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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 69

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Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D.
DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wahl GM
(2020) Gastroenterology 159: 1866-1881.e8
MeSH Terms: Animals, Carcinoma, Pancreatic Ductal, Cell Transformation, Neoplastic, Ceruletide, Disease Models, Animal, Energy Metabolism, Fibrosis, Humans, Interleukins, Intramolecular Oxidoreductases, Mice, Transgenic, Mutation, Octamer Transcription Factors, Pancreas, Pancreatic Neoplasms, Pancreatitis, Prostaglandin D2, Proto-Oncogene Proteins p21(ras), Time Factors, Transcription Factors
Added March 13, 2021
0 Communities
1 Members
0 Resources
20 MeSH Terms
Levuglandin forms adducts with histone h4 in a cyclooxygenase-2-dependent manner, altering its interaction with DNA.
Carrier EJ, Zagol-Ikapitte I, Amarnath V, Boutaud O, Oates JA
(2014) Biochemistry 53: 2436-41
MeSH Terms: Chromatography, Liquid, Cyclooxygenase 2, DNA, Histones, Mass Spectrometry, Prostaglandin D2, Prostaglandins E, Solubility
Added January 22, 2015
0 Communities
2 Members
0 Resources
8 MeSH Terms
Nrf2 is essential for the expression of lipocalin-prostaglandin D synthase induced by prostaglandin D2.
Kim KH, Sadikot RT, Xiao L, Christman JW, Freeman ML, Chan JY, Oh YK, Blackwell TS, Joo M
(2013) Free Radic Biol Med 65: 1134-1142
MeSH Terms: Amino Acid Sequence, Animals, Base Sequence, Binding Sites, Cell Line, Cyclooxygenase 2, Intramolecular Oxidoreductases, Lipocalins, Lipopolysaccharides, Lung, Macrophages, Mice, Mice, Inbred C57BL, Mice, Knockout, NF-E2-Related Factor 2, Neutrophil Infiltration, Neutrophils, Pneumonia, Promoter Regions, Genetic, Prostaglandin D2, Protein Binding, RNA Interference, RNA, Small Interfering, Sequence Analysis, DNA, Toll-Like Receptor 4
Added March 7, 2014
1 Communities
2 Members
0 Resources
25 MeSH Terms
Human platelets generate phospholipid-esterified prostaglandins via cyclooxygenase-1 that are inhibited by low dose aspirin supplementation.
Aldrovandi M, Hammond VJ, Podmore H, Hornshaw M, Clark SR, Marnett LJ, Slatter DA, Murphy RC, Collins PW, O'Donnell VB
(2013) J Lipid Res 54: 3085-97
MeSH Terms: Aspirin, Blood Platelets, Calcium, Cyclooxygenase 1, Cyclooxygenase Inhibitors, Dinoprostone, Dose-Response Relationship, Drug, Esterification, Feedback, Physiological, Humans, Intracellular Space, MAP Kinase Kinase 1, Phosphatidylethanolamines, Phospholipids, Platelet Activation, Prostaglandin D2, Prostaglandins, Protein Kinase C, Receptor, PAR-1, Thrombin, src-Family Kinases
Added March 7, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Quantification of major urinary metabolites of PGE2 and PGD2 in cystic fibrosis: correlation with disease severity.
Jabr S, Gartner S, Milne GL, Roca-Ferrer J, Casas J, Moreno A, Gelpí E, Picado C
(2013) Prostaglandins Leukot Essent Fatty Acids 89: 121-6
MeSH Terms: Adolescent, Child, Cystic Fibrosis, Dinoprostone, Female, Humans, Male, Prostaglandin D2
Added March 26, 2014
1 Communities
1 Members
0 Resources
8 MeSH Terms
Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception.
Weng Y, Batista-Schepman PA, Barabas ME, Harris EQ, Dinsmore TB, Kossyreva EA, Foshage AM, Wang MH, Schwab MJ, Wang VM, Stucky CL, Story GM
(2012) Mol Pain 8: 75
MeSH Terms: Animals, Ganglia, Spinal, Male, Mice, Mice, Knockout, Mustard Plant, Nociception, Plant Oils, Prostaglandin D2, Prostaglandins, TRPA1 Cation Channel, Transient Receptor Potential Channels
Added May 15, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2).
Prage EB, Morgenstern R, Jakobsson PJ, Stec DF, Voehler MW, Armstrong RN
(2012) Biochemistry 51: 2348-56
MeSH Terms: Anti-Inflammatory Agents, Binding Sites, Glutathione, Humans, Inflammation, Intramolecular Oxidoreductases, Mass Spectrometry, Microsomes, Prostaglandin D2, Prostaglandin-E Synthases
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Amniotic fluid eicosanoids in preterm and term births: effects of risk factors for spontaneous preterm labor.
Menon R, Fortunato SJ, Milne GL, Brou L, Carnevale C, Sanchez SC, Hubbard L, Lappas M, Drobek CO, Taylor RN
(2011) Obstet Gynecol 118: 121-134
MeSH Terms: Amniotic Fluid, Apgar Score, Arachidonic Acid, Case-Control Studies, Cross-Sectional Studies, Dinoprost, Dinoprostone, F2-Isoprostanes, Female, Humans, Lipid Peroxidation, Mass Spectrometry, Obstetric Labor, Premature, Oxidative Stress, Pregnancy, Prostaglandin D2, Smoking, Term Birth
Added March 26, 2014
1 Communities
1 Members
0 Resources
18 MeSH Terms
Nonenzymatic free radical-catalyzed generation of 15-deoxy-Δ(12,14)-prostaglandin J₂-like compounds (deoxy-J₂-isoprostanes) in vivo.
Hardy KD, Cox BE, Milne GL, Yin H, Roberts LJ
(2011) J Lipid Res 52: 113-24
MeSH Terms: Animals, Arachidonic Acid, Catalysis, Free Radicals, Glutathione, Humans, Isoprostanes, Kinetics, Ligands, Liver, Male, Oxidative Stress, Prostaglandin D2, Rats, Rats, Sprague-Dawley
Added March 26, 2014
1 Communities
1 Members
0 Resources
15 MeSH Terms
Lipopolysaccharide-dependent interaction between PU.1 and c-Jun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages.
Joo M, Kwon M, Cho YJ, Hu N, Pedchenko TV, Sadikot RT, Blackwell TS, Christman JW
(2009) Am J Physiol Lung Cell Mol Physiol 296: L771-9
MeSH Terms: Animals, Base Sequence, Binding Sites, Cell Line, Female, Humans, Intramolecular Oxidoreductases, JNK Mitogen-Activated Protein Kinases, Lipocalins, Lipopolysaccharides, Macrophages, Male, Mice, Mice, Inbred C57BL, Models, Biological, Molecular Sequence Data, Promoter Regions, Genetic, Prostaglandin D2, Protein Binding, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-jun, Trans-Activators, Transcriptional Activation, p38 Mitogen-Activated Protein Kinases
Added March 5, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms