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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 213

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Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis.
Linton MF, Moslehi JJ, Babaev VR
(2019) Int J Mol Sci 20:
MeSH Terms: Animals, Apoptosis, Atherosclerosis, Blood Cells, Cell Survival, Humans, Macrophage Activation, Macrophages, Phosphatidylinositol 3-Kinases, Protein Isoforms, Proto-Oncogene Proteins c-akt, Signal Transduction
Added November 12, 2019
0 Communities
1 Members
0 Resources
12 MeSH Terms
Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.
Babaev VR, Ding L, Zhang Y, May JM, Ramsey SA, Vickers KC, Linton MF
(2019) Arterioscler Thromb Vasc Biol 39: 156-169
MeSH Terms: Animals, Atherosclerosis, Cell Survival, Female, Hematopoietic System, Macrophages, Male, Mice, Mice, Inbred C57BL, Monocytes, Protein Isoforms, Proto-Oncogene Proteins c-akt, Receptors, LDL
Added April 10, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
Discovery of Novel Central Nervous System Penetrant Metabotropic Glutamate Receptor Subtype 2 (mGlu) Negative Allosteric Modulators (NAMs) Based on Functionalized Pyrazolo[1,5- a]pyrimidine-5-carboxamide and Thieno[3,2- b]pyridine-5-carboxamide Cores.
Childress ES, Wieting JM, Felts AS, Breiner MM, Long MF, Luscombe VB, Rodriguez AL, Cho HP, Blobaum AL, Niswender CM, Emmitte KA, Conn PJ, Lindsley CW
(2019) J Med Chem 62: 378-384
MeSH Terms: Allosteric Regulation, Amides, Animals, Central Nervous System, Drug Evaluation, Preclinical, Half-Life, Humans, Inhibitory Concentration 50, Protein Isoforms, Pyrazoles, Pyridines, Pyrimidines, Rats, Receptors, Metabotropic Glutamate, Structure-Activity Relationship
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
The Role of Aquaporins in Ocular Lens Homeostasis.
Schey KL, Petrova RS, Gletten RB, Donaldson PJ
(2017) Int J Mol Sci 18:
MeSH Terms: Animals, Aquaporins, Biological Transport, Active, Eye Proteins, Homeostasis, Humans, Lens, Crystalline, Permeability, Protein Isoforms, Water
Added April 3, 2018
0 Communities
1 Members
0 Resources
10 MeSH Terms
UNC-45a promotes myosin folding and stress fiber assembly.
Lehtimäki JI, Fenix AM, Kotila TM, Balistreri G, Paavolainen L, Varjosalo M, Burnette DT, Lappalainen P
(2017) J Cell Biol 216: 4053-4072
MeSH Terms: Actomyosin, Cell Adhesion, Cell Line, Tumor, Cell Movement, Cell Polarity, Gene Expression, Humans, Intracellular Signaling Peptides and Proteins, Myosin Type II, Osteoblasts, Proteasome Endopeptidase Complex, Protein Folding, Protein Isoforms, Stress Fibers, Tetratricopeptide Repeat
Added March 14, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
Implications of the N-terminal heterogeneity for the neuronal K-Cl cotransporter KCC2 function.
Markkanen M, Ludwig A, Khirug S, Pryazhnikov E, Soni S, Khiroug L, Delpire E, Rivera C, Airaksinen MS, Uvarov P
(2017) Brain Res 1675: 87-101
MeSH Terms: Amino Acid Sequence, Animals, Female, HEK293 Cells, Humans, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Neurons, Protein Isoforms, Rats, Symporters
Added April 3, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Associations of Vitamin D-Binding Globulin and Bioavailable Vitamin D Concentrations With Coronary Heart Disease Events: The Multi-Ethnic Study of Atherosclerosis (MESA).
Robinson-Cohen C, Zelnick LR, Hoofnagle AN, Lutsey PL, Burke G, Michos ED, Shea SJC, Tracy R, Siscovick DS, Psaty B, Kestenbaum B, de Boer IH
(2017) J Clin Endocrinol Metab 102: 3075-3084
MeSH Terms: African Americans, Aged, Aged, 80 and over, Asian Continental Ancestry Group, Biological Availability, Case-Control Studies, Coronary Disease, European Continental Ancestry Group, Female, Hispanic Americans, Humans, Male, Mass Spectrometry, Middle Aged, Proportional Hazards Models, Protein Isoforms, Risk Factors, United States, Vitamin D, Vitamin D-Binding Protein
Added September 19, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms
The nature and biology of basement membranes.
Pozzi A, Yurchenco PD, Iozzo RV
(2017) Matrix Biol 57-58: 1-11
MeSH Terms: Agrin, Animals, Basement Membrane, Bone Diseases, Developmental, Collagen Type IV, Diabetic Nephropathies, Extracellular Matrix, Gene Expression Regulation, Heparan Sulfate Proteoglycans, Humans, Laminin, Lupus Nephritis, Mechanotransduction, Cellular, Membrane Glycoproteins, Mutation, Protein Isoforms
Added March 26, 2017
0 Communities
0 Members
1 Resources
16 MeSH Terms
Regulation of KCNQ/Kv7 family voltage-gated K channels by lipids.
Taylor KC, Sanders CR
(2017) Biochim Biophys Acta Biomembr 1859: 586-597
MeSH Terms: Amino Acid Sequence, Binding Sites, Cell Membrane, Epilepsy, Benign Neonatal, Fatty Acids, Unsaturated, Hearing Loss, Bilateral, Humans, Hydrophobic and Hydrophilic Interactions, KCNQ1 Potassium Channel, Long QT Syndrome, Membrane Lipids, Models, Molecular, Phosphatidylinositol 4,5-Diphosphate, Protein Binding, Protein Isoforms, Protein Structure, Secondary
Added November 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
High-Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML.
Zhao Y, Liu Q, Acharya P, Stengel KR, Sheng Q, Zhou X, Kwak H, Fischer MA, Bradner JE, Strickland SA, Mohan SR, Savona MR, Venters BJ, Zhou MM, Lis JT, Hiebert SW
(2016) Cell Rep 16: 2003-16
MeSH Terms: Antineoplastic Agents, Azepines, Cell Line, Tumor, Chromosomes, Human, Pair 21, Chromosomes, Human, Pair 8, Clustered Regularly Interspaced Short Palindromic Repeats, DNA-Directed RNA Polymerases, Drug Resistance, Neoplasm, Enhancer Elements, Genetic, Gene Expression Regulation, Leukemic, High-Throughput Nucleotide Sequencing, Humans, Leukemia, Myeloid, Acute, MicroRNAs, Multigene Family, Myeloid Cell Leukemia Sequence 1 Protein, Promoter Regions, Genetic, Protein Isoforms, Proteins, Proto-Oncogene Proteins c-kit, Transcription, Genetic, Translocation, Genetic, Triazoles
Added April 6, 2017
0 Communities
1 Members
0 Resources
23 MeSH Terms