Pressure, Symporters
Added June 30, 2020
1 Communities
0 Members
0 Resources
16 MeSH Terms
A social encounter drives gene expression changes linked to neuronal function, brain development, and related disorders in mice expressing the serotonin transporter Ala56 variant.
O'Reilly KC, Anacker AMJ, Rogers TD, Forsberg CG, Wang J, Zhang B, Blakely RD, Veenstra-VanderWeele J
(2020) Neurosci Lett 730: 135027
MeSH Terms: Animals, Autism Spectrum Disorder, Brain, Disease Models, Animal, Gene Expression, Male, Mice, Neurons, Serotonin, Serotonin Plasma Membrane Transport Proteins, Social Behavior
Added May 26, 2020
1 Communities
0 Members
0 Resources
11 MeSH Terms