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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 14

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The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Fischer K, Fenzl A, Liu D, Dyar KA, Kleinert M, Brielmeier M, Clemmensen C, Fedl A, Finan B, Gessner A, Jastroch M, Huang J, Keipert S, Klingenspor M, Brüning JC, Kneilling M, Maier FC, Othman AE, Pichler BJ, Pramme-Steinwachs I, Sachs S, Scheideler A, Thaiss WM, Uhlenhaut H, Ussar S, Woods SC, Zorn J, Stemmer K, Collins S, Diaz-Meco M, Moscat J, Tschöp MH, Müller TD
(2020) Nat Commun 11: 2306
MeSH Terms: Activating Transcription Factor 2, Adipogenesis, Adipose Tissue, Brown, Adipose Tissue, White, Animals, Cell Nucleus, Magnetic Resonance Imaging, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Obesity, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Positron Emission Tomography Computed Tomography, Protein Binding, Sequestosome-1 Protein, Uncoupling Protein 1, p38 Mitogen-Activated Protein Kinases
Added July 22, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.
Yu G, Tzouvelekis A, Wang R, Herazo-Maya JD, Ibarra GH, Srivastava A, de Castro JPW, DeIuliis G, Ahangari F, Woolard T, Aurelien N, Arrojo E Drigo R, Gan Y, Graham M, Liu X, Homer RJ, Scanlan TS, Mannam P, Lee PJ, Herzog EL, Bianco AC, Kaminski N
(2018) Nat Med 24: 39-49
MeSH Terms: Animals, Cells, Cultured, Epithelium, Female, Humans, Iodide Peroxidase, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria, Molecular Mimicry, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Protein Kinases, Pulmonary Fibrosis, Thyroid Hormones
Added April 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis.
Alvarez-Garcia O, Matsuzaki T, Olmer M, Plate L, Kelly JW, Lotz MK
(2017) Arthritis Rheumatol 69: 1418-1428
MeSH Terms: AMP-Activated Protein Kinases, Animals, Apoptosis, Arthritis, Experimental, Autophagy, Autophagy-Related Protein 5, Cartilage, Articular, Chondrocytes, DNA-Binding Proteins, Disease Models, Animal, High Mobility Group Proteins, Humans, Immunohistochemistry, Menisci, Tibial, Mice, Mice, Knockout, Microtubule-Associated Proteins, Mitochondria, Organelle Biogenesis, Osteoarthritis, Knee, Oxidative Stress, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Synovial Membrane, Transcription Factors
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Activation of MAPK and FoxO by manganese (Mn) in rat neonatal primary astrocyte cultures.
Exil V, Ping L, Yu Y, Chakraborty S, Caito SW, Wells KS, Karki P, Lee E, Aschner M
(2014) PLoS One 9: e94753
MeSH Terms: Active Transport, Cell Nucleus, Animals, Animals, Newborn, Astrocytes, Cell Nucleus, Cells, Cultured, Enzyme Activation, Enzyme Induction, Forkhead Box Protein O3, Forkhead Transcription Factors, Manganese, Mitogen-Activated Protein Kinases, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Phosphorylation, Proto-Oncogene Proteins c-akt, Pyrrolidonecarboxylic Acid, Rats, Rats, Sprague-Dawley, Reactive Oxygen Species, Signal Transduction, Superoxide Dismutase, Thiazolidines, Time Factors, Transcription Factors
Added April 11, 2016
0 Communities
1 Members
0 Resources
24 MeSH Terms
β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.
Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE
(2014) Cell Metab 19: 96-108
MeSH Terms: Adipocytes, Brown, Adipocytes, White, Adipose Tissue, Brown, Adipose Tissue, White, Aminoisobutyric Acids, Animals, Cardiovascular Diseases, Cell Differentiation, Exercise, Gene Expression Regulation, Glucose Tolerance Test, Humans, Induced Pluripotent Stem Cells, Liver, Metabolic Diseases, Mice, Organ Specificity, Oxidation-Reduction, PPAR alpha, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Phenotype, Physical Conditioning, Animal, Risk Factors, Transcription Factors, Transcription, Genetic, Weight Gain
Added February 28, 2014
1 Communities
1 Members
0 Resources
26 MeSH Terms
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.
Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, Bell EL, Sinclair DA
(2013) Cell 155: 1624-38
MeSH Terms: AMP-Activated Protein Kinases, Aging, Animals, Cell Nucleus, Hypoxia-Inducible Factor 1, alpha Subunit, Mice, Mitochondria, Muscle, Skeletal, NAD, Oxidative Phosphorylation, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Reactive Oxygen Species, Sirtuin 1, Transcription Factors
Added March 4, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Phenotypic and molecular differences between rats selectively bred to voluntarily run high vs. low nightly distances.
Roberts MD, Brown JD, Company JM, Oberle LP, Heese AJ, Toedebusch RG, Wells KD, Cruthirds CL, Knouse JA, Ferreira JA, Childs TE, Brown M, Booth FW
(2013) Am J Physiol Regul Integr Comp Physiol 304: R1024-35
MeSH Terms: Absorptiometry, Photon, Animals, Body Composition, DNA, Complementary, Eating, Female, Hindlimb, Male, Muscle Fibers, Skeletal, Muscle, Skeletal, NAD, Nucleus Accumbens, Organ Size, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Phenotype, Physical Conditioning, Animal, RNA, Messenger, RNA-Binding Proteins, Rats, Rats, Wistar, Real-Time Polymerase Chain Reaction, Running, Sex Characteristics, Transcription Factors
Added October 23, 2017
0 Communities
1 Members
0 Resources
24 MeSH Terms
Telomeres and mitochondria in the aging heart.
Moslehi J, DePinho RA, Sahin E
(2012) Circ Res 110: 1226-37
MeSH Terms: Age Factors, Aging, Animals, Cardiovascular Diseases, Carrier Proteins, Energy Metabolism, Heat-Shock Proteins, Humans, Mitochondria, Heart, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, RNA-Binding Proteins, Signal Transduction, Telomerase, Telomere, Telomere Shortening, Transcription Factors, Tumor Suppressor Protein p53
Added March 4, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
HTR1B, ADIPOR1, PPARGC1A, and CYP19A1 and obesity in a cohort of Caucasians and African Americans: an evaluation of gene-environment interactions and candidate genes.
Edwards TL, Velez Edwards DR, Villegas R, Cohen SS, Buchowski MS, Fowke JH, Schlundt D, Long J, Long JR, Cai Q, Zheng W, Shu XO, Hargreaves MK, Smith J, Jeffrey S, Williams SM, Signorello LB, Blot WJ, Matthews CE
(2012) Am J Epidemiol 175: 11-21
MeSH Terms: African Americans, Alcohol Drinking, Aromatase, Body Mass Index, Energy Intake, European Continental Ancestry Group, Female, Gene-Environment Interaction, Genetic Association Studies, Heat-Shock Proteins, Humans, Linear Models, Male, Middle Aged, Motor Activity, Obesity, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Polymorphism, Single Nucleotide, Prospective Studies, Receptor, Serotonin, 5-HT1B, Receptors, Adiponectin, Risk Factors, Smoking, Transcription Factors
Added December 10, 2013
0 Communities
9 Members
0 Resources
24 MeSH Terms
Mitochondrial content and distribution changes specific to mouse diaphragm after chronic normobaric hypoxia.
Gamboa JL, Andrade FH
(2010) Am J Physiol Regul Integr Comp Physiol 298: R575-83
MeSH Terms: Animals, Atmospheric Pressure, Autophagy, Blotting, Western, Chronic Disease, Diaphragm, Electron Transport Complex IV, Hypoxia, Male, Membrane Proteins, Mice, Mice, Inbred C57BL, Microscopy, Electron, Mitochondria, Mitochondrial Proteins, Muscle, Skeletal, Oxygen, PPAR gamma, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, RNA, Messenger, Trans-Activators, Transcription Factors
Added April 25, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms