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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 30

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Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury.
Yang Y, Yang H, Wang Z, Varadaraj K, Kumari SS, Mergler S, Okada Y, Saika S, Kingsley PJ, Marnett LJ, Reinach PS
(2013) Cell Signal 25: 501-11
MeSH Terms: Animals, Arachidonic Acids, Benzoxazines, Calcium, Calcium Channel Blockers, Cell Line, Disease Models, Animal, Endocannabinoids, Epithelial Cells, Epithelium, Corneal, Glycerides, Humans, Immunity, Innate, MAP Kinase Kinase Kinases, Mice, Mice, Knockout, Mitogen-Activated Protein Kinase 8, Morpholines, Naphthalenes, Patch-Clamp Techniques, Pertussis Toxin, Protein Binding, RNA Interference, RNA, Small Interfering, Receptor, Cannabinoid, CB1, Signal Transduction, TRPV Cation Channels, Wound Healing
Added June 1, 2014
0 Communities
1 Members
0 Resources
28 MeSH Terms
Dysregulation of dopamine transporters via dopamine D2 autoreceptors triggers anomalous dopamine efflux associated with attention-deficit hyperactivity disorder.
Bowton E, Saunders C, Erreger K, Sakrikar D, Matthies HJ, Sen N, Jessen T, Colbran RJ, Caron MG, Javitch JA, Blakely RD, Galli A
(2010) J Neurosci 30: 6048-57
MeSH Terms: Animals, Attention Deficit Disorder with Hyperactivity, Brain, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Cell Line, Dopamine, Dopamine Plasma Membrane Transport Proteins, Genetic Variation, Humans, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Neurons, Neurotransmitter Agents, Pertussis Toxin, Phosphorylation, Receptors, Dopamine D2, Signal Transduction
Added December 10, 2013
1 Communities
3 Members
0 Resources
19 MeSH Terms
A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors.
Niswender CM, Johnson KA, Luo Q, Ayala JE, Kim C, Conn PJ, Weaver CD
(2008) Mol Pharmacol 73: 1213-24
MeSH Terms: Adrenergic Agonists, Allosteric Regulation, Amino Acids, Animals, Biological Assay, Carbachol, Cell Line, Dose-Response Relationship, Drug, G Protein-Coupled Inwardly-Rectifying Potassium Channels, GTP-Binding Protein alpha Subunits, Gi-Go, Humans, Ion Channel Gating, Ligands, Muscarinic Agonists, Pertussis Toxin, Rats, Receptors, Metabotropic Glutamate, Receptors, Muscarinic, Reproducibility of Results, Thallium, Xanthenes
Added February 16, 2015
0 Communities
3 Members
0 Resources
21 MeSH Terms
Serotonin 5-HT1A receptor stimulates c-Jun N-terminal kinase and induces apoptosis in Chinese hamster ovary fibroblasts.
Turner JH, Garnovskaya MN, Raymond JR
(2007) Biochim Biophys Acta 1773: 391-9
MeSH Terms: 8-Hydroxy-2-(di-n-propylamino)tetralin, Animals, Apoptosis, CHO Cells, Chromatin, Cricetinae, Cricetulus, Enzyme Activation, Extracellular Signal-Regulated MAP Kinases, Fibroblasts, GTP-Binding Protein alpha Subunits, Gi-Go, Gene Expression Regulation, Humans, JNK Mitogen-Activated Protein Kinases, Molecular Weight, Pertussis Toxin, Piperazines, Pyridines, Receptor, Serotonin, 5-HT1A, Serotonin 5-HT1 Receptor Antagonists, rho GTP-Binding Proteins
Added July 23, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Characterization of a rabbit kidney prostaglandin F(2{alpha}) receptor exhibiting G(i)-restricted signaling that inhibits water absorption in the collecting duct.
H├ębert RL, Carmosino M, Saito O, Yang G, Jackson CA, Qi Z, Breyer RM, Natarajan C, Hata AN, Zhang Y, Guan Y, Breyer MD
(2005) J Biol Chem 280: 35028-37
MeSH Terms: Amino Acid Sequence, Animals, Base Sequence, Calcium, Cell Line, Cloning, Molecular, DNA, Complementary, Dinoprost, Female, GTP-Binding Protein alpha Subunits, Gi-Go, Genetic Vectors, Humans, In Situ Hybridization, Kidney, Kidney Tubules, Collecting, Lac Operon, Latanoprost, Ligands, Molecular Sequence Data, Ovary, Perfusion, Pertussis Toxin, Prostaglandins, Prostaglandins F, Synthetic, Protein Binding, RNA, Messenger, Rabbits, Reverse Transcriptase Polymerase Chain Reaction, Ribonucleases, Sequence Homology, Amino Acid, Signal Transduction, Time Factors, Tissue Distribution, Transfection, Water
Added December 21, 2013
0 Communities
1 Members
0 Resources
35 MeSH Terms
Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.
McLaughlin JN, Shen L, Holinstat M, Brooks JD, Dibenedetto E, Hamm HE
(2005) J Biol Chem 280: 25048-59
MeSH Terms: Actins, Adenosine Diphosphate, Amides, Calcium, Cells, Cultured, Chelating Agents, Dipeptides, Dose-Response Relationship, Drug, Egtazic Acid, Electric Impedance, Endothelium, Vascular, Enzyme Inhibitors, GTP-Binding Protein alpha Subunits, G12-G13, GTP-Binding Protein alpha Subunits, Gq-G11, GTP-Binding Proteins, Humans, Intracellular Signaling Peptides and Proteins, Kinetics, Ligands, Matrix Metalloproteinase Inhibitors, Microcirculation, Models, Biological, Models, Theoretical, Peptides, Pertussis Toxin, Protease Inhibitors, Protein Binding, Protein-Serine-Threonine Kinases, Pyridines, Receptor, PAR-1, Signal Transduction, Thrombin, Time Factors, rho-Associated Kinases
Added December 10, 2013
0 Communities
1 Members
0 Resources
34 MeSH Terms
Thrombin modulates the expression of a set of genes including thrombospondin-1 in human microvascular endothelial cells.
McLaughlin JN, Mazzoni MR, Cleator JH, Earls L, Perdigoto AL, Brooks JD, Muldowney JA, Vaughan DE, Hamm HE
(2005) J Biol Chem 280: 22172-80
MeSH Terms: Adenosine Diphosphate, Algorithms, Amides, Apoptosis, Cells, Cultured, Cluster Analysis, Culture Media, DNA Primers, DNA, Complementary, Dose-Response Relationship, Drug, Electric Impedance, Endothelium, Vascular, Enzyme-Linked Immunosorbent Assay, Extracellular Matrix, GTP-Binding Protein alpha Subunits, Gi-Go, GTP-Binding Protein alpha Subunits, Gq-G11, Gene Expression Regulation, Humans, Indoles, Maleimides, Microcirculation, Models, Biological, Nucleic Acid Hybridization, Oligonucleotide Array Sequence Analysis, Peptides, Pertussis Toxin, Promoter Regions, Genetic, Protein Binding, Pyridines, RNA, Receptor, PAR-1, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Thrombin, Thrombospondin 1, Time Factors, Umbilical Veins, Up-Regulation
Added December 10, 2013
0 Communities
1 Members
0 Resources
38 MeSH Terms
Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy.
Maruyama Y, Nishida M, Sugimoto Y, Tanabe S, Turner JH, Kozasa T, Wada T, Nagao T, Kurose H
(2002) Circ Res 91: 961-9
MeSH Terms: ADP Ribose Transferases, Adaptor Proteins, Signal Transducing, Adenoviridae, Animals, Animals, Newborn, Botulinum Toxins, Cardiomegaly, Carrier Proteins, Cells, Cultured, DNA-Binding Proteins, Enzyme Activation, Enzyme Inhibitors, GTP-Binding Protein alpha Subunits, G12-G13, GTP-Binding Protein alpha Subunits, Gq-G11, Heterotrimeric GTP-Binding Proteins, JNK Mitogen-Activated Protein Kinases, Mitogen-Activated Protein Kinases, Myocardium, Oxidants, Peptide Fragments, Pertussis Toxin, Protein Subunits, Rats, Rats, Sprague-Dawley, Receptors, Adrenergic, alpha-1, Signal Transduction, Transfection, rhoA GTP-Binding Protein
Added July 23, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Antibody-induced activation of beta1 integrin receptors stimulates cAMP-dependent migration of breast cells on laminin-5.
Plopper GE, Huff JL, Rust WL, Schwartz MA, Quaranta V
(2000) Mol Cell Biol Res Commun 4: 129-35
MeSH Terms: Adenosine Diphosphate Ribose, Antibodies, Monoclonal, Breast Neoplasms, Cell Adhesion, Cell Adhesion Molecules, Cell Movement, Cells, Cultured, Cyclic AMP, DNA Primers, Female, Heterotrimeric GTP-Binding Proteins, Humans, Integrin alpha3beta1, Integrins, Pertussis Toxin, Precipitin Tests, Receptors, Laminin, Signal Transduction, Tumor Cells, Cultured, Virulence Factors, Bordetella
Added March 27, 2014
1 Communities
1 Members
0 Resources
20 MeSH Terms
The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity.
Addison CL, Daniel TO, Burdick MD, Liu H, Ehlert JE, Xue YY, Buechi L, Walz A, Richmond A, Strieter RM
(2000) J Immunol 165: 5269-77
MeSH Terms: Administration, Topical, Amino Acid Motifs, Amino Acid Sequence, Angiogenesis Inhibitors, Animals, Antibodies, Blocking, Cell Migration Inhibition, Cells, Cultured, Chemokines, CXC, Cornea, Endothelium, Vascular, Humans, Immune Sera, Mice, Mice, Inbred C57BL, Mice, Knockout, Microcirculation, Molecular Sequence Data, Neovascularization, Physiologic, Pertussis Toxin, Rats, Receptors, Interleukin-8B, Virulence Factors, Bordetella
Added May 31, 2013
2 Communities
1 Members
0 Resources
23 MeSH Terms