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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 15

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Novel Small Molecule JP-153 Targets the Src-FAK-Paxillin Signaling Complex to Inhibit VEGF-Induced Retinal Angiogenesis.
Toutounchian JJ, Pagadala J, Miller DD, Baudry J, Park F, Chaum E, Morales-Tirado , Yates CR
(2017) Mol Pharmacol 91: 1-13
MeSH Terms: Animals, Benzoxazines, Cell Movement, Cell Proliferation, Disease Models, Animal, Endothelial Cells, Focal Adhesion Protein-Tyrosine Kinases, Humans, Mice, Inbred C57BL, Models, Biological, Oxygen, Paxillin, Retinal Neovascularization, Signal Transduction, Small Molecule Libraries, Vascular Endothelial Growth Factor A, src-Family Kinases
Added June 11, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin.
Theodosiou M, Widmaier M, Böttcher RT, Rognoni E, Veelders M, Bharadwaj M, Lambacher A, Austen K, Müller DJ, Zent R, Fässler R
(2016) Elife 5: e10130
MeSH Terms: Animals, Cell Adhesion, Cell Line, Cell Movement, Cytoskeletal Proteins, Fibroblasts, Focal Adhesion Protein-Tyrosine Kinases, Integrin beta1, Manganese, Mice, Muscle Proteins, Paxillin, Protein Binding, Talin
Added February 4, 2016
1 Communities
1 Members
0 Resources
14 MeSH Terms
Automated analysis of cell-matrix adhesions in 2D and 3D environments.
Broussard JA, Diggins NL, Hummel S, Georgescu W, Quaranta V, Webb DJ
(2015) Sci Rep 5: 8124
MeSH Terms: Algorithms, Animals, Automation, Cell Culture Techniques, Cell Line, Tumor, Cell-Matrix Junctions, Collagen Type I, Green Fluorescent Proteins, Humans, Image Processing, Computer-Assisted, Paxillin, Rats, Reproducibility of Results, Time-Lapse Imaging
Added February 19, 2015
2 Communities
2 Members
0 Resources
14 MeSH Terms
Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice.
Moik D, Böttcher A, Makhina T, Grashoff C, Bulus N, Zent R, Fässler R
(2013) J Biol Chem 288: 18863-71
MeSH Terms: Amino Acid Motifs, Animals, Binding Sites, Cell Adhesion, Cell Movement, Embryo, Mammalian, Flow Cytometry, Focal Adhesions, Gene Expression Regulation, Developmental, Genes, Lethal, Mice, Microfilament Proteins, Mutation, Paxillin, Protein Binding, Protein Conformation, Protein Structure, Tertiary, Protein-Serine-Threonine Kinases, Time Factors
Added December 10, 2013
1 Communities
1 Members
0 Resources
19 MeSH Terms
Role of cyclic nucleotide-dependent actin cytoskeletal dynamics:Ca(2+)](i) and force suppression in forskolin-pretreated porcine coronary arteries.
Hocking KM, Baudenbacher FJ, Putumbaka G, Venkatraman S, Cheung-Flynn J, Brophy CM, Komalavilas P
(2013) PLoS One 8: e60986
MeSH Terms: Actin Cytoskeleton, Actin Depolymerizing Factors, Actins, Animals, Biomechanical Phenomena, Calcium, Cell Adhesion Molecules, Colforsin, Coronary Vessels, HSP20 Heat-Shock Proteins, Histamine, Intracellular Space, Microfilament Proteins, Muscle Contraction, Myosin Light Chains, Nucleotides, Cyclic, Paxillin, Phosphoproteins, Phosphorylation, Sus scrofa
Added March 9, 2015
0 Communities
2 Members
0 Resources
20 MeSH Terms
Expression of focal adhesion kinase in small-cell lung carcinoma.
Ocak S, Chen H, Callison C, Gonzalez AL, Massion PP
(2012) Cancer 118: 1293-301
MeSH Terms: Aged, Female, Focal Adhesion Kinase 1, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms, Male, Middle Aged, Neoplasm Staging, Paxillin, Phosphorylation, Small Cell Lung Carcinoma, Survival Analysis
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Dynamics and mechanism of p130Cas localization to focal adhesions.
Donato DM, Ryzhova LM, Meenderink LM, Kaverina I, Hanks SK
(2010) J Biol Chem 285: 20769-79
MeSH Terms: Animals, Antibodies, Monoclonal, Cell Movement, Crk-Associated Substrate Protein, Fibroblasts, Focal Adhesions, Genes, Reporter, Genetic Variation, Immunoblotting, Luminescent Proteins, Mice, Paxillin, Phosphorylation, Plasmids, Polymerase Chain Reaction, Substrate Specificity, Wound Healing, src-Family Kinases
Added December 10, 2013
0 Communities
2 Members
0 Resources
18 MeSH Terms
Significance of microtubule catastrophes at focal adhesion sites.
Efimov A, Kaverina I
(2009) Cell Adh Migr 3: 285-7
MeSH Terms: Cell Movement, Focal Adhesions, Humans, Microtubules, Models, Biological, Paxillin
Added December 10, 2013
0 Communities
1 Members
0 Resources
6 MeSH Terms
A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes.
Hagan GN, Lin Y, Magnuson MA, Avruch J, Czech MP
(2008) Mol Cell Biol 28: 4215-26
MeSH Terms: 3T3-L1 Cells, Actins, Adipocytes, Animals, Carrier Proteins, Cell Membrane Structures, Cells, Cultured, Enzyme Activation, Fibroblasts, Humans, Immunoprecipitation, Insulin, Mice, Myosin Type I, Myosins, Paxillin, Phosphatidylinositol 3-Kinases, Phosphotyrosine, Protein Binding, Protein Kinases, Protein Structure, Tertiary, Proto-Oncogene Proteins c-akt, Rapamycin-Insensitive Companion of mTOR Protein, Sirolimus, TOR Serine-Threonine Kinases
Added August 22, 2011
3 Communities
1 Members
0 Resources
25 MeSH Terms
Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites.
Efimov A, Schiefermeier N, Grigoriev I, Ohi R, Brown MC, Turner CE, Small JV, Kaverina I
(2008) J Cell Sci 121: 196-204
MeSH Terms: Animals, Cell Adhesion, Cell Movement, Cytoplasm, Cytoskeletal Proteins, Fibroblasts, Gene Expression Regulation, Glutathione Transferase, Goldfish, Microscopy, Fluorescence, Microscopy, Video, Microtubules, Models, Biological, Paxillin, Protein Structure, Tertiary
Added December 10, 2013
0 Communities
2 Members
0 Resources
15 MeSH Terms