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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 48

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Broad dengue neutralization in mosquitoes expressing an engineered antibody.
Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Crowe JE, Paradkar PN, Akbari OS
(2020) PLoS Pathog 16: e1008103
MeSH Terms: Aedes, Animals, Antibodies, Viral, Broadly Neutralizing Antibodies, Dengue Virus, Female, Humans, Male, Protein Engineering, Single-Chain Antibodies
Added March 31, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications.
Li Z, Jiang Y, Guengerich FP, Ma L, Li S, Zhang W
(2020) J Biol Chem 295: 833-849
MeSH Terms: Biocatalysis, Biotechnology, Cytochrome P-450 Enzyme System, Metabolic Engineering, Protein Engineering, Steroids, Substrate Specificity, Xenobiotics
Added March 3, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Contribution of Cotranslational Folding Defects to Membrane Protein Homeostasis.
Roushar FJ, Gruenhagen TC, Penn WD, Li B, Meiler J, Jastrzebska B, Schlebach JP
(2019) J Am Chem Soc 141: 204-215
MeSH Terms: Humans, Models, Molecular, Protein Conformation, Protein Engineering, Protein Folding, Proteostasis, Rhodopsin, Thermodynamics
Added March 21, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
A critical analysis of computational protein design with sparse residue interaction graphs.
Jain S, Jou JD, Georgiev IS, Donald BR
(2017) PLoS Comput Biol 13: e1005346
MeSH Terms: Algorithms, Amino Acid Sequence, Animals, Computational Biology, Computer Graphics, Humans, Models, Molecular, Protein Conformation, Protein Engineering, Proteins, Software, Thermodynamics
Added May 3, 2017
0 Communities
1 Members
0 Resources
12 MeSH Terms
Reprogramming cell fate with a genome-scale library of artificial transcription factors.
Eguchi A, Wleklinski MJ, Spurgat MC, Heiderscheit EA, Kropornicka AS, Vu CK, Bhimsaria D, Swanson SA, Stewart R, Ramanathan P, Kamp TJ, Slukvin I, Thomson JA, Dutton JR, Ansari AZ
(2016) Proc Natl Acad Sci U S A 113: E8257-E8266
MeSH Terms: Animals, Binding Sites, Cell Lineage, Cellular Reprogramming, Chaperonin Containing TCP-1, Epigenesis, Genetic, Fibroblasts, Gene Expression Regulation, Neoplastic, Gene Regulatory Networks, Genomic Library, HEK293 Cells, Humans, Mice, Protein Domains, Protein Engineering, Sequence Analysis, RNA, Transcription Factors, Transcription, Genetic, Zinc Fingers
Added September 5, 2017
0 Communities
1 Members
0 Resources
19 MeSH Terms
Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Joyce MG, Zhang B, Ou L, Chen M, Chuang GY, Druz A, Kong WP, Lai YT, Rundlet EJ, Tsybovsky Y, Yang Y, Georgiev IS, Guttman M, Lees CR, Pancera M, Sastry M, Soto C, Stewart-Jones GBE, Thomas PV, Van Galen JG, Baxa U, Lee KK, Mascola JR, Graham BS, Kwong PD
(2016) Nat Struct Mol Biol 23: 811-820
MeSH Terms: Animals, Crystallography, X-Ray, Female, Glycoproteins, HEK293 Cells, Humans, Male, Mice, Inbred C57BL, Models, Molecular, Protein Engineering, Protein Stability, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses, Vaccination, Viral Fusion Proteins, Viral Vaccines
Added May 3, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
Design of Protein Multi-specificity Using an Independent Sequence Search Reduces the Barrier to Low Energy Sequences.
Sevy AM, Jacobs TM, Crowe JE, Meiler J
(2015) PLoS Comput Biol 11: e1004300
MeSH Terms: Algorithms, Amino Acid Sequence, Binding Sites, Computer Simulation, Directed Molecular Evolution, Drug Design, Energy Transfer, Models, Chemical, Models, Molecular, Molecular Sequence Data, Protein Binding, Protein Engineering, Proteins, Sequence Analysis, Protein, Structure-Activity Relationship, Thermodynamics
Added January 26, 2016
1 Communities
3 Members
0 Resources
16 MeSH Terms
An Fc engineering approach that modulates antibody-dependent cytokine release without altering cell-killing functions.
Kinder M, Greenplate AR, Strohl WR, Jordan RE, Brezski RJ
(2015) MAbs 7: 494-504
MeSH Terms: Antibodies, Monoclonal, Antibodies, Neoplasm, Antibody-Dependent Cell Cytotoxicity, Cell Line, Tumor, Cytokines, Humans, Immunoglobulin Fc Fragments, Macrophages, Neoplasms, Protein Engineering, Tumor Microenvironment
Added April 22, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
Beyond traditional pharmacology: new tools and approaches.
Gurevich EV, Gurevich VV
(2015) Br J Pharmacol 172: 3229-41
MeSH Terms: Animals, Biological Products, Cell- and Tissue-Based Therapy, Genetic Therapy, Humans, Pharmacology, Protein Engineering, Signal Transduction
Added February 12, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
Antibody engineering and therapeutics, The Annual Meeting of the Antibody Society: December 8-12, 2013, Huntington Beach, CA.
Almagro JC, Gilliland GL, Breden F, Scott JK, Sok D, Pauthner M, Reichert JM, Helguera G, Andrabi R, Mabry R, Bléry M, Voss JE, Laurén J, Abuqayyas L, Barghorn S, Ben-Jacob E, Crowe JE, Huston JS, Johnston SA, Krauland E, Lund-Johansen F, Marasco WA, Parren PW, Xu KY
(2014) MAbs 6: 577-618
MeSH Terms: Animals, Antibodies, Directed Molecular Evolution, Drug Design, Humans, Immunotherapy, Neoplasms, Protein Engineering, Societies, Scientific, Systems Biology
Added March 20, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms