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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 10

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Myc enhances B-cell receptor signaling in precancerous B cells and confers resistance to Btk inhibition.
Moyo TK, Wilson CS, Moore DJ, Eischen CM
(2017) Oncogene 36: 4653-4661
MeSH Terms: Agammaglobulinaemia Tyrosine Kinase, Animals, B-Lymphocytes, CD79 Antigens, Cell Proliferation, Flow Cytometry, Humans, Lymphoma, Non-Hodgkin, Male, Mice, Mice, Inbred C57BL, Mitogen-Activated Protein Kinase 3, Phosphatidylinositol 3-Kinases, Phospholipase C gamma, Phosphorylation, Precancerous Conditions, Protein-Tyrosine Kinases, Proto-Oncogene Proteins c-myc, Pyrazoles, Pyrimidines, Receptors, Antigen, B-Cell, Splenic Neoplasms, Syk Kinase
Added April 6, 2017
0 Communities
1 Members
0 Resources
23 MeSH Terms
Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling.
Myklebust JH, Brody J, Kohrt HE, Kolstad A, Czerwinski DK, Wälchli S, Green MR, Trøen G, Liestøl K, Beiske K, Houot R, Delabie J, Alizadeh AA, Irish JM, Levy R
(2017) Blood 129: 759-770
MeSH Terms: Agammaglobulinaemia Tyrosine Kinase, CD79 Antigens, Diagnosis, Differential, Flow Cytometry, Gene Expression Regulation, Neoplastic, Humans, Immunoglobulin M, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Follicular, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Phospholipase C gamma, Phosphoproteins, Phosphorylation, Protein-Tyrosine Kinases, Proto-Oncogene Proteins c-akt, Receptors, Antigen, B-Cell, STAT1 Transcription Factor, STAT5 Transcription Factor, Signal Transduction, Single-Cell Analysis, Syk Kinase, p38 Mitogen-Activated Protein Kinases, src-Family Kinases
Added December 31, 2016
1 Communities
1 Members
0 Resources
26 MeSH Terms
HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome.
Gbadegesin RA, Adeyemo A, Webb NJ, Greenbaum LA, Abeyagunawardena A, Thalgahagoda S, Kale A, Gipson D, Srivastava T, Lin JJ, Chand D, Hunley TE, Brophy PD, Bagga A, Sinha A, Rheault MN, Ghali J, Nicholls K, Abraham E, Janjua HS, Omoloja A, Barletta GM, Cai Y, Milford DD, O'Brien C, Awan A, Belostotsky V, Smoyer WE, Homstad A, Hall G, Wu G, Nagaraj S, Wigfall D, Foreman J, Winn MP, Mid-West Pediatric Nephrology Consortium
(2015) J Am Soc Nephrol 26: 1701-10
MeSH Terms: Age Distribution, Age of Onset, Alleles, Case-Control Studies, Child, Child, Preschool, Cohort Studies, Female, Genetic Predisposition to Disease, Genotype, HLA-DQ alpha-Chains, Humans, Incidence, Male, Mutation, Missense, Nephrotic Syndrome, Phospholipase C gamma, Sex Distribution, Sri Lanka, Steroids
Added July 5, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma.
Blix ES, Irish JM, Husebekk A, Delabie J, Forfang L, Tierens AM, Myklebust JH, Kolstad A
(2012) BMC Cancer 12: 478
MeSH Terms: CD40 Antigens, CD40 Ligand, CD79 Antigens, Cluster Analysis, Extracellular Signal-Regulated MAP Kinases, Flow Cytometry, Humans, Interleukins, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, B-Cell, Marginal Zone, Models, Biological, Phospholipase C gamma, Phosphoproteins, Phosphorylation, Receptors, Antigen, B-Cell, STAT5 Transcription Factor, STAT6 Transcription Factor, Signal Transduction, T-Lymphocytes, Transcription Factor RelA
Added February 15, 2013
1 Communities
1 Members
0 Resources
21 MeSH Terms
PLC-gamma1 regulates fibronectin assembly and cell aggregation.
Crooke CE, Pozzi A, Carpenter GF
(2009) Exp Cell Res 315: 2207-14
MeSH Terms: Animals, Cell Aggregation, Cells, Cultured, Culture Media, Conditioned, Deoxycholic Acid, Fibroblasts, Fibronectins, Integrin alpha5beta1, Mice, Mice, Knockout, Phospholipase C gamma
Added February 24, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
Integrin-dependent PLC-gamma1 phosphorylation mediates fibronectin-dependent adhesion.
Tvorogov D, Wang XJ, Zent R, Carpenter G
(2005) J Cell Sci 118: 601-10
MeSH Terms: Animals, Cell Adhesion, Cell Line, Cell Movement, Fibroblasts, Fibronectins, Focal Adhesion Kinase 1, Focal Adhesion Protein-Tyrosine Kinases, Integrin beta1, Integrins, Mice, Mice, Knockout, Phospholipase C gamma, Phosphorylation, Protein Binding, Protein-Tyrosine Kinases, Type C Phospholipases, Tyrosine, src-Family Kinases
Added December 10, 2013
1 Communities
1 Members
0 Resources
19 MeSH Terms
Biochemical differences between SUDHL-1 and KARPAS 299 cells derived from t(2;5)-positive anaplastic large cell lymphoma are responsible for the different sensitivity to the antiproliferative effect of p27(Kip1).
Turturro F, Frist AY, Arnold MD, Seth P, Pulford K
(2001) Oncogene 20: 4466-75
MeSH Terms: Adenoviridae, Apoptosis, Cell Cycle, Cell Cycle Proteins, Chromosomes, Human, Pair 2, Chromosomes, Human, Pair 5, Culture Media, Serum-Free, Cyclin D1, Cyclin-Dependent Kinase Inhibitor p27, Genetic Vectors, Humans, Isoenzymes, Lymphoma, Large B-Cell, Diffuse, Neoplasm Proteins, PTEN Phosphohydrolase, Phospholipase C gamma, Phosphoproteins, Phosphoric Monoester Hydrolases, Phosphorylation, Phosphotyrosine, Protein Processing, Post-Translational, Protein-Serine-Threonine Kinases, Protein-Tyrosine Kinases, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-akt, Recombinant Fusion Proteins, S Phase, Transfection, Translocation, Genetic, Tumor Cells, Cultured, Tumor Suppressor Proteins, Type C Phospholipases
Added April 7, 2010
0 Communities
1 Members
0 Resources
32 MeSH Terms
Systematic analysis of the role of CD19 cytoplasmic tyrosines in enhancement of activation in Daudi human B cells: clustering of phospholipase C and Vav and of Grb2 and Sos with different CD19 tyrosines.
Brooks SR, Li X, Volanakis EJ, Carter RH
(2000) J Immunol 164: 3123-31
MeSH Terms: Adaptor Proteins, Signal Transducing, Adjuvants, Immunologic, Antigens, CD19, B-Lymphocytes, Calcium Signaling, Cell Cycle Proteins, Cytoplasm, Exons, GRB2 Adaptor Protein, Humans, Isoenzymes, Lymphocyte Activation, MAP Kinase Signaling System, Mitogen-Activated Protein Kinase 1, Molecular Weight, Mutagenesis, Site-Directed, Peptide Mapping, Phospholipase C gamma, Phosphopeptides, Proteins, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-vav, Receptors, Antigen, B-Cell, Son of Sevenless Protein, Drosophila, Tumor Cells, Cultured, Type C Phospholipases, Tyrosine, Vanadates
Added May 27, 2014
0 Communities
1 Members
0 Resources
28 MeSH Terms
Phosphoinositide 3-kinase regulates phospholipase Cgamma-mediated calcium signaling.
Rameh LE, Rhee SG, Spokes K, Kazlauskas A, Cantley LC, Cantley LG
(1998) J Biol Chem 273: 23750-7
MeSH Terms: Androstadienes, Binding Sites, Calcium, Chromones, Enzyme Inhibitors, Humans, Isoenzymes, Kinetics, Morpholines, Phosphatidylinositol 3-Kinases, Phosphatidylinositol Phosphates, Phospholipase C gamma, Platelet-Derived Growth Factor, Receptors, Platelet-Derived Growth Factor, Recombinant Fusion Proteins, Signal Transduction, Transfection, Tumor Cells, Cultured, Type C Phospholipases, Wortmannin
Added November 26, 2018
0 Communities
1 Members
0 Resources
20 MeSH Terms
Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development.
Ji QS, Winnier GE, Niswender KD, Horstman D, Wisdom R, Magnuson MA, Carpenter G
(1997) Proc Natl Acad Sci U S A 94: 2999-3003
MeSH Terms: Animals, Cells, Cultured, Embryonic and Fetal Development, Gene Targeting, Genotype, Heterozygote, Isoenzymes, Mice, Phospholipase C gamma, Protein-Tyrosine Kinases, Signal Transduction, Stem Cells, Substrate Specificity, Type C Phospholipases
Added February 23, 2011
2 Communities
2 Members
0 Resources
14 MeSH Terms