Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 18

Publication Record

Connections

Multiple actions of parathyroid hormone-related protein in breast cancer bone metastasis.
Martin TJ, Johnson RW
(2021) Br J Pharmacol 178: 1923-1935
MeSH Terms: Bone Neoplasms, Bone and Bones, Humans, Osteoclasts, Parathyroid Hormone, Parathyroid Hormone-Related Protein
Added March 3, 2020
0 Communities
1 Members
0 Resources
6 MeSH Terms
Hedgehog and TGFβ signaling converge on Gli2 to control bony invasion and bone destruction in oral squamous cell carcinoma.
Cannonier SA, Gonzales CB, Ely K, Guelcher SA, Sterling JA
(2016) Oncotarget 7: 76062-76075
MeSH Terms: Animals, Bone and Bones, Carcinoma, Squamous Cell, Cell Line, Tumor, Disease Models, Animal, Gene Expression, Hedgehog Proteins, Heterografts, Humans, Mice, Mouth Neoplasms, Neoplasm Invasiveness, Nuclear Proteins, Parathyroid Hormone-Related Protein, Signal Transduction, Transforming Growth Factor beta, Zinc Finger Protein Gli2
Added April 26, 2017
0 Communities
2 Members
0 Resources
17 MeSH Terms
Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer.
Johnson RW, Merkel AR, Page JM, Ruppender NS, Guelcher SA, Sterling JA
(2014) Clin Exp Metastasis 31: 945-59
MeSH Terms: Animals, Blotting, Western, Bone Neoplasms, Breast Neoplasms, Female, Gene Expression Regulation, Humans, Kruppel-Like Transcription Factors, Lung Neoplasms, Mice, Mice, Nude, Nuclear Proteins, Parathyroid Hormone-Related Protein, Promoter Regions, Genetic, RNA, Messenger, RNA, Small Interfering, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Stromal Cells, Transforming Growth Factor beta, Tumor Cells, Cultured, Wnt3A Protein, Xenograft Model Antitumor Assays, Zinc Finger Protein Gli2, beta Catenin
Added February 12, 2015
1 Communities
3 Members
0 Resources
26 MeSH Terms
Parathyroid hormone-related protein drives a CD11b+Gr1+ cell-mediated positive feedback loop to support prostate cancer growth.
Park SI, Lee C, Sadler WD, Koh AJ, Jones J, Seo JW, Soki FN, Cho SW, Daignault SD, McCauley LK
(2013) Cancer Res 73: 6574-83
MeSH Terms: Animals, Antigens, Surface, Bone Marrow Cells, CD11b Antigen, Cell Line, Tumor, Cell Proliferation, Dogs, Feedback, Physiological, Humans, Male, Mice, Mice, Nude, Parathyroid Hormone-Related Protein, Prostatic Neoplasms, Tumor Microenvironment
Added March 5, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Parathyroid hormone-related protein inhibits DKK1 expression through c-Jun-mediated inhibition of β-catenin activation of the DKK1 promoter in prostate cancer.
Zhang H, Yu C, Dai J, Keller JM, Hua A, Sottnik JL, Shelley G, Hall CL, Park SI, Yao Z, Zhang J, McCauley LK, Keller ET
(2014) Oncogene 33: 2464-77
MeSH Terms: Blotting, Western, Cell Line, Tumor, Chromatin Immunoprecipitation, Gene Expression Regulation, Neoplastic, Gene Knockdown Techniques, Humans, Intercellular Signaling Peptides and Proteins, Male, Parathyroid Hormone-Related Protein, Promoter Regions, Genetic, Prostatic Neoplasms, Proto-Oncogene Proteins c-jun, RNA, Small Interfering, Real-Time Polymerase Chain Reaction, Wnt Signaling Pathway, beta Catenin
Added March 5, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
The multifaceted actions of PTHrP in skeletal metastasis.
Soki FN, Park SI, McCauley LK
(2012) Future Oncol 8: 803-17
MeSH Terms: Anoikis, Apoptosis, Bone Neoplasms, Bone and Bones, Cell Movement, Cell Proliferation, Cellular Microenvironment, Humans, Hypercalcemia, Intercellular Signaling Peptides and Proteins, Parathyroid Hormone-Related Protein, Tumor Microenvironment
Added March 5, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Nuclear localization of parathyroid hormone-related peptide confers resistance to anoikis in prostate cancer cells.
Park SI, McCauley LK
(2012) Endocr Relat Cancer 19: 243-54
MeSH Terms: Animals, Anoikis, Bone Neoplasms, Cell Line, Tumor, Cell Nucleus, Gene Knockdown Techniques, Humans, Male, Mice, Mice, Nude, Neoplasm Transplantation, Parathyroid Hormone-Related Protein, Prostatic Neoplasms, Tumor Necrosis Factor-alpha
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
6-Thioguanine inhibition of parathyroid hormone-related protein expression is mediated by GLI2.
Johnson RW, Merkel AR, Danilin S, Nguyen MP, Mundy GR, Sterling JA
(2011) Anticancer Res 31: 2705-12
MeSH Terms: Cell Line, Tumor, Cell Proliferation, Humans, Kruppel-Like Transcription Factors, Nuclear Proteins, Parathyroid Hormone-Related Protein, RNA, Messenger, Reverse Transcriptase Polymerase Chain Reaction, Thioguanine, Zinc Finger Protein Gli2
Added March 12, 2014
0 Communities
2 Members
0 Resources
10 MeSH Terms
Bone structural components regulating sites of tumor metastasis.
Sterling JA, Guelcher SA
(2011) Curr Osteoporos Rep 9: 89-95
MeSH Terms: Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Bone Density Conservation Agents, Bone Neoplasms, Breast Neoplasms, Denosumab, Diphosphonates, Female, Humans, Kruppel-Like Transcription Factors, Male, Nuclear Proteins, Parathyroid Hormone-Related Protein, RANK Ligand, Transforming Growth Factor beta, Zinc Finger Protein Gli2, rho-Associated Kinases
Added March 5, 2014
1 Communities
2 Members
0 Resources
17 MeSH Terms
TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling.
Johnson RW, Nguyen MP, Padalecki SS, Grubbs BG, Merkel AR, Oyajobi BO, Matrisian LM, Mundy GR, Sterling JA
(2011) Cancer Res 71: 822-31
MeSH Terms: Animals, Bone Neoplasms, Breast Neoplasms, Female, Hedgehog Proteins, Humans, Kruppel-Like Transcription Factors, Mice, Mice, Nude, Nuclear Proteins, Parathyroid Hormone-Related Protein, Recombinant Proteins, Signal Transduction, Transforming Growth Factor beta, Veratrum Alkaloids, Zinc Finger Protein Gli2
Added March 5, 2014
0 Communities
2 Members
0 Resources
16 MeSH Terms