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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 38

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Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib.
Latifi Y, Moccetti F, Wu M, Xie A, Packwood W, Qi Y, Ozawa K, Shentu W, Brown E, Shirai T, McCarty OJ, Ruggeri Z, Moslehi J, Chen J, Druker BJ, López JA, Lindner JR
(2019) Blood 133: 1597-1606
MeSH Terms: Animals, Aorta, Cardiovascular Diseases, Endothelium, Fusion Proteins, bcr-abl, Humans, Imidazoles, Ischemia, Mice, Mice, Knockout, Platelet Adhesiveness, Protein Kinase Inhibitors, Pyridazines, Thrombotic Microangiopathies, Ventricular Dysfunction, von Willebrand Factor
Added February 24, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
Heparin-functionalized polymer graft surface eluting MK2 inhibitory peptide to improve hemocompatibility and anti-neointimal activity.
Lee Y, Le Thi P, Seon GM, Ryu SB, Brophy CM, Kim Y, Park JC, Park KD, Cheung-Flynn J, Sung HJ
(2017) J Control Release 266: 321-330
MeSH Terms: Animals, Anticoagulants, Cell Movement, Cell Proliferation, Heparin, Humans, Myocytes, Smooth Muscle, Neointima, Peptides, Platelet Adhesiveness, Polyesters, Rats, Sprague-Dawley, Saphenous Vein, Thrombosis
Added May 22, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties.
Khanicheh E, Qi Y, Xie A, Mitterhuber M, Xu L, Mochizuki M, Daali Y, Jaquet V, Krause KH, Ruggeri ZM, Kuster GM, Lindner JR, Kaufmann BA
(2013) Arterioscler Thromb Vasc Biol 33: 2187-92
MeSH Terms: APOBEC-1 Deaminase, Acetophenones, Animals, Anti-Inflammatory Agents, Antioxidants, Aortic Diseases, Atherosclerosis, Biomarkers, Blotting, Western, Contrast Media, Cytidine Deaminase, Disease Models, Animal, Endothelium, Vascular, Enzyme Inhibitors, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Microbubbles, Molecular Imaging, NADPH Oxidases, Oxidative Stress, Phenotype, Platelet Adhesiveness, Platelet Glycoprotein GPIb-IX Complex, Receptors, LDL, Superoxides, Time Factors, Ultrasonography, Interventional, Vascular Cell Adhesion Molecule-1
Added August 29, 2013
1 Communities
0 Members
0 Resources
31 MeSH Terms
12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity.
Yeung J, Apopa PL, Vesci J, Stolla M, Rai G, Simeonov A, Jadhav A, Fernandez-Perez P, Maloney DJ, Boutaud O, Holman TR, Holinstat M
(2013) Thromb Haemost 110: 569-81
MeSH Terms: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid, Animals, Arachidonate 12-Lipoxygenase, Blood Platelets, Cyclooxygenase 1, Eicosanoids, Flow Cytometry, Humans, Mice, Mice, Transgenic, Platelet Activation, Platelet Adhesiveness, Platelet Aggregation, Platelet Membrane Glycoproteins, Receptors, Thrombin, Thrombosis, Time Factors
Added March 27, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
A murine model to characterize the antithrombotic effect of molecules targeting human von Willebrand factor.
Navarrete AM, Casari C, Legendre P, Marx I, Hu JR, Lenting PJ, Christophe OD, Denis CV
(2012) Blood 120: 2723-32
MeSH Terms: ADAMTS13 Protein, Animals, Antibodies, Monoclonal, Chlorides, Collagen, Disease Models, Animal, Enzyme-Linked Immunosorbent Assay, Ferric Compounds, Fibrinolytic Agents, Hemorrhage, Humans, Metalloendopeptidases, Mice, Mice, Inbred C57BL, Mice, Knockout, Mutagenesis, Site-Directed, Mutation, Platelet Adhesiveness, Platelet Glycoprotein GPIIb-IIIa Complex, Thrombosis, von Willebrand Factor
Added April 6, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Hemocompatibility of silicon-based substrates for biomedical implant applications.
Muthusubramaniam L, Lowe R, Fissell WH, Li L, Marchant RE, Desai TA, Roy S
(2011) Ann Biomed Eng 39: 1296-305
MeSH Terms: Biocompatible Materials, Biomedical Engineering, Blood Coagulation, Complement Activation, Humans, In Vitro Techniques, Materials Testing, Miniaturization, Platelet Activation, Platelet Adhesiveness, Polytetrafluoroethylene, Prostheses and Implants, Renal Replacement Therapy, Silicon, Stainless Steel, Surface Properties
Added August 21, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Suboptimal activation of protease-activated receptors enhances alpha2beta1 integrin-mediated platelet adhesion to collagen.
Marjoram RJ, Voss B, Pan Y, Dickeson SK, Zutter MM, Hamm HE, Santoro SA
(2009) J Biol Chem 284: 34640-7
MeSH Terms: Amino Acid Motifs, Animals, Blood Platelets, Carrier Proteins, Collagen, GTP-Binding Protein alpha Subunits, Gi-Go, Humans, Integrin alpha2beta1, Mice, Mice, Inbred C57BL, Peptides, Platelet Adhesiveness, Platelet Aggregation, Platelet Membrane Glycoproteins, Rats, Receptor, PAR-1, Receptors, Collagen, Receptors, G-Protein-Coupled, Receptors, IgG, Receptors, Thrombin, Signal Transduction, Thrombin, Type C Phospholipases
Added December 10, 2013
1 Communities
2 Members
0 Resources
23 MeSH Terms
Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2).
White-Adams TC, Berny MA, Tucker EI, Gertz JM, Gailani D, Urbanus RT, de Groot PG, Gruber A, McCarty OJ
(2009) Arterioscler Thromb Vasc Biol 29: 1602-7
MeSH Terms: Animals, Blood Platelets, Calcium, Factor XI, Humans, Kininogen, High-Molecular-Weight, LDL-Receptor Related Proteins, Ligands, Mice, Mice, Inbred C57BL, Platelet Adhesiveness, Receptors, Lipoprotein, Zinc
Added May 19, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Rap1b is critical for glycoprotein VI-mediated but not ADP receptor-mediated alpha2beta1 activation.
Wang Z, Holly SP, Larson MK, Liu J, Yuan W, Chrzanowska-Wodnicka M, White GC, Parise LV
(2009) J Thromb Haemost 7: 693-700
MeSH Terms: Animals, Blood Platelets, Cell Shape, Collagen, Integrin alpha2beta1, Mice, Mice, Knockout, Platelet Adhesiveness, Platelet Membrane Glycoproteins, Receptors, Purinergic P2, Signal Transduction, rap GTP-Binding Proteins
Added April 7, 2010
0 Communities
1 Members
0 Resources
12 MeSH Terms
Adherent platelets recruit and induce differentiation of murine embryonic endothelial progenitor cells to mature endothelial cells in vitro.
Langer H, May AE, Daub K, Heinzmann U, Lang P, Schumm M, Vestweber D, Massberg S, Schönberger T, Pfisterer I, Hatzopoulos AK, Gawaz M
(2006) Circ Res 98: e2-10
MeSH Terms: Animals, Blood Platelets, CD3 Complex, Cell Differentiation, Cell Movement, Cells, Cultured, Chemotaxis, Embryo, Mammalian, Endothelial Cells, Humans, Mice, Platelet Adhesiveness, Stem Cells
Added November 18, 2010
1 Communities
1 Members
0 Resources
13 MeSH Terms