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A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development.
Juber BA, Elgin TG, Fricke EM, Gong H, Reese J, McElroy SJ
(2020) J Vis Exp :
MeSH Terms: Acute Disease, Animals, Chorioamnionitis, Cytokines, Disease Models, Animal, Female, Fetus, Humans, Infant, Newborn, Intestines, Mice, Mothers, Paneth Cells, Placenta, Pregnancy, Prenatal Exposure Delayed Effects
Added January 7, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Palmitate induces apoptotic cell death and inflammasome activation in human placental macrophages.
Rogers LM, Serezani CH, Eastman AJ, Hasty AH, Englund-Ögge L, Jacobsson B, Vickers KC, Aronoff DM
(2020) Placenta 90: 45-51
MeSH Terms: Adult, Apoptosis, Cytokines, Female, Glucose, Humans, Inflammasomes, Insulin, Macrophages, Palmitic Acid, Placenta, Pregnancy
Added March 3, 2020
0 Communities
2 Members
0 Resources
12 MeSH Terms
The Impact of Natural Selection on the Evolution and Function of Placentally Expressed Galectins.
Ely ZA, Moon JM, Sliwoski GR, Sangha AK, Shen XX, Labella AL, Meiler J, Capra JA, Rokas A
(2019) Genome Biol Evol 11: 2574-2592
MeSH Terms: Animals, Biological Evolution, Eutheria, Evolution, Molecular, Female, Galectins, Haplotypes, Humans, Models, Molecular, Phylogeny, Placenta, Polymorphism, Single Nucleotide, Pregnancy, Selection, Genetic
Added March 3, 2020
0 Communities
2 Members
0 Resources
14 MeSH Terms
Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP.
Byndloss MX, Tsai AY, Walker GT, Miller CN, Young BM, English BC, Seyffert N, Kerrinnes T, de Jong MF, Atluri VL, Winter MG, Celli J, Tsolis RM
(2019) mBio 10:
MeSH Terms: Animals, Brucella abortus, Cell Death, Endoplasmic Reticulum Stress, Female, Mice, Mice, Inbred C57BL, Nod1 Signaling Adaptor Protein, Nod2 Signaling Adaptor Protein, Placenta, Pregnancy, Transcription Factor CHOP, Trophoblasts, Type IV Secretion Systems, Unfolded Protein Response
Added March 30, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Sex modifies placental gene expression in response to metabolic and inflammatory stress.
Barke TL, Money KM, Du L, Serezani A, Gannon M, Mirnics K, Aronoff DM
(2019) Placenta 78: 1-9
MeSH Terms: Animals, Diabetes, Gestational, Diet, High-Fat, Female, Fetal Development, Fetus, Gene Expression, Inflammation, Male, Mice, Mice, Inbred C57BL, Obesity, Placenta, Pregnancy, Pregnancy Complications, Sex Characteristics, Stress, Physiological, Transcriptome
Added April 15, 2019
0 Communities
1 Members
0 Resources
18 MeSH Terms
Genome-wide maps of distal gene regulatory enhancers active in the human placenta.
Zhang J, Simonti CN, Capra JA
(2018) PLoS One 13: e0209611
MeSH Terms: Chromosome Mapping, Computational Biology, Enhancer Elements, Genetic, Female, Genes, Regulator, Genome-Wide Association Study, Genomics, Humans, Machine Learning, Molecular Sequence Annotation, Placenta, Pregnancy, ROC Curve
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Bacterial DNA is present in the fetal intestine and overlaps with that in the placenta in mice.
Martinez KA, Romano-Keeler J, Zackular JP, Moore DJ, Brucker RM, Hooper C, Meng S, Brown N, Mallal S, Reese J, Aronoff DM, Shin H, Dominguez-Bello MG, Weitkamp JH
(2018) PLoS One 13: e0197439
MeSH Terms: Amniotic Fluid, Animals, DNA, Bacterial, Female, Intestinal Mucosa, Intestines, Mice, Placenta, Pregnancy, RNA, Ribosomal, 16S, Vagina
Added May 18, 2018
0 Communities
3 Members
0 Resources
11 MeSH Terms
Lipopolysaccharide-induced maternal inflammation induces direct placental injury without alteration in placental blood flow and induces a secondary fetal intestinal injury that persists into adulthood.
Fricke EM, Elgin TG, Gong H, Reese J, Gibson-Corley KN, Weiss RM, Zimmerman K, Bowdler NC, Kalantera KM, Mills DA, Underwood MA, McElroy SJ
(2018) Am J Reprod Immunol 79: e12816
MeSH Terms: Amniotic Fluid, Animals, Digestive System Diseases, Disease Models, Animal, Female, Fetal Diseases, Inflammation, Interleukins, Lipopolysaccharides, Mice, Mice, Inbred C57BL, Necrosis, Placenta, Placental Insufficiency, Pregnancy, Pregnancy Complications, Regional Blood Flow
Added March 31, 2018
0 Communities
1 Members
0 Resources
17 MeSH Terms
Inverted formin 2 regulates intracellular trafficking, placentation, and pregnancy outcome.
Lamm KYB, Johnson ML, Baker Phillips J, Muntifering MB, James JM, Jones HN, Redline RW, Rokas A, Muglia LJ
(2018) Elife 7:
MeSH Terms: Animals, Cell Differentiation, Cell Movement, Female, Formins, Mice, Mice, Knockout, Microfilament Proteins, Placentation, Pregnancy, Pregnancy Outcome, Trophoblasts
Added March 21, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms
What is a placental mammal anyway?
Abbot P, Capra JA
(2017) Elife 6:
MeSH Terms: Animals, Eutheria, Evolution, Molecular, Female, Gene Expression Regulation, Developmental, Humans, Lactation, Mammals, Mammary Glands, Human, Marsupialia, Placentation, Pregnancy
Added March 14, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms