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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 97

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Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations.
Huang H, Kuenze G, Smith JA, Taylor KC, Duran AM, Hadziselimovic A, Meiler J, Vanoye CG, George AL, Sanders CR
(2018) Sci Adv 4: eaar2631
MeSH Terms: Cell Membrane, HEK293 Cells, Humans, KCNQ1 Potassium Channel, Leupeptins, Long QT Syndrome, Loss of Function Mutation, Magnetic Resonance Spectroscopy, Mutant Proteins, Mutation, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Protein Domains, Protein Folding, Protein Structure, Secondary, Proteolysis
Added March 14, 2018
0 Communities
3 Members
0 Resources
16 MeSH Terms
UNC-45a promotes myosin folding and stress fiber assembly.
Lehtimäki JI, Fenix AM, Kotila TM, Balistreri G, Paavolainen L, Varjosalo M, Burnette DT, Lappalainen P
(2017) J Cell Biol 216: 4053-4072
MeSH Terms: Actomyosin, Cell Adhesion, Cell Line, Tumor, Cell Movement, Cell Polarity, Gene Expression, Humans, Intracellular Signaling Peptides and Proteins, Myosin Type II, Osteoblasts, Proteasome Endopeptidase Complex, Protein Folding, Protein Isoforms, Stress Fibers, Tetratricopeptide Repeat
Added March 14, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.
Ando K, Shah AK, Sachdev V, Kleinstiver BP, Taylor-Parker J, Welch MM, Hu Y, Salgia R, White FM, Parvin JD, Ozonoff A, Rameh LE, Joung JK, Bharti AK
(2017) Oncotarget 8: 43733-43751
MeSH Terms: BRCA1 Protein, Camptothecin, Cell Line, Tumor, DNA Topoisomerases, Type I, DNA-Binding Proteins, Drug Resistance, Neoplasm, Gene Editing, Humans, Ku Autoantigen, Multiprotein Complexes, PTEN Phosphohydrolase, Phosphorylation, Proteasome Endopeptidase Complex, Protein Binding, Protein Kinase C, Proteolysis, RNA Interference, Topoisomerase I Inhibitors, Ubiquitin
Added November 26, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Bortezomib augments lymphocyte stimulatory cytokine signaling in the tumor microenvironment to sustain CD8+T cell antitumor function.
Pellom ST, Dudimah DF, Thounaojam MC, Uzhachenko RV, Singhal A, Richmond A, Shanker A
(2017) Oncotarget 8: 8604-8621
MeSH Terms: Adenocarcinoma, Animals, Antineoplastic Agents, Bortezomib, Breast Neoplasms, CD8-Positive T-Lymphocytes, Cell Line, Tumor, Cytokines, Female, Fibrosarcoma, Kidney Neoplasms, Lung Neoplasms, Lymphocytes, Tumor-Infiltrating, Mice, Inbred BALB C, Mice, Transgenic, Phosphatidylinositol 3-Kinase, Proteasome Endopeptidase Complex, Proteasome Inhibitors, Proto-Oncogene Proteins c-akt, Receptors, Cytokine, STAT5 Transcription Factor, Signal Transduction, Tumor Escape, Tumor Microenvironment
Added March 14, 2017
2 Communities
1 Members
0 Resources
24 MeSH Terms
Tyrosine phosphorylation modulates mitochondrial chaperonin Hsp60 and delays rotavirus NSP4-mediated apoptotic signaling in host cells.
Chattopadhyay S, Mukherjee A, Patra U, Bhowmick R, Basak T, Sengupta S, Chawla-Sarkar M
(2017) Cell Microbiol 19:
MeSH Terms: Apoptosis, Cell Line, Chaperonin 60, Glycoproteins, Host-Pathogen Interactions, Humans, Phosphorylation, Proteasome Endopeptidase Complex, Protein Processing, Post-Translational, Proteolysis, Rotavirus, Signal Transduction, Time Factors, Toxins, Biological, Tyrosine, Viral Nonstructural Proteins
Added November 3, 2017
0 Communities
1 Members
0 Resources
16 MeSH Terms
Interaction of Gcn4 with target gene chromatin is modulated by proteasome function.
Howard GC, Tansey WP
(2016) Mol Biol Cell 27: 2735-41
MeSH Terms: Adenosine Triphosphatases, Basic-Leucine Zipper Transcription Factors, Cell Cycle Proteins, Chromatin, DNA-Binding Proteins, Molecular Chaperones, Proteasome Endopeptidase Complex, Proteolysis, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Transcription Factors, Transcriptional Activation, Ubiquitin, Ubiquitination, Valosin Containing Protein
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.
Zhao W, Vaithiyalingam S, San Filippo J, Maranon DG, Jimenez-Sainz J, Fontenay GV, Kwon Y, Leung SG, Lu L, Jensen RB, Chazin WJ, Wiese C, Sung P
(2015) Mol Cell 59: 176-87
MeSH Terms: Amino Acid Substitution, BRCA2 Protein, Breast Neoplasms, Cell Line, Female, HeLa Cells, Homologous Recombination, Humans, Models, Biological, Molecular Mimicry, Mutagenesis, Site-Directed, Nuclear Magnetic Resonance, Biomolecular, Proteasome Endopeptidase Complex, Protein Subunits, Rad51 Recombinase, Recombinant Proteins, Replication Protein A
Added February 5, 2016
1 Communities
2 Members
0 Resources
17 MeSH Terms
Functions of the proteasome on chromatin.
McCann TS, Tansey WP
(2014) Biomolecules 4: 1026-44
MeSH Terms: Animals, Chromatin, Humans, Proteasome Endopeptidase Complex, RNA, Messenger, Transcription, Genetic
Added February 12, 2015
0 Communities
1 Members
0 Resources
6 MeSH Terms
Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells.
Sancho R, Gruber R, Gu G, Behrens A
(2014) Cell Stem Cell 15: 139-53
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Differentiation, Cell Line, Tumor, Cell Lineage, F-Box Proteins, F-Box-WD Repeat-Containing Protein 7, Gene Deletion, Gene Expression Profiling, Gene Expression Regulation, Developmental, Glucagon-Secreting Cells, Glucose, HEK293 Cells, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice, Multipotent Stem Cells, Nerve Tissue Proteins, Pancreatic Ducts, Proteasome Endopeptidase Complex, Regeneration, Somatostatin-Secreting Cells, Ubiquitin-Protein Ligases, Ubiquitination
Added January 23, 2015
1 Communities
1 Members
0 Resources
26 MeSH Terms
The type II deiodinase is retrotranslocated to the cytoplasm and proteasomes via p97/Atx3 complex.
Arrojo E Drigo R, Egri P, Jo S, Gereben B, Bianco AC
(2013) Mol Endocrinol 27: 2105-15
MeSH Terms: Adenosine Triphosphatases, Ataxin-3, Cytoplasm, Endoplasmic Reticulum, Endoplasmic Reticulum-Associated Degradation, Enzyme Stability, HEK293 Cells, Humans, Iodide Peroxidase, Lysine, Nerve Tissue Proteins, Nuclear Proteins, Proteasome Endopeptidase Complex, Protein Transport, Repressor Proteins, Substrate Specificity, Ubiquitin, Ubiquitination
Added April 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms