p16(Ink4a)-induced senescence of pancreatic beta cells enhances insulin secretion.Helman A, Klochendler A, Azazmeh N, Gabai Y, Horwitz E, Anzi S, Swisa A, Condiotti R, Granit RZ, Nevo Y, Fixler Y, Shreibman D, Zamir A, Tornovsky-Babeay S, Dai C, Glaser B, Powers AC, Shapiro AM, Magnuson MA, Dor Y, Ben-Porath I
(2016)
Nat Med 22: 412-20
MeSH Terms: Aging, Animals, Cell Proliferation, Cellular Senescence, Cyclin-Dependent Kinase Inhibitor p16, Fibroblasts, Gene Expression Regulation, Glucose, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice, Mice, Transgenic, PPAR gamma, TOR Serine-Threonine KinasesAdded March 17, 2016