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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 13

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Sequence context modulation of polycyclic aromatic hydrocarbon-induced mutagenesis.
Chary P, Stone MP, Lloyd RS
(2013) Environ Mol Mutagen 54: 652-8
MeSH Terms: Base Pair Mismatch, DNA Adducts, DNA Polymerase I, DNA-Directed DNA Polymerase, Escherichia coli, Molecular Structure, Mutagenesis, Mutagens, Polycyclic Aromatic Hydrocarbons, Stereoisomerism
Added March 7, 2014
0 Communities
1 Members
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10 MeSH Terms
Polycyclic aromatic hydrocarbons: determinants of urinary 1-hydroxypyrene glucuronide concentration and risk of colorectal cancer in the Shanghai Women's Health Study.
Hofmann JN, Liao LM, Strickland PT, Shu XO, Yang G, Ji BT, Li HL, Rothman N, Kamangar F, Gao YT, Zheng W, Chow WH
(2013) BMC Cancer 13: 282
MeSH Terms: Case-Control Studies, Chromatography, Affinity, Colorectal Neoplasms, Female, Glucuronates, Humans, Middle Aged, Polycyclic Aromatic Hydrocarbons, Pyrenes, Risk Factors
Added May 4, 2017
0 Communities
1 Members
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10 MeSH Terms
Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6.
Shimada T, Murayama N, Yamazaki H, Tanaka K, Takenaka S, Komori M, Kim D, Guengerich FP
(2013) Chem Res Toxicol 26: 529-37
MeSH Terms: Amines, Aryl Hydrocarbon Hydroxylases, Biotransformation, Carcinogens, Cytochrome P-450 CYP1B1, Cytochrome P-450 CYP2A6, Environmental Pollutants, Escherichia coli, Genes, Bacterial, Heterocyclic Compounds, Humans, Molecular Docking Simulation, Polycyclic Aromatic Hydrocarbons, Salmonella typhimurium
Added March 7, 2014
0 Communities
1 Members
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14 MeSH Terms
Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.
Shimada T, Kim D, Murayama N, Tanaka K, Takenaka S, Nagy LD, Folkman LM, Foroozesh MK, Komori M, Yamazaki H, Guengerich FP
(2013) Chem Res Toxicol 26: 517-28
MeSH Terms: Aryl Hydrocarbon Hydroxylases, Binding Sites, Carcinogens, Cytochrome P-450 CYP1B1, Cytochrome P-450 CYP2A6, Environmental Pollutants, Escherichia coli, Flavonoids, Humans, Molecular Docking Simulation, Polycyclic Aromatic Hydrocarbons
Added March 7, 2014
0 Communities
1 Members
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11 MeSH Terms
Breast cancer and urinary biomarkers of polycyclic aromatic hydrocarbon and oxidative stress in the Shanghai Women's Health Study.
Lee KH, Shu XO, Gao YT, Ji BT, Yang G, Blair A, Rothman N, Zheng W, Chow WH, Kang D
(2010) Cancer Epidemiol Biomarkers Prev 19: 877-83
MeSH Terms: Biomarkers, Tumor, Breast Neoplasms, Case-Control Studies, China, Female, Humans, Middle Aged, Oxidative Stress, Polycyclic Aromatic Hydrocarbons, Risk Factors
Added May 4, 2017
0 Communities
1 Members
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10 MeSH Terms
Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic activity.
Shimada T, Murajama N, Tanaka K, Takenaka S, Imai Y, Hopkins NE, Foroozesh MK, Alworth WL, Yamazaki H, Guengerich FP, Komori M
(2008) Chem Res Toxicol 21: 2313-23
MeSH Terms: Aryl Hydrocarbon Hydroxylases, Computer Simulation, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1B1, Enzyme Inhibitors, Humans, Models, Molecular, Polycyclic Aromatic Hydrocarbons, Protein Conformation
Added March 26, 2014
0 Communities
1 Members
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9 MeSH Terms
Different mechanisms for inhibition of human cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic inhibitors.
Shimada T, Murayama N, Okada K, Funae Y, Yamazaki H, Guengerich FP
(2007) Chem Res Toxicol 20: 489-96
MeSH Terms: Aryl Hydrocarbon Hydroxylases, Catalysis, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1A2, Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP1B1, Enzyme Inhibitors, Humans, Kinetics, Oxazines, Polycyclic Aromatic Hydrocarbons
Added March 5, 2014
0 Communities
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11 MeSH Terms
Translesion synthesis across polycyclic aromatic hydrocarbon diol epoxide adducts of deoxyadenosine by Sulfolobus solfataricus DNA polymerase Dpo4.
Zang H, Chowdhury G, Angel KC, Harris TM, Guengerich FP
(2006) Chem Res Toxicol 19: 859-67
MeSH Terms: DNA-Directed DNA Polymerase, Deoxyadenosines, Deoxyribonucleotides, Epoxy Compounds, Gas Chromatography-Mass Spectrometry, Kinetics, Molecular Structure, Oligonucleotides, Polycyclic Aromatic Hydrocarbons, Sulfolobus solfataricus, Temperature
Added March 5, 2014
0 Communities
1 Members
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11 MeSH Terms
Inhibition of human cytochrome P450 1A1-, 1A2-, and 1B1-mediated activation of procarcinogens to genotoxic metabolites by polycyclic aromatic hydrocarbons.
Shimada T, Guengerich FP
(2006) Chem Res Toxicol 19: 288-94
MeSH Terms: Aryl Hydrocarbon Hydroxylases, Carcinogens, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1A2, Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP1B1, Enzyme Activation, Enzyme Inhibitors, Humans, Molecular Structure, Polycyclic Aromatic Hydrocarbons, Salmonella typhimurium, Structure-Activity Relationship
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Kinetics of nucleotide incorporation opposite polycyclic aromatic hydrocarbon-DNA adducts by processive bacteriophage T7 DNA polymerase.
Zang H, Harris TM, Guengerich FP
(2005) Chem Res Toxicol 18: 389-400
MeSH Terms: Bacteriophage T7, Catalysis, DNA, DNA Adducts, DNA-Directed DNA Polymerase, HIV Reverse Transcriptase, HIV-1, Kinetics, Molecular Conformation, Oligonucleotides, Polycyclic Aromatic Hydrocarbons
Added March 5, 2014
0 Communities
1 Members
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11 MeSH Terms