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Results: 1 to 10 of 73

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Uncovering matrix effects on lipid analyses in MALDI imaging mass spectrometry experiments.
Perry WJ, Patterson NH, Prentice BM, Neumann EK, Caprioli RM, Spraggins JM
(2020) J Mass Spectrom 55: e4491
MeSH Terms: 2-Naphthylamine, Acetophenones, Animals, Fourier Analysis, Gentisates, Lipids, Liver, Mice, Phosphatidylcholines, Phosphatidylethanolamines, Principal Component Analysis, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Added January 22, 2020
0 Communities
2 Members
0 Resources
12 MeSH Terms
Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Conformation, and Inhibits γ-Secretase Nonselectively in Liposomes.
Kamp F, Scheidt HA, Winkler E, Basset G, Heinel H, Hutchison JM, LaPointe LM, Sanders CR, Steiner H, Huster D
(2018) ACS Chem Neurosci 9: 1702-1713
MeSH Terms: Amyloid Precursor Protein Secretases, Amyloid beta-Protein Precursor, Bexarotene, Cholesterol, HEK293 Cells, Humans, Liposomes, Molecular Structure, Neuroprotective Agents, Phosphatidylcholines, Protein Conformation, alpha-Helical, Protein Domains, Receptor, Notch1, Static Electricity
Added November 21, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
Evaluation of Collision Cross Section Calibrants for Structural Analysis of Lipids by Traveling Wave Ion Mobility-Mass Spectrometry.
Hines KM, May JC, McLean JA, Xu L
(2016) Anal Chem 88: 7329-36
MeSH Terms: Calibration, Ions, Nitrogen, Peptides, Phosphatidylcholines, Phosphatidylethanolamines, Spectrometry, Mass, Electrospray Ionization
Added December 17, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin Repair.
Natarajan C, Yao SY, Sriram S
(2016) PLoS One 11: e0152163
MeSH Terms: Animals, Cell Differentiation, Cell Nucleus, Cell Polarity, Cells, Cultured, Corpus Callosum, Enzyme Activation, Intercellular Signaling Peptides and Proteins, Interleukin-33, Lysophosphatidylcholines, Macrophages, Models, Biological, Myelin Basic Protein, Myelin Sheath, Neuroglia, Oligodendroglia, Phenotype, Phosphorylation, Poly I-C, Rats, Sprague-Dawley, Real-Time Polymerase Chain Reaction, Recombinant Proteins, Stem Cells, Toll-Like Receptor 3, Transcription, Genetic, Up-Regulation, Wound Healing, p38 Mitogen-Activated Protein Kinases
Added April 18, 2017
0 Communities
1 Members
0 Resources
28 MeSH Terms
Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles.
Schlebach JP, Barrett PJ, Day CA, Kim JH, Kenworthy AK, Sanders CR
(2016) Biochemistry 55: 985-8
MeSH Terms: Amyloid beta-Protein Precursor, Caveolin 3, Cholesterol, Fluorescent Dyes, Humans, Hydrophobic and Hydrophilic Interactions, Membrane Microdomains, Microscopy, Confocal, Microscopy, Fluorescence, Models, Molecular, Myelin Proteins, Peptide Fragments, Phosphatidylcholines, Phosphatidylethanolamines, Protein Conformation, Protein Interaction Domains and Motifs, Recombinant Proteins, Rhodamines, Sphingomyelins, Unilamellar Liposomes
Added February 12, 2016
0 Communities
2 Members
0 Resources
20 MeSH Terms
Apolipoprotein A-V is present in bile and its secretion increases with lipid absorption in Sprague-Dawley rats.
Zhang LS, Sato H, Yang Q, Ryan RO, Wang DQ, Howles PN, Tso P
(2015) Am J Physiol Gastrointest Liver Physiol 309: G918-25
MeSH Terms: Animals, Apolipoprotein A-V, Apolipoproteins, Bile, Biliary Fistula, Chylomicrons, Disease Models, Animal, Duodenum, Emulsions, Fasting, Intestinal Absorption, Liver, Lymph, Male, Phosphatidylcholines, Phospholipids, Rats, Sprague-Dawley, Soybean Oil, Taurocholic Acid, Time Factors, Up-Regulation
Added December 8, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Vinyl sulfone analogs of lysophosphatidylcholine irreversibly inhibit autotaxin and prevent angiogenesis in melanoma.
Murph MM, Jiang GW, Altman MK, Jia W, Nguyen DT, Fambrough JM, Hardman WJ, Nguyen HT, Tran SK, Alshamrani AA, Madan D, Zhang J, Prestwich GD
(2015) Bioorg Med Chem 23: 5999-6013
MeSH Terms: Cell Line, Tumor, Humans, Lysophosphatidylcholines, Melanoma, Neovascularization, Pathologic, Sulfones
Added September 20, 2016
0 Communities
1 Members
0 Resources
6 MeSH Terms
Notch Transmembrane Domain: Secondary Structure and Topology.
Deatherage CL, Lu Z, Kim JH, Sanders CR
(2015) Biochemistry 54: 3565-8
MeSH Terms: Humans, Lipid Bilayers, Lysophosphatidylcholines, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Peptide Fragments, Phosphatidylcholines, Protein Conformation, Protein Structure, Secondary, Protein Structure, Tertiary, Receptor, Notch1, Recombinant Proteins, Surface Properties
Added February 5, 2016
1 Communities
1 Members
0 Resources
13 MeSH Terms
Structural investigation of the transmembrane domain of KCNE1 in proteoliposomes.
Sahu ID, Kroncke BM, Zhang R, Dunagan MM, Smith HJ, Craig A, McCarrick RM, Sanders CR, Lorigan GA
(2014) Biochemistry 53: 6392-401
MeSH Terms: Amino Acid Substitution, Humans, Lipid Bilayers, Liposomes, Molecular Dynamics Simulation, Phosphatidylcholines, Phosphatidylglycerols, Potassium Channels, Voltage-Gated, Protein Structure, Secondary, Protein Structure, Tertiary, Thermodynamics
Added November 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion.
Perrin BS, Tian Y, Fu R, Grant CV, Chekmenev EY, Wieczorek WE, Dao AE, Hayden RM, Burzynski CM, Venable RM, Sharma M, Opella SJ, Pastor RW, Cotten ML
(2014) J Am Chem Soc 136: 3491-504
MeSH Terms: Antimicrobial Cationic Peptides, Fish Proteins, Hydrophobic and Hydrophilic Interactions, Immersion, Lipid Bilayers, Liquid Crystals, Molecular Dynamics Simulation, Phosphatidylcholines, Phosphatidylglycerols, Protein Structure, Secondary
Added March 5, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms