p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate.
Nyeng P, Heilmann S, Löf-Öhlin ZM, Pettersson NF, Hermann FM, Reynolds AB, Semb H
(2019) Dev Cell 49
: 31-47.e9MeSH Terms: Animals, Body Patterning, Cadherins, Catenins, Cell Differentiation, Cell Lineage, Cell Movement, Embryonic Development, Flow Cytometry, Gene Expression Regulation, Developmental, Humans, Islets of Langerhans, Mice, Pancreas, Pancreatic Ducts, Receptors, Notch, Signal Transduction, Stem CellsAdded March 29, 2019
18 MeSH Terms
ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice.
Kimura Y, Fukuda A, Ogawa S, Maruno T, Takada Y, Tsuda M, Hiramatsu Y, Araki O, Nagao M, Yoshikawa T, Ikuta K, Yoshioka T, Wang Z, Akiyama H, Wright CV, Takaori K, Uemoto S, Chiba T, Seno H
(2018) Gastroenterology 155
: 194-209.e2MeSH Terms: Adenocarcinoma in Situ, Animals, Carcinogenesis, Carcinoma, Pancreatic Ductal, Cell Culture Techniques, Cell Differentiation, DNA-Binding Proteins, Mice, Nuclear Proteins, Pancreatic Ducts, Pancreatic Neoplasms, Proto-Oncogene Proteins p21(ras), SOX9 Transcription Factor, Transcription FactorsAdded April 3, 2018
14 MeSH Terms
Alpha to Beta Cell Reprogramming: Stepping toward a New Treatment for Diabetes.
Osipovich AB, Magnuson MA
(2018) Cell Stem Cell 22
: 12-13MeSH Terms: Animals, Cellular Reprogramming, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Homeodomain Proteins, Insulin, Insulin-Secreting Cells, Mice, Pancreatic DuctsAdded January 8, 2018
9 MeSH Terms
Pancreatic Inflammation Redirects Acinar to β Cell Reprogramming.
Clayton HW, Osipovich AB, Stancill JS, Schneider JD, Vianna PG, Shanks CM, Yuan W, Gu G, Manduchi E, Stoeckert CJ, Magnuson MA
(2016) Cell Rep 17
: 2028-2041MeSH Terms: Acinar Cells, Adenoviridae, Alleles, Animals, Cellular Reprogramming, Diabetes Mellitus, Experimental, Doxycycline, Gene Expression Profiling, Homeodomain Proteins, Immunity, Inflammation, Insulin-Secreting Cells, Macrophages, Metaplasia, Mice, Transgenic, Organ Size, Pancreas, Pancreatic Ducts, Reproducibility of Results, Transcription Factors, TransgenesAdded November 18, 2016
21 MeSH Terms
Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells.
Sancho R, Gruber R, Gu G, Behrens A
(2014) Cell Stem Cell 15
: 139-53MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Differentiation, Cell Line, Tumor, Cell Lineage, F-Box Proteins, F-Box-WD Repeat-Containing Protein 7, Gene Deletion, Gene Expression Profiling, Gene Expression Regulation, Developmental, Glucagon-Secreting Cells, Glucose, HEK293 Cells, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice, Multipotent Stem Cells, Nerve Tissue Proteins, Pancreatic Ducts, Proteasome Endopeptidase Complex, Regeneration, Somatostatin-Secreting Cells, Ubiquitin-Protein Ligases, UbiquitinationAdded January 23, 2015
26 MeSH Terms
Partial duct ligation: β-cell proliferation and beyond.
Van de Casteele M, Leuckx G, Cai Y, Yuchi Y, Coppens V, De Groef S, Van Gassen N, Baeyens L, Heremans Y, Wright CV, Heimberg H
(2014) Diabetes 63
: 2567-77MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Proliferation, Gene Expression Regulation, Insulin-Secreting Cells, Ligation, Male, Mice, Models, Animal, Nerve Tissue Proteins, Pancreatic DuctsAdded January 20, 2015
11 MeSH Terms
Differentiation of pancreatic ductal adenocarcinoma from chronic pancreatitis by PAM4 immunohistochemistry.
Shi C, Merchant N, Newsome G, Goldenberg DM, Gold DV
(2014) Arch Pathol Lab Med 138
: 220-8MeSH Terms: Antigens, Neoplasm, Biomarkers, Tumor, Carcinoma, Pancreatic Ductal, Diagnosis, Differential, Humans, Immunohistochemistry, Mucin-1, Neoplasm Grading, Neoplasm Staging, Pancreas, Pancreatectomy, Pancreatic Cyst, Pancreatic Ducts, Pancreatic Neoplasms, Pancreatitis, Chronic, Precancerous Conditions, Tissue Array AnalysisAdded March 10, 2014
17 MeSH Terms
Identification and manipulation of biliary metaplasia in pancreatic tumors.
Delgiorno KE, Hall JC, Takeuchi KK, Pan FC, Halbrook CJ, Washington MK, Olive KP, Spence JR, Sipos B, Wright CV, Wells JM, Crawford HC
(2014) Gastroenterology 146
: 233-44.e5MeSH Terms: Animals, Bile Ducts, Carcinoma, Pancreatic Ductal, Cell Transformation, Neoplastic, HMGB Proteins, Humans, Metaplasia, Mice, Mice, Transgenic, Pancreatic Ducts, Pancreatic Neoplasms, Pancreatitis, Precancerous Conditions, Proto-Oncogene Proteins p21(ras), SOXF Transcription Factors, Signal TransductionAdded January 17, 2014
16 MeSH Terms
Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes.
Al-Hasani K, Pfeifer A, Courtney M, Ben-Othman N, Gjernes E, Vieira A, Druelle N, Avolio F, Ravassard P, Leuckx G, Lacas-Gervais S, Ambrosetti D, Benizri E, Hecksher-Sorensen J, Gounon P, Ferrer J, Gradwohl G, Heimberg H, Mansouri A, Collombat P
(2013) Dev Cell 26
: 86-100MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Blood Glucose, Cell Differentiation, Cell Lineage, Cell Movement, Cellular Reprogramming, Diabetes Mellitus, Experimental, Epithelial-Mesenchymal Transition, Gene Expression Regulation, Glucagon-Secreting Cells, Homeodomain Proteins, Hypertrophy, Insulin-Secreting Cells, Mice, Nerve Tissue Proteins, Paired Box Transcription Factors, Pancreatic Ducts, StreptozocinAdded August 14, 2013
19 MeSH Terms
Dynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformation.
Westmoreland JJ, Drosos Y, Kelly J, Ye J, Means AL, Washington MK, Sosa-Pineda B
(2012) Dev Dyn 241
: 583-94MeSH Terms: Animals, Cell Transformation, Neoplastic, Claudins, Epithelium, Humans, Mice, Mice, Inbred C57BL, Morphogenesis, Organogenesis, Pancreas, Pancreatic Ducts, Pancreatic Neoplasms, Tumor Cells, CulturedAdded July 19, 2013
13 MeSH Terms