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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 17

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Recent Structural Insights into Cytochrome P450 Function.
Guengerich FP, Waterman MR, Egli M
(2016) Trends Pharmacol Sci 37: 625-640
MeSH Terms: Cytochrome P-450 Enzyme System, Humans, Models, Molecular, Pharmaceutical Preparations, Pharmacokinetics, Structure-Activity Relationship
Added March 14, 2018
0 Communities
1 Members
0 Resources
6 MeSH Terms
Pharmacokinetic assessment in patients receiving continuous RRT: perspectives from the Kidney Health Initiative.
Nolin TD, Aronoff GR, Fissell WH, Jain L, Madabushi R, Reynolds K, Zhang L, Huang SM, Mehrotra R, Flessner MF, Leypoldt JK, Witcher JW, Zineh I, Archdeacon P, Roy-Chaudhury P, Goldstein SL, Kidney Health Initiative
(2015) Clin J Am Soc Nephrol 10: 159-64
MeSH Terms: Acute Kidney Injury, Critical Illness, Drug Dosage Calculations, Humans, Nephrology, Pharmaceutical Preparations, Pharmacokinetics, Renal Replacement Therapy
Added October 28, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Machine learning-based prediction of drug-drug interactions by integrating drug phenotypic, therapeutic, chemical, and genomic properties.
Cheng F, Zhao Z
(2014) J Am Med Inform Assoc 21: e278-86
MeSH Terms: Artificial Intelligence, Bayes Theorem, Decision Trees, Drug Interactions, Humans, Logistic Models, Models, Theoretical, Molecular Structure, Pharmaceutical Preparations, Pharmacokinetics, ROC Curve, Support Vector Machine
Added May 27, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Computational methods in drug discovery.
Sliwoski G, Kothiwale S, Meiler J, Lowe EW
(2014) Pharmacol Rev 66: 334-95
MeSH Terms: Animals, Computer-Aided Design, Drug Discovery, Drug-Related Side Effects and Adverse Reactions, Humans, Ligands, Molecular Structure, Pharmaceutical Preparations, Pharmacokinetics
Added January 24, 2015
1 Communities
1 Members
0 Resources
9 MeSH Terms
Introduction: use of radioactive compounds in drug discovery and development.
Guengerich FP
(2012) Chem Res Toxicol 25: 511-2
MeSH Terms: Animals, Drug Discovery, Humans, Pharmaceutical Preparations, Pharmacokinetics, Radioisotopes
Added March 7, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
Drug dosing consideration in patients with acute and chronic kidney disease-a clinical update from Kidney Disease: Improving Global Outcomes (KDIGO).
Matzke GR, Aronoff GR, Atkinson AJ, Bennett WM, Decker BS, Eckardt KU, Golper T, Grabe DW, Kasiske B, Keller F, Kielstein JT, Mehta R, Mueller BA, Pasko DA, Schaefer F, Sica DA, Inker LA, Umans JG, Murray P
(2011) Kidney Int 80: 1122-37
MeSH Terms: Dose-Response Relationship, Drug, Government Agencies, Humans, Kidney Diseases, Pharmacokinetics, Practice Guidelines as Topic, Renal Replacement Therapy
Added August 7, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms
Genome-wide association studies in pharmacogenomics: successes and lessons.
Motsinger-Reif AA, Jorgenson E, Relling MV, Kroetz DL, Weinshilboum R, Cox NJ, Roden DM
(2013) Pharmacogenet Genomics 23: 383-94
MeSH Terms: Case-Control Studies, Chromosome Mapping, Cohort Studies, Diagnosis, Genome-Wide Association Study, Genotype, Humans, Linear Models, Pharmacogenetics, Pharmacokinetics, Phenotype, Therapeutics
Added March 7, 2014
0 Communities
2 Members
0 Resources
12 MeSH Terms
Update information on drug metabolism systems--2009, part II: summary of information on the effects of diseases and environmental factors on human cytochrome P450 (CYP) enzymes and transporters.
Rendic S, Guengerich FP
(2010) Curr Drug Metab 11: 4-84
MeSH Terms: Biotransformation, Carrier Proteins, Cytochrome P-450 Enzyme System, Disease, Drug Design, Environment, Female, Gene Expression Regulation, Genotype, Humans, Isoenzymes, Male, Metabolomics, Pharmaceutical Preparations, Pharmacokinetics, Phenotype, Polymorphism, Genetic, Systems Biology, Systems Integration
Added March 26, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Validation of bioluminescent imaging techniques.
Virostko J, Jansen ED
(2009) Methods Mol Biol 574: 15-23
MeSH Terms: Animals, Biological Availability, Fireflies, Luciferases, Luminescence, Pharmacokinetics, Substrate Specificity
Added January 20, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms
Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors.
Stevens KL, Alligood KJ, Alberti JG, Caferro TR, Chamberlain SD, Dickerson SH, Dickson HD, Emerson HK, Griffin RJ, Hubbard RD, Keith BR, Mullin RJ, Petrov KG, Gerding RM, Reno MJ, Rheault TR, Rusnak DW, Sammond DM, Smith SC, Uehling DE, Waterson AG, Wood ER
(2009) Bioorg Med Chem Lett 19: 21-6
MeSH Terms: Administration, Oral, Animals, Antineoplastic Agents, ErbB Receptors, Mice, Pharmacokinetics, Pyrimidines, Pyrrolidines, Receptor, ErbB-2, Structure-Activity Relationship
Added March 5, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms