Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 10

Publication Record

Connections

Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.
Triplett TA, Cardenas KT, Lancaster JN, Hu Z, Selden HJ, Jasso GJ, Balasubramanyam S, Chan K, Li L, Chen X, Marcogliese AN, Davé UP, Love PE, Ehrlich LI
(2016) Proc Natl Acad Sci U S A 113: E1016-25
MeSH Terms: Animals, Cell Line, Tumor, Cell Survival, Dendritic Cells, Female, Humans, Male, Mice, Neoplasm Proteins, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Receptor, IGF Type 1, Receptor, Platelet-Derived Growth Factor beta, Receptors, Somatomedin, Signal Transduction, Tumor Microenvironment
Added February 22, 2016
0 Communities
1 Members
0 Resources
15 MeSH Terms
LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways.
Smith S, Tripathi R, Goodings C, Cleveland S, Mathias E, Hardaway JA, Elliott N, Yi Y, Chen X, Downing J, Mullighan C, Swing DA, Tessarollo L, Li L, Love P, Jenkins NA, Copeland NG, Thompson MA, Du Y, Davé UP
(2014) PLoS One 9: e85883
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Base Sequence, Basic Helix-Loop-Helix Transcription Factors, CD2 Antigens, Carcinogenesis, Cell Line, Tumor, E-Box Elements, Gene Expression Regulation, Leukemic, Homeodomain Proteins, Humans, LIM Domain Proteins, Leukemia, T-Cell, Mice, Mice, Transgenic, Molecular Sequence Data, Neoplasm Proteins, Oncogenes, Penetrance, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Promoter Regions, Genetic, Protein Binding, Proto-Oncogene Proteins, Signal Transduction, Transcription Factors, Transcription, Genetic, Up-Regulation
Added March 5, 2014
0 Communities
2 Members
0 Resources
27 MeSH Terms
Epigenetic regulation of the Ink4a-Arf (Cdkn2a) tumor suppressor locus in the initiation and progression of Notch1-driven T cell acute lymphoblastic leukemia.
Volanakis EJ, Boothby MR, Sherr CJ
(2013) Exp Hematol 41: 377-86
MeSH Terms: Animals, Binding Sites, Bone Marrow Cells, Cell Line, Cell Transformation, Neoplastic, Cells, Cultured, Coculture Techniques, Cyclin-Dependent Kinase Inhibitor p16, Disease Progression, Dogs, Epigenesis, Genetic, Flow Cytometry, Gene Expression, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Mutation, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Receptor, Notch1, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, T-Lymphocytes, Thymocytes, Tumor Suppressor Protein p14ARF
Added December 10, 2013
0 Communities
2 Members
0 Resources
25 MeSH Terms
Targeting nonclassical oncogenes for therapy in T-ALL.
Subramaniam PS, Whye DW, Efimenko E, Chen J, Tosello V, De Keersmaecker K, Kashishian A, Thompson MA, Castillo M, Cordon-Cardo C, Davé UP, Ferrando A, Lannutti BJ, Diacovo TG
(2012) Cancer Cell 21: 459-72
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Binding Sites, Cell Line, Tumor, Cell Proliferation, Cell Transformation, Neoplastic, Class I Phosphatidylinositol 3-Kinases, Class Ib Phosphatidylinositol 3-Kinase, Drug Design, Gene Silencing, Humans, Mice, PTEN Phosphohydrolase, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Protein Isoforms, Purines, Quinazolinones
Added March 5, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia.
Lee K, Nam KT, Cho SH, Gudapati P, Hwang Y, Park DS, Potter R, Chen J, Volanakis E, Boothby M
(2012) J Exp Med 209: 713-28
MeSH Terms: Active Transport, Cell Nucleus, Animals, Carrier Proteins, Cell Differentiation, Cell Lineage, Forkhead Box Protein O1, Forkhead Transcription Factors, Mice, Mice, Inbred C57BL, NF-kappa B, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-akt, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, Rapamycin-Insensitive Companion of mTOR Protein, Receptors, Notch, TOR Serine-Threonine Kinases, Thymocytes
Added December 10, 2013
2 Communities
3 Members
0 Resources
18 MeSH Terms
Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.
Chmielecki J, Peifer M, Viale A, Hutchinson K, Giltnane J, Socci ND, Hollis CJ, Dean RS, Yenamandra A, Jagasia M, Kim AS, Davé UP, Thomas RK, Pao W
(2012) Genes Chromosomes Cancer 51: 54-65
MeSH Terms: Adult, Algorithms, Amino Acid Sequence, Base Sequence, Cell Line, Tumor, Computational Biology, Cytoskeletal Proteins, Gene Order, HEK293 Cells, Humans, K562 Cells, Karyotyping, Male, Molecular Sequence Data, Myeloproliferative Disorders, Oncogene Proteins, Fusion, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Protein-Tyrosine Kinases, Sequence Alignment, Sequence Analysis, DNA, Translocation, Genetic
Added September 3, 2013
0 Communities
4 Members
0 Resources
21 MeSH Terms
Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.
Treanor LM, Volanakis EJ, Zhou S, Lu T, Sherr CJ, Sorrentino BP
(2011) Blood 117: 5453-62
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Cell Transformation, Neoplastic, Cocarcinogenesis, Cyclin-Dependent Kinase Inhibitor p16, DNA-Binding Proteins, Disease Progression, Female, Gene Expression, LIM Domain Proteins, Loss of Heterozygosity, Male, Metalloproteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Mutation, Neoplastic Stem Cells, Precursor Cells, T-Lymphoid, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Promoter Regions, Genetic, Receptor, Notch1, Signal Transduction
Added May 27, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Genetic variations in GRIA1 on chromosome 5q33 related to asparaginase hypersensitivity.
Chen SH, Pei D, Yang W, Cheng C, Jeha S, Cox NJ, Evans WE, Pui CH, Relling MV
(2010) Clin Pharmacol Ther 88: 191-6
MeSH Terms: Adolescent, Alleles, Antineoplastic Agents, Asparaginase, Child, Preschool, Chromosomes, Human, Pair 5, Cohort Studies, DNA, Drug Hypersensitivity, Female, Genetic Predisposition to Disease, Genetic Variation, Genome-Wide Association Study, Genotype, Humans, Male, Micronucleus, Germline, Polymorphism, Single Nucleotide, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Receptors, AMPA, Reproducibility of Results, Risk
Added February 22, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
Developmental strategies for evasion of Arf tumor suppression.
Volanakis EJ, Sherr CJ
(2010) Cell Cycle 9: 14-5
MeSH Terms: Animals, CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Cyclin-Dependent Kinase Inhibitor p16, Epigenesis, Genetic, Hematopoietic Stem Cells, Humans, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Receptor, Notch1
Added May 27, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Stage-specific Arf tumor suppression in Notch1-induced T-cell acute lymphoblastic leukemia.
Volanakis EJ, Williams RT, Sherr CJ
(2009) Blood 114: 4451-9
MeSH Terms: Adoptive Transfer, Animals, Blotting, Southern, Blotting, Western, Cell Differentiation, Cyclin-Dependent Kinase Inhibitor p16, Disease Models, Animal, Humans, Mice, Mice, Knockout, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Receptor, Notch1, Reverse Transcriptase Polymerase Chain Reaction, T-Lymphocytes, Transduction, Genetic, Transfection
Added May 27, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms