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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 9 of 9

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mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.
Morrison MM, Young CD, Wang S, Sobolik T, Sanchez VM, Hicks DJ, Cook RS, Brantley-Sieders DM
(2015) PLoS Genet 11: e1005291
MeSH Terms: Animals, Carrier Proteins, Cell Line, Cell Movement, Cell Survival, Female, Mammary Glands, Animal, Mammary Neoplasms, Animal, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Inbred C57BL, Mice, Transgenic, Morphogenesis, Multiprotein Complexes, Neoplasm Invasiveness, Neuropeptides, Organ Culture Techniques, Phosphorylation, Protein Kinase C-alpha, Proto-Oncogene Proteins c-akt, Rapamycin-Insensitive Companion of mTOR Protein, TOR Serine-Threonine Kinases, rac1 GTP-Binding Protein
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
Wang S, Amato KR, Song W, Youngblood V, Lee K, Boothby M, Brantley-Sieders DM, Chen J
(2015) Mol Cell Biol 35: 1299-313
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Carrier Proteins, Cell Proliferation, Cells, Cultured, Endothelial Cells, Gene Deletion, Human Umbilical Vein Endothelial Cells, Humans, Mechanistic Target of Rapamycin Complex 2, Mice, Multiprotein Complexes, Neovascularization, Physiologic, Phosphorylation, Protein Kinase C-alpha, Proto-Oncogene Proteins c-akt, Rapamycin-Insensitive Companion of mTOR Protein, Regulatory-Associated Protein of mTOR, Signal Transduction, TOR Serine-Threonine Kinases, Vascular Endothelial Growth Factor A
Added February 15, 2016
0 Communities
1 Members
0 Resources
21 MeSH Terms
Onecut1 is essential for horizontal cell genesis and retinal integrity.
Wu F, Li R, Umino Y, Kaczynski TJ, Sapkota D, Li S, Xiang M, Fliesler SJ, Sherry DM, Gannon M, Solessio E, Mu X
(2013) J Neurosci 33: 13053-65, 13065a
MeSH Terms: Animals, Cell Count, Cell Differentiation, Cell Survival, Embryo, Mammalian, Eye Proteins, Gene Expression Regulation, Developmental, Green Fluorescent Proteins, Hepatocyte Nuclear Factor 6, Homeodomain Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Nerve Tissue Proteins, Neural Pathways, Neurogenesis, Neuroglia, Neurons, Protein Kinase C-alpha, Retina, Retinal Horizontal Cells, Synapses, Transcription Factors
Added November 25, 2014
1 Communities
0 Members
1 Resources
23 MeSH Terms
Regulation of phospholipase D activity and phosphatidic acid production after purinergic (P2Y6) receptor stimulation.
Scott SA, Xiang Y, Mathews TP, Cho HP, Myers DS, Armstrong MD, Tallman KA, O'Reilly MC, Lindsley CW, Brown HA
(2013) J Biol Chem 288: 20477-87
MeSH Terms: 1-Butanol, Blotting, Western, Cell Line, Tumor, Diacylglycerol Kinase, Diglycerides, Dose-Response Relationship, Drug, Enzyme Inhibitors, Humans, Hydrolysis, Isoenzymes, Mass Spectrometry, Models, Biological, Phosphatidic Acids, Phosphatidylcholines, Phospholipase C delta, Phospholipase D, Protein Kinase C-alpha, RNA Interference, Receptors, Purinergic P2, Signal Transduction, Uridine Diphosphate
Added March 7, 2014
1 Communities
2 Members
0 Resources
21 MeSH Terms
Migration of turkey muscle satellite cells is enhanced by the syndecan-4 cytoplasmic domain through the activation of RhoA.
Shin J, McFarland DC, Velleman SG
(2013) Mol Cell Biochem 375: 115-30
MeSH Terms: Animals, Avian Proteins, Cell Movement, Cells, Cultured, Enzyme Activation, Gene Knockdown Techniques, Male, Protein Kinase C-alpha, Protein Structure, Tertiary, RNA, Small Interfering, Satellite Cells, Skeletal Muscle, Syndecan-4, Turkey, rhoA GTP-Binding Protein
Added March 3, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCĪ± invasive signaling axis.
Hoshino D, Jourquin J, Emmons SW, Miller T, Goldgof M, Costello K, Tyson DR, Brown B, Lu Y, Prasad NK, Zhang B, Mills GB, Yarbrough WG, Quaranta V, Seiki M, Weaver AM
(2012) Sci Signal 5: ra66
MeSH Terms: Cell Line, Tumor, Focal Adhesions, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Head and Neck Neoplasms, Humans, Models, Biological, Neoplasm Invasiveness, Neoplasm Proteins, Phosphatidylinositol 3-Kinases, Phosphatidylinositol Phosphates, Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases, Phosphoric Monoester Hydrolases, Protein Kinase C-alpha, Signal Transduction
Added May 1, 2013
4 Communities
2 Members
0 Resources
15 MeSH Terms
Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin II-induced, PKC-alpha-dependent Akt activation in endosomes.
Nazarewicz RR, Salazar G, Patrushev N, San Martin A, Hilenski L, Xiong S, Alexander RW
(2011) J Biol Chem 286: 2886-95
MeSH Terms: Angiotensin II, Animals, Cells, Cultured, Endosomes, Enzyme Induction, Mitogen-Activated Protein Kinase 3, Muscle, Smooth, Vascular, Myocytes, Smooth Muscle, Phosphorylation, Protein Kinase C-alpha, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-akt, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Rats, Rats, Sprague-Dawley, TOR Serine-Threonine Kinases, Vasoconstrictor Agents, Vesicular Transport Proteins, p38 Mitogen-Activated Protein Kinases
Added June 9, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Pancreas-specific ablation of beta1 integrin induces tissue degeneration by disrupting acinar cell polarity.
Bombardelli L, Carpenter ES, Wu AP, Alston N, DelGiorno KE, Crawford HC
(2010) Gastroenterology 138: 2531-40, 2540.e1-4
MeSH Terms: Age Factors, Amylases, Animals, Cell Polarity, Ceruletide, Integrin beta1, Mice, Mice, Inbred C57BL, Necrosis, Pancreas, Exocrine, Protein Kinase C-alpha, Protein Kinase C-epsilon
Added March 13, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway.
Brown MV, Burnett PE, Denning MF, Reynolds AB
(2009) Exp Cell Res 315: 39-49
MeSH Terms: Catenins, Cell Adhesion Molecules, Cell Line, Cell Membrane, Enzyme Activation, Fibroblasts, Humans, Isoenzymes, Phosphoproteins, Phosphorylation, Phosphoserine, Platelet-Derived Growth Factor, Protein Kinase C-alpha, Receptors, G-Protein-Coupled, Receptors, Platelet-Derived Growth Factor
Added March 5, 2014
1 Communities
1 Members
0 Resources
15 MeSH Terms