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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 156

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Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state.
Taylor KC, Kang PW, Hou P, Yang ND, Kuenze G, Smith JA, Shi J, Huang H, White KM, Peng D, George AL, Meiler J, McFeeters RL, Cui J, Sanders CR
(2020) Elife 9:
MeSH Terms: Animals, Electrophysiology, Fluorometry, Humans, KCNQ1 Potassium Channel, Magnetic Resonance Spectroscopy, Oocytes, Patch-Clamp Techniques, Protein Structure, Tertiary, Xenopus laevis
Added March 3, 2020
0 Communities
2 Members
0 Resources
10 MeSH Terms
Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers.
Trads JB, Hüll K, Matsuura BS, Laprell L, Fehrentz T, Görldt N, Kozek KA, Weaver CD, Klöcker N, Barber DM, Trauner D
(2019) Angew Chem Int Ed Engl 58: 15421-15428
MeSH Terms: Action Potentials, Azo Compounds, Cyclization, Drug Design, G Protein-Coupled Inwardly-Rectifying Potassium Channels, HEK293 Cells, Humans, Isomerism, Lidocaine, Light, Patch-Clamp Techniques, Potassium Channel Blockers, Thermodynamics
Added March 27, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion.
Dickerson MT, Dadi PK, Altman MK, Verlage KR, Thorson AS, Jordan KL, Vierra NC, Amarnath G, Jacobson DA
(2019) Am J Physiol Endocrinol Metab 316: E646-E659
MeSH Terms: Alkanes, Animals, Apamin, Calcium, Calcium Channels, Calcium Channels, L-Type, Calcium Channels, P-Type, Calcium Channels, Q-Type, Endoplasmic Reticulum, Glucagon, Glucagon-Secreting Cells, Glucose, Mice, Mice, Transgenic, Patch-Clamp Techniques, Peptides, Potassium Channel Blockers, Potassium Channels, Calcium-Activated, Pyrazoles, Quinolinium Compounds
Added February 13, 2019
0 Communities
1 Members
0 Resources
20 MeSH Terms
α-Adrenergic Receptor Activation Decreases Parabrachial Nucleus Excitatory Drive onto BNST CRF Neurons and Reduces Their Activity .
Fetterly TL, Basu A, Nabit BP, Awad E, Williford KM, Centanni SW, Matthews RT, Silberman Y, Winder DG
(2019) J Neurosci 39: 472-484
MeSH Terms: Adrenergic alpha-2 Receptor Agonists, Animals, Corticotropin-Releasing Hormone, Female, Gene Expression, Genes, fos, Guanfacine, Male, Mice, Mice, Inbred C57BL, Neurons, Norepinephrine, Ovariectomy, Parabrachial Nucleus, Patch-Clamp Techniques, Protein Kinase C-delta, Receptors, Adrenergic, alpha-2, Receptors, G-Protein-Coupled, Restraint, Physical, Septal Nuclei, Stress, Psychological
Added March 26, 2019
0 Communities
1 Members
0 Resources
21 MeSH Terms
PF-06827443 Displays Robust Allosteric Agonist and Positive Allosteric Modulator Activity in High Receptor Reserve and Native Systems.
Moran SP, Cho HP, Maksymetz J, Remke DH, Hanson RM, Niswender CM, Lindsley CW, Rook JM, Conn PJ
(2018) ACS Chem Neurosci 9: 2218-2224
MeSH Terms: Allosteric Regulation, Animals, CHO Cells, Calcium, Cricetulus, Dogs, Humans, Isoindoles, Mice, Oxazoles, Patch-Clamp Techniques, Prefrontal Cortex, Rats, Receptor, Muscarinic M1, Seizures
Added March 3, 2020
0 Communities
2 Members
0 Resources
MeSH Terms
Simultaneous Real-Time Measurement of the β-Cell Membrane Potential and Ca Influx to Assess the Role of Potassium Channels on β-Cell Function.
Vierra NC, Dickerson MT, Philipson LH, Jacobson DA
(2018) Methods Mol Biol 1684: 73-84
MeSH Terms: Animals, Calcium, Cells, Cultured, Humans, Insulin-Secreting Cells, Membrane Potentials, Mice, Patch-Clamp Techniques, Potassium Channels
Added November 13, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
Overexpressing wild-type γ2 subunits rescued the seizure phenotype in Gabrg2 Dravet syndrome mice.
Huang X, Zhou C, Tian M, Kang JQ, Shen W, Verdier K, Pimenta A, MacDonald RL
(2017) Epilepsia 58: 1451-1461
MeSH Terms: Action Potentials, Animals, Convulsants, Electric Stimulation, Epilepsies, Myoclonic, Humans, In Vitro Techniques, Inhibitory Postsynaptic Potentials, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Mutation, Neural Pathways, Patch-Clamp Techniques, Pentylenetetrazole, Protein Subunits, Pyramidal Cells, Receptors, GABA-A, Somatosensory Cortex, Thalamus
Added June 21, 2017
1 Communities
0 Members
0 Resources
21 MeSH Terms
Optical control of GIRK channels using visible light.
Trads JB, Burgstaller J, Laprell L, Konrad DB, de la Osa de la Rosa L, Weaver CD, Baier H, Trauner D, Barber DM
(2016) Org Biomol Chem 15: 76-81
MeSH Terms: Azo Compounds, G Protein-Coupled Inwardly-Rectifying Potassium Channels, HEK293 Cells, Humans, Light, Patch-Clamp Techniques, Photochemical Processes
Added April 3, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Contrasting Nav1.8 Activity in Scn10a-/- Ventricular Myocytes and the Intact Heart.
Stroud DM, Yang T, Bersell K, Kryshtal DO, Nagao S, Shaffer C, Short L, Hall L, Atack TC, Zhang W, Knollmann BC, Baudenbacher F, Roden DM
(2016) J Am Heart Assoc 5:
MeSH Terms: Action Potentials, Animals, Electrocardiography, Heart, Heart Ventricles, Isolated Heart Preparation, Mice, Mice, Knockout, Myocardium, Myocytes, Cardiac, NAV1.8 Voltage-Gated Sodium Channel, Patch-Clamp Techniques, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction
Added February 3, 2017
1 Communities
2 Members
0 Resources
14 MeSH Terms
Identification and Functional Assessment of Age-Dependent Truncations to Cx46 and Cx50 in the Human Lens.
Slavi N, Wang Z, Harvey L, Schey KL, Srinivas M
(2016) Invest Ophthalmol Vis Sci 57: 5714-5722
MeSH Terms: Aging, Cataract, Cell Membrane Permeability, Cells, Cultured, Connexins, Humans, Lens, Crystalline, Membrane Glycoproteins, Middle Aged, Patch-Clamp Techniques, Tandem Mass Spectrometry
Added May 6, 2017
0 Communities
1 Members
0 Resources
11 MeSH Terms