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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 10

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The peroxisome proliferator-activated receptor-β/δ antagonist GSK0660 mitigates retinal cell inflammation and leukostasis.
Capozzi ME, Savage SR, McCollum GW, Hammer SS, Ramos CJ, Yang R, Bretz CA, Penn JS
(2020) Exp Eye Res 190: 107885
MeSH Terms: Adult, Animals, Cells, Cultured, Cytokines, Endothelial Cells, Ependymoglial Cells, Humans, Inflammation, Leukostasis, Male, Mice, Mice, Inbred C57BL, PPAR delta, PPAR-beta, Palmitic Acids, Real-Time Polymerase Chain Reaction, Retina, Retinitis, Sulfones, Thiophenes
Added March 30, 2020
0 Communities
1 Members
0 Resources
20 MeSH Terms
RNA-seq identifies a role for the PPARβ/δ inverse agonist GSK0660 in the regulation of TNFα-induced cytokine signaling in retinal endothelial cells.
Savage SR, McCollum GW, Yang R, Penn JS
(2015) Mol Vis 21: 568-76
MeSH Terms: Cells, Cultured, Chemokine CCL8, Cytokines, Endothelial Cells, Gene Expression Regulation, Humans, PPAR delta, PPAR-beta, Retinal Vessels, Sequence Analysis, RNA, Signal Transduction, Sulfones, Thiophenes, Tumor Necrosis Factor-alpha
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use.
Liu S, Brown JD, Stanya KJ, Homan E, Leidl M, Inouye K, Bhargava P, Gangl MR, Dai L, Hatano B, Hotamisligil GS, Saghatelian A, Plutzky J, Lee CH
(2013) Nature 502: 550-4
MeSH Terms: Acetyl-CoA Carboxylase, Animals, Circadian Rhythm, Diabetes Mellitus, Fatty Acids, Gene Expression Regulation, Homeostasis, Lipids, Lipogenesis, Liver, Male, Mice, Mice, Inbred C57BL, Muscles, Obesity, PPAR delta, Phosphatidylcholines, Principal Component Analysis
Added September 6, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
Peroxisome proliferator-activated receptor-β/δ regulates angiogenic cell behaviors and oxygen-induced retinopathy.
Capozzi ME, McCollum GW, Savage SR, Penn JS
(2013) Invest Ophthalmol Vis Sci 54: 4197-207
MeSH Terms: Angiogenesis Inhibitors, Animals, Cells, Cultured, Disease Models, Animal, Endothelial Cells, Humans, Oxygen, PPAR delta, PPAR-beta, Rats, Retinal Diseases, Retinal Neovascularization, Retinal Vessels, Sulfones, Thiazoles, Thiophenes
Added October 9, 2013
1 Communities
1 Members
0 Resources
16 MeSH Terms
Neuron-specific deletion of peroxisome proliferator-activated receptor delta (PPARδ) in mice leads to increased susceptibility to diet-induced obesity.
Kocalis HE, Turney MK, Printz RL, Laryea GN, Muglia LJ, Davies SS, Stanwood GD, McGuinness OP, Niswender KD
(2012) PLoS One 7: e42981
MeSH Terms: Animals, Body Composition, Brain, Diet, Fat-Restricted, Diet, High-Fat, Eating, Energy Metabolism, Female, Lipid Metabolism, Male, Mice, Mice, Knockout, Obesity, PPAR delta
Added December 10, 2013
4 Communities
4 Members
1 Resources
14 MeSH Terms
Peroxisome proliferator-activated receptor delta (PPARD) genetic variation and type 2 diabetes in middle-aged Chinese women.
Villegas R, Williams S, Gao Y, Cai Q, Li H, Elasy T, Cai H, Edwards T, Xiang YB, Zheng W, Long J, Ou Shu X
(2011) Ann Hum Genet 75: 621-9
MeSH Terms: Adult, Aged, Asian Continental Ancestry Group, Body Mass Index, Diabetes Mellitus, Type 2, Female, Genome-Wide Association Study, Humans, Middle Aged, Motor Activity, PPAR delta, Polymorphism, Single Nucleotide
Added December 10, 2013
0 Communities
3 Members
0 Resources
12 MeSH Terms
β-Catenin and p120 mediate PPARδ-dependent proliferation induced by Helicobacter pylori in human and rodent epithelia.
Nagy TA, Wroblewski LE, Wang D, Piazuelo MB, Delgado A, Romero-Gallo J, Noto J, Israel DA, Ogden SR, Correa P, Cover TL, Peek RM
(2011) Gastroenterology 141: 553-64
MeSH Terms: Adenocarcinoma, Animals, Antigens, Bacterial, Bacterial Proteins, Catenins, Cell Proliferation, Cell Transformation, Neoplastic, Cells, Cultured, Cyclin E, Epithelial Cells, Gastric Mucosa, Gerbillinae, Helicobacter Infections, Helicobacter pylori, Humans, Ki-67 Antigen, Oncogene Proteins, PPAR delta, Signal Transduction, Stomach Neoplasms, beta Catenin
Added July 26, 2012
1 Communities
5 Members
0 Resources
21 MeSH Terms
Peroxisome proliferator-activated receptor beta/delta expression and activation in lung cancer.
Pedchenko TV, Gonzalez AL, Wang D, DuBois RN, Massion PP
(2008) Am J Respir Cell Mol Biol 39: 689-96
MeSH Terms: Adult, Aged, Aged, 80 and over, Apoptosis, Cell Adhesion, Cell Line, Tumor, Cell Proliferation, Cell Survival, Cyclooxygenase 2, Female, Humans, Immunohistochemistry, Ligands, Lung, Lung Neoplasms, Male, Middle Aged, PPAR delta, PPAR-beta, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Signal Transduction, Tissue Array Analysis
Added March 5, 2014
0 Communities
2 Members
0 Resources
23 MeSH Terms
Extracellular signal-regulated kinase is a target of cyclooxygenase-1-peroxisome proliferator-activated receptor-delta signaling in epithelial ovarian cancer.
Daikoku T, Tranguch S, Chakrabarty A, Wang D, Khabele D, Orsulic S, Morrow JD, Dubois RN, Dey SK
(2007) Cancer Res 67: 5285-92
MeSH Terms: Animals, Anti-Inflammatory Agents, Non-Steroidal, Aspirin, Cell Growth Processes, Cell Line, Tumor, Cyclooxygenase 1, Cyclooxygenase Inhibitors, Enzyme Activation, Epithelial Cells, Epoprostenol, Female, Humans, Male, Mice, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Ovarian Neoplasms, PPAR delta, Pyrazoles, Signal Transduction, Xenograft Model Antitumor Assays
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha.
Yu Z, Schneider C, Boeglin WE, Brash AR
(2007) Lipids 42: 491-7
MeSH Terms: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid, 8,11,14-Eicosatrienoic Acid, Arachidonate Lipoxygenases, Cell Differentiation, Cell Line, Epidermal Cells, Epidermis, Genes, Reporter, Humans, Hydroxyeicosatetraenoic Acids, Lipoxygenase, Luciferases, PPAR alpha, PPAR delta, PPAR gamma, Receptors, Cytoplasmic and Nuclear, Signal Transduction
Added December 10, 2013
0 Communities
2 Members
0 Resources
17 MeSH Terms