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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 20

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Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway.
Gobert AP, Latour YL, Asim M, Finley JL, Verriere TG, Barry DP, Milne GL, Luis PB, Schneider C, Rivera ES, Lindsey-Rose K, Schey KL, Delgado AG, Sierra JC, Piazuelo MB, Wilson KT
(2019) mBio 10:
MeSH Terms: Animals, Bacteria, Gene Silencing, Helicobacter pylori, Histones, Humans, Immune Evasion, Immunity, Innate, Immunoglobulins, Macrophages, Male, Metabolic Networks and Pathways, Mice, Mice, Inbred C57BL, Nitric Oxide Synthase Type II, Phosphatidylinositol 3-Kinases, Polyamines, RAW 264.7 Cells, Spermidine, Spermine, Sulfur, Transcription Factors
Added November 1, 2019
0 Communities
2 Members
0 Resources
22 MeSH Terms
The role of polyamines in the regulation of macrophage polarization and function.
Latour YL, Gobert AP, Wilson KT
(2020) Amino Acids 52: 151-160
MeSH Terms: Animals, Cell Polarity, Humans, Macrophage Activation, Macrophages, Polyamines, Transcription, Genetic
Added August 6, 2020
0 Communities
1 Members
0 Resources
7 MeSH Terms
Polyamine- and NADPH-dependent generation of ROS during Helicobacter pylori infection: A blessing in disguise.
Gobert AP, Wilson KT
(2017) Free Radic Biol Med 105: 16-27
MeSH Terms: Animals, DNA Damage, Helicobacter Infections, Helicobacter pylori, Host-Pathogen Interactions, Humans, NADP, NADPH Oxidases, Oxidative Stress, Polyamines, Reactive Oxygen Species
Added October 2, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
Arginase 2 deletion leads to enhanced M1 macrophage activation and upregulated polyamine metabolism in response to Helicobacter pylori infection.
Hardbower DM, Asim M, Murray-Stewart T, Casero RA, Verriere T, Lewis ND, Chaturvedi R, Piazuelo MB, Wilson KT
(2016) Amino Acids 48: 2375-88
MeSH Terms: Animals, Arginase, Biogenic Polyamines, Helicobacter Infections, Helicobacter pylori, Immune Evasion, Macrophage Activation, Macrophages, Mice, Mice, Knockout, Nitric Oxide Synthase Type II, Stomach, Th1 Cells, Th17 Cells
Added April 22, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Cytotoxicity of 1,4-diamino-2-butanone, a putrescine analogue, to RKO cells: mechanism and redox imbalance.
Soares CO, Boiani M, Marnett LJ, Bechara EJ
(2013) Free Radic Res 47: 672-82
MeSH Terms: Apoptosis, Cell Line, Tumor, Cell Survival, Glutathione, Humans, Hydrogen Peroxide, Metabolic Networks and Pathways, Oxidation-Reduction, Polyamines, Putrescine, Reactive Oxygen Species, Superoxides
Added June 1, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Editorial: Orchestration of macrophage polarization by polyamines.
Gobert AP, Wilson KT
(2012) J Leukoc Biol 91: 677-9
MeSH Terms: Animals, Arginase, Cytokines, Inflammation Mediators, Interleukin-4, Lipopolysaccharides, Macrophages, Polyamines
Added March 5, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Arginine and polyamines in Helicobacter pylori-induced immune dysregulation and gastric carcinogenesis.
Chaturvedi R, de Sablet T, Coburn LA, Gobert AP, Wilson KT
(2012) Amino Acids 42: 627-40
MeSH Terms: Arginine, Biogenic Polyamines, Cell Transformation, Neoplastic, DNA Damage, Humans, Nitric Oxide, Nitric Oxide Synthase Type II, Oxidative Stress, Stomach Neoplasms
Added March 5, 2014
0 Communities
3 Members
0 Resources
9 MeSH Terms
Methods to evaluate alterations in polyamine metabolism caused by Helicobacter pylori infection.
Gobert AP, Chaturvedi R, Wilson KT
(2011) Methods Mol Biol 720: 409-25
MeSH Terms: Acetyltransferases, Animals, Apoptosis, Arginase, Arsenicals, Biochemistry, Cells, Cultured, Enzyme Assays, Helicobacter Infections, Helicobacter pylori, Humans, Immunoblotting, Luciferases, Macrophages, Mice, Nitrogen Dioxide, Ornithine Decarboxylase, Oxidoreductases Acting on CH-NH Group Donors, Polyamines, Promoter Regions, Genetic, RNA, Messenger, Transfection
Added March 5, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production.
Chaturvedi R, Asim M, Hoge S, Lewis ND, Singh K, Barry DP, de Sablet T, Piazuelo MB, Sarvaria AR, Cheng Y, Closs EI, Casero RA, Gobert AP, Wilson KT
(2010) Gastroenterology 139: 1686-98, 1698.e1-6
MeSH Terms: Animals, Arginine, Cationic Amino Acid Transporter 2, Cells, Cultured, Disease Models, Animal, Gastric Mucosa, Gastritis, Gene Expression Regulation, Helicobacter Infections, Helicobacter pylori, Humans, Immunity, Cellular, Macrophages, Mice, Mice, Inbred C57BL, Nitric Oxide, Nitric Oxide Synthase Type II, Ornithine Decarboxylase, Polyamines, RNA, Reverse Transcriptase Polymerase Chain Reaction, Spermine
Added March 5, 2014
0 Communities
3 Members
0 Resources
22 MeSH Terms
Polyamine-dependent activation of Rac1 is stimulated by focal adhesion-mediated Tiam1 activation.
Elias BC, Bhattacharya S, Ray RM, Johnson LR
(2010) Cell Adh Migr 4: 419-30
MeSH Terms: Cell Adhesion, Cell Line, Cell Movement, Enzyme Activation, Extracellular Matrix, Fibronectins, Focal Adhesion Protein-Tyrosine Kinases, Focal Adhesions, Guanine Nucleotide Exchange Factors, Models, Biological, Oligopeptides, Polyamines, Protein Binding, Signal Transduction, rac1 GTP-Binding Protein, src-Family Kinases
Added February 25, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms