Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 15

Publication Record

Connections

Prolylcarboxypeptidase independently activates plasma prekallikrein (fletcher factor).
Wang J, Matafonov A, Madkhali H, Mahdi F, Watson D, Schmaier AH, Gailani D, Shariat-Madar Z
(2014) Curr Mol Med 14: 1173-85
MeSH Terms: Amino Acid Sequence, Carboxypeptidases, Catalytic Domain, Cell Line, Enzyme Activation, Enzyme Assays, Humans, Kinetics, Molecular Sequence Data, Prekallikrein, Proteolysis, Substrate Specificity
Added January 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Influence of a novel inhibitor (UM8190) of prolylcarboxypeptidase (PRCP) on appetite and thrombosis.
Rabey FM, Gadepalli RS, Diano S, Cheng Q, Tabrizian T, Gailani D, Rimoldi JM, Shariat-Madar Z
(2012) Curr Med Chem 19: 4194-206
MeSH Terms: Animals, Appetite, Appetite Depressants, Bradykinin, Carboxypeptidases, Cell Line, Disease Models, Animal, Fibrinolytic Agents, Humans, Mice, Mice, Inbred C57BL, Nitric Oxide, Prekallikrein, Proline, Protease Inhibitors, Thrombosis
Added May 19, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding.
Revenko AS, Gao D, Crosby JR, Bhattacharjee G, Zhao C, May C, Gailani D, Monia BP, MacLeod AR
(2011) Blood 118: 5302-11
MeSH Terms: Animals, Disease Models, Animal, Factor XII, Factor XII Deficiency, Gene Knockdown Techniques, Hemorrhage, Hemostasis, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Oligonucleotides, Antisense, Prekallikrein, RNA, Messenger, Risk Factors, Thrombosis
Added May 19, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Structure and function of factor XI.
Emsley J, McEwan PA, Gailani D
(2010) Blood 115: 2569-77
MeSH Terms: Blood Coagulation, Blood Platelets, Catalytic Domain, Dimerization, Enzyme Activation, Evolution, Molecular, Factor IX, Factor XI, Factor XI Deficiency, Forecasting, Humans, Models, Molecular, Mutation, Platelet Membrane Glycoproteins, Prekallikrein, Protein Binding, Protein Conformation, Protein Interaction Mapping, Protein Structure, Tertiary, Structure-Activity Relationship
Added May 19, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Evolution of the contact phase of vertebrate blood coagulation.
Ponczek MB, Gailani D, Doolittle RF
(2008) J Thromb Haemost 6: 1876-83
MeSH Terms: Animals, Biological Evolution, Blood Coagulation, Computational Biology, Factor XII, Phylogeny, Prekallikrein, Vertebrates
Added May 19, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain.
Kravtsov DV, Wu W, Meijers JC, Sun MF, Blinder MA, Dang TP, Wang H, Gailani D
(2004) Blood 104: 128-34
MeSH Terms: Adult, Amino Acid Substitution, Animals, Catalytic Domain, Cell Line, Coleoptera, Dimerization, Factor XI, Factor XI Deficiency, Fibroblasts, Gene Expression, Genes, Dominant, Heterozygote, Humans, Intracellular Space, Luciferases, Male, Middle Aged, Pedigree, Prekallikrein, Recombinant Proteins, Transfection
Added May 19, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Factor XI apple domains and protein dimerization.
Cheng Q, Sun MF, Kravtsov DV, Aktimur A, Gailani D
(2003) J Thromb Haemost 1: 2340-7
MeSH Terms: Binding Sites, Chromatography, Gel, Cloning, Molecular, Dimerization, Disulfides, Electrophoresis, Polyacrylamide Gel, Factor IX, Humans, Prekallikrein, Protein Structure, Tertiary, Recombinant Fusion Proteins
Added May 19, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Fine mapping of the H-kininogen binding site in plasma prekallikrein apple domain 2.
Renné T, Sugiyama A, Gailani D, Jahnen-Dechent W, Walter U, Müller-Esterl W
(2002) Int Immunopharmacol 2: 1867-73
MeSH Terms: Antibodies, Monoclonal, Binding Sites, Blotting, Western, Electrophoresis, Polyacrylamide Gel, Epitope Mapping, Epitopes, Humans, Immunoassay, Kininogen, High-Molecular-Weight, Plasma Kallikrein, Prekallikrein, Recombinant Fusion Proteins, Sequence Deletion
Added May 19, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Molecular cloning and biochemical characterization of rabbit factor XI.
Sinha D, Marcinkiewicz M, Gailani D, Walsh PN
(2002) Biochem J 367: 49-56
MeSH Terms: Amino Acid Sequence, Animals, Chromatography, Cloning, Molecular, Cysteine, DNA, Complementary, Dimerization, Electrophoresis, Polyacrylamide Gel, Factor XI, Humans, Kinetics, Molecular Sequence Data, Prekallikrein, Rabbits, Reverse Transcriptase Polymerase Chain Reaction, Sequence Homology, Amino Acid, Time Factors
Added May 19, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Characterization of the H-kininogen-binding site on factor XI: a comparison of factor XI and plasma prekallikrein.
Renné T, Gailani D, Meijers JC, Müller-Esterl W
(2002) J Biol Chem 277: 4892-9
MeSH Terms: Alternative Splicing, Animals, Binding Sites, Blotting, Western, Cell Line, Cricetinae, Dose-Response Relationship, Drug, Electrophoresis, Polyacrylamide Gel, Enzyme-Linked Immunosorbent Assay, Factor XI, Humans, Inhibitory Concentration 50, Kininogen, High-Molecular-Weight, Precipitin Tests, Prekallikrein, Protein Binding, Protein Structure, Tertiary, Recombinant Fusion Proteins
Added May 19, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms