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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 57

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A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin.
Kondo J, Huh WJ, Franklin JL, Heinrich MC, Rubin BP, Coffey RJ
(2020) J Pathol 252: 441-450
MeSH Terms: Animals, Biomarkers, Tumor, Disease Models, Animal, Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumors, Mice, Muscle, Smooth, Mutation, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-kit, Receptor, Platelet-Derived Growth Factor alpha
Added September 25, 2020
1 Communities
0 Members
0 Resources
11 MeSH Terms
The Pan-Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA.
Disel U, Madison R, Abhishek K, Chung JH, Trabucco SE, Matos AO, Frampton GM, Albacker LA, Reddy V, Karadurmus N, Benson A, Webster J, Paydas S, Cabanillas R, Nangia C, Ozturk MA, Millis SZ, Pal SK, Wilky B, Sokol ES, Gay LM, Soman S, Ganesan S, Janeway K, Stephens PJ, Zhu VW, Ou SI, Lovly CM, Gounder M, Schrock AB, Ross JS, Miller VA, Klempner SJ, Ali SM
(2020) Oncologist 25: e39-e47
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Gene Amplification, Humans, Middle Aged, Neoplasms, Receptor Protein-Tyrosine Kinases, Receptor, Platelet-Derived Growth Factor alpha, Vascular Endothelial Growth Factor Receptor-2, Young Adult
Added September 10, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
Probing the Virtual Proteome to Identify Novel Disease Biomarkers.
Mosley JD, Benson MD, Smith JG, Melander O, Ngo D, Shaffer CM, Ferguson JF, Herzig MS, McCarty CA, Chute CG, Jarvik GP, Gordon AS, Palmer MR, Crosslin DR, Larson EB, Carrell DS, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Kitchner TE, Linneman JG, Namjou B, Williams MS, Ritchie MD, Borthwick KM, Kiryluk K, Mentch FD, Sleiman PM, Karlson EW, Verma SS, Zhu Y, Vasan RS, Yang Q, Denny JC, Roden DM, Gerszten RE, Wang TJ
(2018) Circulation 138: 2469-2481
MeSH Terms: Adult, Aged, Aged, 80 and over, Biomarkers, Carotid Artery Diseases, Female, Genome-Wide Association Study, Genotype, Humans, Lectins, C-Type, Male, Middle Aged, Odds Ratio, Phenotype, Polymorphism, Single Nucleotide, Proteome, Proteomics, Receptor, Platelet-Derived Growth Factor beta
Added April 2, 2019
0 Communities
2 Members
0 Resources
18 MeSH Terms
Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin.
Erdogan B, Ao M, White LM, Means AL, Brewer BM, Yang L, Washington MK, Shi C, Franco OE, Weaver AM, Hayward SW, Li D, Webb DJ
(2017) J Cell Biol 216: 3799-3816
MeSH Terms: Cancer-Associated Fibroblasts, Cell Communication, Cell Line, Tumor, Cell Movement, Coculture Techniques, Extracellular Matrix, Fibronectins, Humans, Integrin alpha5beta1, Male, Mechanotransduction, Cellular, Neoplasm Invasiveness, Nonmuscle Myosin Type IIA, Prostatic Neoplasms, RNA Interference, Receptor, Platelet-Derived Growth Factor alpha, Time Factors, Transfection, Tumor Cells, Cultured, Tumor Microenvironment
Added March 14, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Development of a reliable automated screening system to identify small molecules and biologics that promote human β-cell regeneration.
Aamodt KI, Aramandla R, Brown JJ, Fiaschi-Taesch N, Wang P, Stewart AF, Brissova M, Powers AC
(2016) Am J Physiol Endocrinol Metab 311: E859-E868
MeSH Terms: Activins, Adenosine, Adenosine A2 Receptor Agonists, Adenosine-5'-(N-ethylcarboxamide), Adult, Automation, Cell Culture Techniques, Cell Proliferation, Drug Evaluation, Preclinical, Erythropoietin, Exenatide, Female, GABA Agents, Harmine, Humans, Incretins, Insulin-Secreting Cells, Male, Middle Aged, Monoamine Oxidase Inhibitors, Myostatin, Nucleosides, Peptides, Platelet-Derived Growth Factor, Prolactin, Regeneration, Serotonin, Serotonin Receptor Agonists, Vasodilator Agents, Venoms, Young Adult, gamma-Aminobutyric Acid
Added April 26, 2017
0 Communities
2 Members
0 Resources
32 MeSH Terms
Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation.
Triplett TA, Cardenas KT, Lancaster JN, Hu Z, Selden HJ, Jasso GJ, Balasubramanyam S, Chan K, Li L, Chen X, Marcogliese AN, Davé UP, Love PE, Ehrlich LI
(2016) Proc Natl Acad Sci U S A 113: E1016-25
MeSH Terms: Animals, Cell Line, Tumor, Cell Survival, Dendritic Cells, Female, Humans, Male, Mice, Neoplasm Proteins, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Receptor, IGF Type 1, Receptor, Platelet-Derived Growth Factor beta, Receptors, Somatomedin, Signal Transduction, Tumor Microenvironment
Added February 22, 2016
0 Communities
1 Members
0 Resources
15 MeSH Terms
Renal fibrosis is not reduced by blocking transforming growth factor-β signaling in matrix-producing interstitial cells.
Neelisetty S, Alford C, Reynolds K, Woodbury L, Nlandu-Khodo S, Yang H, Fogo AB, Hao CM, Harris RC, Zent R, Gewin L
(2015) Kidney Int 88: 503-14
MeSH Terms: Actins, Animals, Aristolochic Acids, Cells, Cultured, Collagen Type I, Disease Models, Animal, Extracellular Matrix, Fibrosis, Kidney, Kidney Diseases, Mice, Inbred C57BL, Mice, Knockout, Protein-Serine-Threonine Kinases, Receptor, Platelet-Derived Growth Factor beta, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Time Factors, Transforming Growth Factor beta, Ureteral Obstruction
Added August 3, 2015
1 Communities
3 Members
0 Resources
20 MeSH Terms
Stretching fibroblasts remodels fibronectin and alters cancer cell migration.
Ao M, Brewer BM, Yang L, Franco Coronel OE, Hayward SW, Webb DJ, Li D
(2015) Sci Rep 5: 8334
MeSH Terms: Cell Movement, Fibroblasts, Fibronectins, Humans, Male, Neoplasm Proteins, Prostatic Neoplasms, Receptor, Platelet-Derived Growth Factor beta, Signal Transduction, Tumor Cells, Cultured
Added February 19, 2015
0 Communities
2 Members
0 Resources
10 MeSH Terms
PDGFRB-rearranged T-lymphoblastic leukemia/lymphoma occurring with myeloid neoplasms: the missing link supporting a stem cell origin.
Ondrejka SL, Jegalian AG, Kim AS, Chabot-Richards DS, Giltnane J, Czuchlewski DR, Shetty S, Sekeres MA, Yenamandra A, Head D, Jagasia M, Hsi ED
(2014) Haematologica 99: e148-51
MeSH Terms: Adult, Bone Marrow, Gene Expression, Humans, Karyotype, Leukemia, Myeloid, Male, Middle Aged, Neoplastic Stem Cells, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Receptor, Platelet-Derived Growth Factor beta, Translocation, Genetic
Added January 20, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions.
Lovly CM, Gupta A, Lipson D, Otto G, Brennan T, Chung CT, Borinstein SC, Ross JS, Stephens PJ, Miller VA, Coffin CM
(2014) Cancer Discov 4: 889-95
MeSH Terms: Anaplastic Lymphoma Kinase, Biomarkers, Tumor, Child, Crizotinib, Humans, Inflammation, Male, Neoplasms, Muscle Tissue, Oncogene Proteins, Fusion, Protein-Tyrosine Kinases, Proto-Oncogene Proteins, Pyrazoles, Pyridines, Receptor Protein-Tyrosine Kinases, Receptor, Platelet-Derived Growth Factor beta
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms