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Results: 1 to 4 of 4

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Co-treatment with ginsenoside Rh2 and betulinic acid synergistically induces apoptosis in human cancer cells in association with enhanced capsase-8 activation, bax translocation, and cytochrome c release.
Li Q, Li Y, Wang X, Fang X, He K, Guo X, Zhan Z, Sun C, Jin YH
(2011) Mol Carcinog 50: 760-9
MeSH Terms: Antineoplastic Agents, Phytogenic, Apoptosis, BH3 Interacting Domain Death Agonist Protein, Blotting, Western, Caspase 3, Caspase 8, Caspase 9, Cell Line, Tumor, Cell Survival, Cytochromes c, Dose-Response Relationship, Drug, Drug Synergism, Enzyme Activation, Flow Cytometry, Ginsenosides, HeLa Cells, Hep G2 Cells, Humans, Molecular Structure, Neoplasms, Pentacyclic Triterpenes, Poly(ADP-ribose) Polymerases, Protein Transport, RNA Interference, Triterpenes, bcl-2-Associated X Protein
Added July 28, 2015
0 Communities
1 Members
0 Resources
26 MeSH Terms
Betulinic acid derivatives as HIV-1 antivirals.
Aiken C, Chen CH
(2005) Trends Mol Med 11: 31-6
MeSH Terms: Anti-HIV Agents, HIV-1, Humans, Pentacyclic Triterpenes, Triterpenes, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
6 MeSH Terms
Bifunctional anti-human immunodeficiency virus type 1 small molecules with two novel mechanisms of action.
Huang L, Yuan X, Aiken C, Chen CH
(2004) Antimicrob Agents Chemother 48: 663-5
MeSH Terms: Animals, Anti-HIV Agents, COS Cells, Chlorocebus aethiops, HIV Core Protein p24, HIV Envelope Protein gp120, HIV-1, Pentacyclic Triterpenes, Structure-Activity Relationship, Triterpenes, Virus Replication
Added February 19, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Gene expression changes in the human fibroblast induced by Centella asiatica triterpenoids.
Coldren CD, Hashim P, Ali JM, Oh SK, Sinskey AJ, Rha C
(2003) Planta Med 69: 725-32
MeSH Terms: Cell Line, Centella, Dose-Response Relationship, Drug, Fibroblasts, Gene Expression Regulation, Humans, Pentacyclic Triterpenes, Phytotherapy, RNA, Terpenes, Triterpenes, Wound Healing
Added November 17, 2011
0 Communities
1 Members
0 Resources
12 MeSH Terms