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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 139

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Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning.
Penn WD, McKee AG, Kuntz CP, Woods H, Nash V, Gruenhagen TC, Roushar FJ, Chandak M, Hemmerich C, Rusch DB, Meiler J, Schlebach JP
(2020) Sci Adv 6: eaay7505
MeSH Terms: Cell Membrane, Gene Expression, HEK293 Cells, Humans, Hydrophobic and Hydrophilic Interactions, Lipid Bilayers, Models, Molecular, Mutation, Protein Domains, Protein Folding, Protein Structure, Secondary, Recombinant Proteins, Rhodopsin, Solubility, Thermodynamics
Added March 21, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Rapid Simulation of Unprocessed DEER Decay Data for Protein Fold Prediction.
Del Alamo D, Tessmer MH, Stein RA, Feix JB, Mchaourab HS, Meiler J
(2020) Biophys J 118: 366-375
MeSH Terms: Electron Spin Resonance Spectroscopy, Monte Carlo Method, Nitrogen Oxides, Protein Folding, Spin Labels, Time Factors
Added March 21, 2020
0 Communities
1 Members
0 Resources
6 MeSH Terms
Protein structure prediction using sparse NOE and RDC restraints with Rosetta in CASP13.
Kuenze G, Meiler J
(2019) Proteins 87: 1341-1350
MeSH Terms: Computational Biology, Magnetic Resonance Spectroscopy, Models, Molecular, Protein Conformation, Protein Folding, Proteins, Software
Added March 21, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis.
Marinko JT, Huang H, Penn WD, Capra JA, Schlebach JP, Sanders CR
(2019) Chem Rev 119: 5537-5606
MeSH Terms: Humans, Kinetics, Membrane Proteins, Models, Molecular, Protein Conformation, Protein Folding, Protein Stability, Proteostasis, Proteostasis Deficiencies, Thermodynamics
Added March 3, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis.
Roushar FJ, Gruenhagen TC, Penn WD, Li B, Meiler J, Jastrzebska B, Schlebach JP
(2019) J Am Chem Soc 141: 204-215
MeSH Terms: Humans, Models, Molecular, Protein Conformation, Protein Engineering, Protein Folding, Proteostasis, Rhodopsin, Thermodynamics
Added March 21, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations.
Huang H, Kuenze G, Smith JA, Taylor KC, Duran AM, Hadziselimovic A, Meiler J, Vanoye CG, George AL, Sanders CR
(2018) Sci Adv 4: eaar2631
MeSH Terms: Cell Membrane, HEK293 Cells, Humans, KCNQ1 Potassium Channel, Leupeptins, Long QT Syndrome, Loss of Function Mutation, Magnetic Resonance Spectroscopy, Mutant Proteins, Mutation, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Protein Domains, Protein Folding, Protein Structure, Secondary, Proteolysis
Added March 14, 2018
0 Communities
3 Members
0 Resources
16 MeSH Terms
Integrated Structural Biology for α-Helical Membrane Protein Structure Determination.
Xia Y, Fischer AW, Teixeira P, Weiner B, Meiler J
(2018) Structure 26: 657-666.e2
MeSH Terms: Algorithms, Binding Sites, Electron Spin Resonance Spectroscopy, Humans, Membrane Proteins, Microscopy, Electron, Models, Molecular, Monte Carlo Method, Nuclear Magnetic Resonance, Biomolecular, Protein Binding, Protein Conformation, alpha-Helical, Protein Folding, Protein Interaction Domains and Motifs, Rhodopsin, Thermodynamics
Added March 17, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
UNC-45a promotes myosin folding and stress fiber assembly.
Lehtimäki JI, Fenix AM, Kotila TM, Balistreri G, Paavolainen L, Varjosalo M, Burnette DT, Lappalainen P
(2017) J Cell Biol 216: 4053-4072
MeSH Terms: Actomyosin, Cell Adhesion, Cell Line, Tumor, Cell Movement, Cell Polarity, Gene Expression, Humans, Intracellular Signaling Peptides and Proteins, Myosin Type II, Osteoblasts, Proteasome Endopeptidase Complex, Protein Folding, Protein Isoforms, Stress Fibers, Tetratricopeptide Repeat
Added March 14, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
Finding the needle in the haystack: towards solving the protein-folding problem computationally.
Li B, Fooksa M, Heinze S, Meiler J
(2018) Crit Rev Biochem Mol Biol 53: 1-28
MeSH Terms: Algorithms, Animals, Humans, Kinetics, Molecular Dynamics Simulation, Protein Folding, Protein Structure, Tertiary, Proteins, Thermodynamics
Added March 17, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.
Schonhoft JD, Monteiro C, Plate L, Eisele YS, Kelly JM, Boland D, Parker CG, Cravatt BF, Teruya S, Helmke S, Maurer M, Berk J, Sekijima Y, Novais M, Coelho T, Powers ET, Kelly JW
(2017) Sci Transl Med 9:
MeSH Terms: Amyloidosis, Familial, Benzoxazoles, Case-Control Studies, Cross-Linking Reagents, Diazomethane, Genotype, Humans, Ions, Light, Molecular Probes, Molecular Weight, Peptides, Prealbumin, Protein Folding, Protein Multimerization, Protein Structure, Secondary, Proteolysis, Proteomics, Solubility
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms