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Results: 1 to 10 of 34

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Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration.
Aamodt KI, Aramandla R, Brown JJ, Fiaschi-Taesch N, Wang P, Stewart AF, Brissova M, Powers AC
(2016) Am J Physiol Endocrinol Metab 311: E859-E868
MeSH Terms: Activins, Adenosine, Adenosine A2 Receptor Agonists, Adenosine-5'-(N-ethylcarboxamide), Adult, Automation, Cell Culture Techniques, Cell Proliferation, Drug Evaluation, Preclinical, Erythropoietin, Exenatide, Female, GABA Agents, Harmine, Humans, Incretins, Insulin-Secreting Cells, Male, Middle Aged, Monoamine Oxidase Inhibitors, Myostatin, Nucleosides, Peptides, Platelet-Derived Growth Factor, Prolactin, Regeneration, Serotonin, Serotonin Receptor Agonists, Vasodilator Agents, Venoms, Young Adult, gamma-Aminobutyric Acid
Added April 26, 2017
0 Communities
2 Members
0 Resources
32 MeSH Terms
Gestational Diabetes Mellitus From Inactivation of Prolactin Receptor and MafB in Islet β-Cells.
Banerjee RR, Cyphert HA, Walker EM, Chakravarthy H, Peiris H, Gu X, Liu Y, Conrad E, Goodrich L, Stein RW, Kim SK
(2016) Diabetes 65: 2331-41
MeSH Terms: Animals, Cell Proliferation, Cells, Cultured, Cyclin A2, Cyclin B1, Cyclin B2, Cyclin D1, Cyclin D2, Diabetes, Gestational, Female, Forkhead Box Protein M1, Insulin, Insulin-Secreting Cells, MafB Transcription Factor, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Pregnancy, Receptors, Prolactin, Serotonin, Signal Transduction, Tryptophan Hydroxylase
Added September 19, 2016
0 Communities
1 Members
0 Resources
23 MeSH Terms
Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.
Brouwers B, de Faudeur G, Osipovich AB, Goyvaerts L, Lemaire K, Boesmans L, Cauwelier EJ, Granvik M, Pruniau VP, Van Lommel L, Van Schoors J, Stancill JS, Smolders I, Goffin V, Binart N, in't Veld P, Declercq J, Magnuson MA, Creemers JW, Schuit F, Schraenen A
(2014) Cell Metab 20: 979-90
MeSH Terms: Animals, Female, Human Growth Hormone, Humans, Islets of Langerhans, Male, Mice, Mice, Transgenic, Receptors, Prolactin, Tryptophan Hydroxylase
Added December 11, 2014
2 Communities
2 Members
0 Resources
10 MeSH Terms
The activity of prolactin releasing peptide correlates with its helicity.
Deluca SH, Rathmann D, Beck-Sickinger AG, Meiler J
(2013) Biopolymers 99: 314-25
MeSH Terms: Amino Acid Sequence, Animals, Binding Sites, COS Cells, Cell Line, Tumor, Chlorocebus aethiops, Circular Dichroism, Humans, Hydrogen-Ion Concentration, Magnetic Resonance Spectroscopy, Models, Molecular, Molecular Sequence Data, Mutation, Prolactin-Releasing Hormone, Protein Binding, Protein Conformation, Protein Stability, Protein Structure, Secondary, Receptors, Neuropeptide, Signal Transduction, Sodium Dodecyl Sulfate, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Temperature, Trifluoroacetic Acid
Added January 24, 2015
1 Communities
1 Members
0 Resources
24 MeSH Terms
Ligand-mimicking receptor variant discloses binding and activation mode of prolactin-releasing peptide.
Rathmann D, Lindner D, DeLuca SH, Kaufmann KW, Meiler J, Beck-Sickinger AG
(2012) J Biol Chem 287: 32181-94
MeSH Terms: Amino Acid Sequence, Animals, COS Cells, Chlorocebus aethiops, Cloning, Molecular, Drug Design, Genetic Vectors, HEK293 Cells, Humans, Inhibitory Concentration 50, Ligands, Molecular Sequence Data, Mutagenesis, Mutation, Peptides, Prolactin, Prolactin-Releasing Hormone, Protein Binding, Receptors, G-Protein-Coupled, Sequence Homology, Amino Acid, Signal Transduction
Added January 24, 2015
1 Communities
1 Members
0 Resources
21 MeSH Terms
Maternal and cord blood hormone levels in the United States and China and the intrauterine origin of breast cancer.
Lagiou P, Samoli E, Okulicz W, Xu B, Lagiou A, Lipworth L, Georgila C, Vatten L, Adami HO, Trichopoulos D, Hsieh CC
(2011) Ann Oncol 22: 1102-1108
MeSH Terms: Adiponectin, Adult, Breast Neoplasms, China, Female, Fetal Blood, Gonadal Steroid Hormones, Hormones, Humans, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor Binding Proteins, Insulin-Like Growth Factor I, Pregnancy, Prolactin, Sex Hormone-Binding Globulin, Statistics, Nonparametric, United States, Young Adult
Added March 1, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Prevalence of valvular heart disease in a cohort of patients taking cabergoline for management of hyperprolactinemia.
Devin JK, Lakhani VT, Byrd BF, Blevins LS
(2008) Endocr Pract 14: 672-7
MeSH Terms: Adult, Cabergoline, Cohort Studies, Echocardiography, Ergolines, Female, Heart Valve Diseases, Humans, Hyperprolactinemia, Male, Middle Aged
Added December 10, 2013
0 Communities
1 Members
0 Resources
11 MeSH Terms
Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation.
Muraoka-Cook RS, Sandahl M, Hunter D, Miraglia L, Earp HS
(2008) Mol Endocrinol 22: 2307-21
MeSH Terms: Animals, Cell Differentiation, Cell Line, Enzyme Activation, Epithelial Cells, ErbB Receptors, Female, Gene Expression Regulation, Heparin-binding EGF-like Growth Factor, Intercellular Signaling Peptides and Proteins, Janus Kinase 2, Mammary Glands, Animal, Mice, Phosphorylation, Pregnancy, Prolactin, Receptor, ErbB-4, Receptors, Prolactin, STAT5 Transcription Factor, Signal Transduction, Tyrosine
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function.
Sun Y, Boyd K, Xu W, Ma J, Jackson CW, Fu A, Shillingford JM, Robinson GW, Hennighausen L, Hitzler JK, Ma Z, Morris SW
(2006) Mol Cell Biol 26: 5809-26
MeSH Terms: Animals, Animals, Newborn, Apoptosis, Child, Failure to Thrive, Female, Gene Expression Profiling, Gene Expression Regulation, Gene Targeting, Heart, Humans, Infant, Lactation, Leukemia, Megakaryoblastic, Acute, Male, Mammary Glands, Animal, Mice, Mice, Inbred C57BL, Mice, Knockout, Milk, Myocytes, Cardiac, Oligonucleotide Array Sequence Analysis, Oxytocin, Pregnancy, Prolactin, STAT3 Transcription Factor, Serum Response Factor, Trans-Activators
Added March 5, 2014
0 Communities
1 Members
0 Resources
28 MeSH Terms
Characterization of a naturally-occurring polymorphism in the UHR-1 gene encoding the putative rat prolactin-releasing peptide receptor.
Ellacott KL, Donald EL, Clarkson P, Morten J, Masters D, Brennand J, Luckman SM
(2005) Peptides 26: 675-81
MeSH Terms: Animals, Base Sequence, DNA Primers, Hypothalamic Hormones, Molecular Sequence Data, Neuropeptides, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Prolactin-Releasing Hormone, Rats, Rats, Sprague-Dawley, Receptors, G-Protein-Coupled, Receptors, Neuropeptide, Species Specificity
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms