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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 62

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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, Wynn DT, Yang F, Garcia-Contreras M, Williams CH, Dakshanamurthy S, Hong CC, Ayad NG, Capobianco AJ, Ahmed Y, Lee E, Robbins DJ
(2021) Nat Commun 12: 5263
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Casein Kinase Ialpha, Drosophila Proteins, Drosophila melanogaster, Embryo, Nonmammalian, Evolution, Molecular, HEK293 Cells, Humans, Immunologic Factors, Lenalidomide, Mice, Organoids, Peptide Hydrolases, Ubiquitin-Protein Ligases, Ubiquitination, Wnt Signaling Pathway, Zebrafish, Zebrafish Proteins
Added September 11, 2021
0 Communities
1 Members
0 Resources
19 MeSH Terms
Cuts Both Ways: Proteases Modulate Virulence of Enterohemorrhagic .
Palmer LD, Skaar EP
(2019) mBio 10:
MeSH Terms: Enterohemorrhagic Escherichia coli, Escherichia coli Proteins, Humans, Microbiota, Peptide Hydrolases, Virulence
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
DNPEP is not the only peptidase that produces SPAK fragments in kidney.
Koumangoye R, Delpire E
(2017) Physiol Rep 5:
MeSH Terms: Animals, CRISPR-Cas Systems, Female, Glutamyl Aminopeptidase, Kidney, Male, Mice, Mice, Knockout, Peptide Hydrolases, Protein-Serine-Threonine Kinases
Added February 15, 2018
1 Communities
1 Members
0 Resources
10 MeSH Terms
Defining the interaction of the protease CpaA with its type II secretion chaperone CpaB and its contribution to virulence in species.
Kinsella RL, Lopez J, Palmer LD, Salinas ND, Skaar EP, Tolia NH, Feldman MF
(2017) J Biol Chem 292: 19628-19638
MeSH Terms: Acinetobacter, Animals, Factor V, Larva, Mice, Mice, Inbred C57BL, Molecular Chaperones, Peptide Hydrolases, Protein Binding, Proteolysis, Spleen, Virulence
Added March 15, 2018
0 Communities
1 Members
0 Resources
12 MeSH Terms
Antagonistic roles for the ubiquitin ligase Asr1 and the ubiquitin-specific protease Ubp3 in subtelomeric gene silencing.
McCann TS, Guo Y, McDonald WH, Tansey WP
(2016) Proc Natl Acad Sci U S A 113: 1309-14
MeSH Terms: Chromatography, Affinity, Gene Silencing, Peptide Hydrolases, Saccharomyces cerevisiae Proteins, Telomere, Ubiquitin-Protein Ligases
Added January 26, 2016
0 Communities
2 Members
0 Resources
6 MeSH Terms
The capability of Pseudomonas aeruginosa to recruit zinc under conditions of limited metal availability is affected by inactivation of the ZnuABC transporter.
D'Orazio M, Mastropasqua MC, Cerasi M, Pacello F, Consalvo A, Chirullo B, Mortensen B, Skaar EP, Ciavardelli D, Pasquali P, Battistoni A
(2015) Metallomics 7: 1023-35
MeSH Terms: Alginates, Animals, Bacterial Proteins, Female, Genes, Bacterial, Glucuronic Acid, Hexuronic Acids, Membrane Transport Proteins, Mice, Inbred C57BL, Mutation, Peptide Hydrolases, Pseudomonas Infections, Pseudomonas aeruginosa, Zinc
Added February 8, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Thermolysin damages animal life through degradation of plasma proteins enhanced by rapid cleavage of serpins and activation of proteases.
Kong L, Lu A, Guan J, Yang B, Li M, Hillyer JF, Ramarao N, Söderhäll K, Liu C, Ling E
(2015) Arch Insect Biochem Physiol 88: 64-84
MeSH Terms: Animals, Blood Proteins, Bombyx, Catechol Oxidase, Drosophila melanogaster, Enzyme Precursors, Hemolymph, Insect Proteins, Larva, Melanins, Peptide Hydrolases, Serine Endopeptidases, Serine Proteases, Serpins, Thermolysin, Virulence Factors
Added February 5, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity.
Stobart CC, Sexton NR, Munjal H, Lu X, Molland KL, Tomar S, Mesecar AD, Denison MR
(2013) J Virol 87: 12611-8
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Chimera, Conserved Sequence, Coronavirus, Coronavirus Infections, Cricetinae, Evolution, Molecular, Humans, Mice, Molecular Sequence Data, Peptide Hydrolases, Phylogeny, Protein Structure, Tertiary, Sequence Alignment, Viral Proteins
Added February 19, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Synthetic and tissue-derived models for studying rigidity effects on invadopodia activity.
Weaver AM, Page JM, Guelcher SA, Parekh A
(2013) Methods Mol Biol 1046: 171-89
MeSH Terms: Actins, Cell Line, Tumor, Extracellular Matrix, Humans, Molecular Biology, Neoplasm Metastasis, Neoplasms, Peptide Hydrolases, Proteolysis, Substrate Specificity
Added March 10, 2014
2 Communities
3 Members
0 Resources
10 MeSH Terms
Thick-tissue bioreactor as a platform for long-term organotypic culture and drug delivery.
Markov DA, Lu JQ, Samson PC, Wikswo JP, McCawley LJ
(2012) Lab Chip 12: 4560-8
MeSH Terms: Bioreactors, Cell Culture Techniques, Cells, Cultured, Docetaxel, Drug Delivery Systems, Epithelial Cells, Equipment Design, Humans, Microfluidic Analytical Techniques, Peptide Hydrolases, Protease Inhibitors, Structure-Activity Relationship, Taxoids
Added March 7, 2014
1 Communities
2 Members
0 Resources
13 MeSH Terms