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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 18

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Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.
de la Croix Ndong J, Makowski AJ, Uppuganti S, Vignaux G, Ono K, Perrien DS, Joubert S, Baglio SR, Granchi D, Stevenson DA, Rios JJ, Nyman JS, Elefteriou F
(2014) Nat Med 20: 904-10
MeSH Terms: Adolescent, Alkaline Phosphatase, Animals, Bone Development, Bone Diseases, Developmental, Bone Morphogenetic Protein 2, Calcification, Physiologic, Cells, Cultured, Child, Child, Preschool, Collagen Type I, Collagen Type II, Diphosphates, Disease Models, Animal, Durapatite, Humans, Immunoglobulin G, Infant, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitogen-Activated Protein Kinases, Neurofibromatosis 1, Neurofibromin 1, Osteoblasts, Osteogenesis, Phosphate Transport Proteins, Phosphoric Diester Hydrolases, Pyrophosphatases, Recombinant Fusion Proteins, Sp7 Transcription Factor, Transcription Factors
Added July 28, 2014
2 Communities
4 Members
0 Resources
32 MeSH Terms
Autotaxin signaling governs phenotypic heterogeneity in visceral and parietal mesothelia.
Shelton EL, Galindo CL, Williams CH, Pfaltzgraff E, Hong CC, Bader DM
(2013) PLoS One 8: e69712
MeSH Terms: Animals, Cell Line, Tumor, Epithelial Cells, Epithelium, Gene Expression, Genetic Heterogeneity, Humans, Intestine, Small, Lung Neoplasms, Mesothelioma, Mice, Mice, Transgenic, Omentum, Peritoneal Neoplasms, Phenotype, Phosphoric Diester Hydrolases, Pleura, Signal Transduction, Viscera
Added September 20, 2013
2 Communities
3 Members
0 Resources
19 MeSH Terms
Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity.
Zhang R, Jha BK, Ogden KM, Dong B, Zhao L, Elliott R, Patton JT, Silverman RH, Weiss SR
(2013) Proc Natl Acad Sci U S A 110: 13114-9
MeSH Terms: 2',5'-Oligoadenylate Synthetase, Adenine Nucleotides, Amino Acid Sequence, Animals, Binding Sites, Capsid Proteins, Cell Line, Cells, Cultured, Endoribonucleases, Host-Pathogen Interactions, Humans, Immunity, Innate, Immunoblotting, Macrophages, Mice, Mice, Knockout, Molecular Sequence Data, Murine hepatitis virus, Mutation, Oligoribonucleotides, Phosphoric Diester Hydrolases, RNA Virus Infections, RNA Viruses, Rotavirus, Sequence Homology, Amino Acid, Viral Nonstructural Proteins
Added April 3, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
A myelin gene causative of a catatonia-depression syndrome upon aging.
Hagemeyer N, Goebbels S, Papiol S, Kästner A, Hofer S, Begemann M, Gerwig UC, Boretius S, Wieser GL, Ronnenberg A, Gurvich A, Heckers SH, Frahm J, Nave KA, Ehrenreich H
(2012) EMBO Mol Med 4: 528-39
MeSH Terms: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, Adult, Aged, Aging, Animals, Brain, Catatonia, Depression, Female, Humans, Immunohistochemistry, Male, Mice, Microscopy, Middle Aged, Neuroimaging, Phosphoric Diester Hydrolases, Radiography
Added February 12, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Autotaxin and LPA receptors represent potential molecular targets for the radiosensitization of murine glioma through effects on tumor vasculature.
Schleicher SM, Thotala DK, Linkous AG, Hu R, Leahy KM, Yazlovitskaya EM, Hallahan DE
(2011) PLoS One 6: e22182
MeSH Terms: Animals, Cell Death, Cell Line, Tumor, Cell Movement, Cell Survival, Endothelial Cells, Glioma, Human Umbilical Vein Endothelial Cells, Humans, Lysophospholipids, Mice, Molecular Targeted Therapy, Neovascularization, Pathologic, Phosphoric Diester Hydrolases, Radiation-Sensitizing Agents, Receptors, Lysophosphatidic Acid, Signal Transduction
Added August 21, 2013
1 Communities
1 Members
0 Resources
17 MeSH Terms
Autotaxin as a novel serum marker of liver fibrosis.
Nakagawa H, Ikeda H, Nakamura K, Ohkawa R, Masuzaki R, Tateishi R, Yoshida H, Watanabe N, Tejima K, Kume Y, Iwai T, Suzuki A, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Omata M, Igarashi K, Aoki J, Koike K, Yatomi Y
(2011) Clin Chim Acta 412: 1201-6
MeSH Terms: Aged, Area Under Curve, Biomarkers, Female, Hepatitis C, Chronic, Humans, Liver, Liver Cirrhosis, Male, Middle Aged, Multienzyme Complexes, Phosphodiesterase I, Phosphoric Diester Hydrolases, Pyrophosphatases, ROC Curve, Retrospective Studies
Added May 2, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid.
Altman MK, Gopal V, Jia W, Yu S, Hall H, Mills GB, McGinnis AC, Bartlett MG, Jiang G, Madan D, Prestwich GD, Xu Y, Davies MA, Murph MM
(2010) Mol Cancer 9: 140
MeSH Terms: Animals, Antineoplastic Agents, Cell Line, Tumor, Cell Survival, Gene Expression, Humans, Melanoma, Experimental, Mice, Multienzyme Complexes, Phosphatidic Acids, Phosphodiesterase I, Phosphoric Diester Hydrolases, Pyrophosphatases, RNA, Small Interfering, Receptors, Lysophosphatidic Acid, Reverse Transcriptase Polymerase Chain Reaction, Transfection, Xenograft Model Antitumor Assays
Added September 20, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo.
Simon GM, Cravatt BF
(2010) Mol Biosyst 6: 1411-8
MeSH Terms: Animals, Animals, Newborn, Cannabinoid Receptor Modulators, Endocannabinoids, Ethanolamines, Female, Lipid Metabolism, Mice, Mice, Inbred C57BL, Mice, Knockout, Models, Biological, Neurons, Phospholipase D, Phosphoric Diester Hydrolases, Signal Transduction
Added April 10, 2014
0 Communities
0 Members
1 Resources
15 MeSH Terms
Overexpression of the insulin receptor inhibitor PC-1/ENPP1 induces insulin resistance and hyperglycemia.
Maddux BA, Chang YN, Accili D, McGuinness OP, Youngren JF, Goldfine ID
(2006) Am J Physiol Endocrinol Metab 290: E746-9
MeSH Terms: Animals, Blotting, Western, Enzyme-Linked Immunosorbent Assay, Female, Glucose, Glucose Tolerance Test, Humans, Hyperglycemia, Hyperinsulinism, Insulin, Insulin Resistance, Liver, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Muscle, Skeletal, Phosphoric Diester Hydrolases, Pyrophosphatases
Added July 21, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Role of adenosine and nitric oxide on the mechanisms of action of dipyridamole.
Gamboa A, Abraham R, Diedrich A, Shibao C, Paranjape SY, Farley G, Biaggioni I
(2005) Stroke 36: 2170-5
MeSH Terms: Acetylcholine, Adenosine, Adult, Anti-Inflammatory Agents, Non-Steroidal, Aspirin, Blood Flow Velocity, Cardiovascular System, Cross-Over Studies, Cyclic GMP, Dipyridamole, Dose-Response Relationship, Drug, Double-Blind Method, Humans, Models, Biological, Nitric Oxide, Nitroprusside, Phosphoric Diester Hydrolases, Time Factors, Vasodilator Agents
Added December 10, 2013
0 Communities
3 Members
0 Resources
19 MeSH Terms