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Results: 1 to 10 of 16

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Insm1, Neurod1, and Pax6 promote murine pancreatic endocrine cell development through overlapping yet distinct RNA transcription and splicing programs.
Dudek KD, Osipovich AB, Cartailler JP, Gu G, Magnuson MA
(2021) G3 (Bethesda) 11:
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Differentiation, Endocrine Cells, Eye Proteins, Gene Expression Regulation, Developmental, Homeodomain Proteins, Mice, PAX6 Transcription Factor, RNA, RNA Splicing, Repressor Proteins, Transcription Factors
Added September 24, 2021
2 Communities
3 Members
0 Resources
13 MeSH Terms
The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 α-enhancer activity.
Kim Y, Lim S, Ha T, Song YH, Sohn YI, Park DJ, Paik SS, Kim-Kaneyama JR, Song MR, Leung A, Levine EM, Kim IB, Goo YS, Lee SH, Kang KH, Kim JW
(2017) Elife 6:
MeSH Terms: Adaptation, Ocular, Animals, Cytoskeletal Proteins, DNA-Binding Proteins, Enhancer Elements, Genetic, Gene Expression Regulation, LIM Domain Proteins, LIM-Homeodomain Proteins, Mice, Mice, Knockout, PAX6 Transcription Factor, Retina, Transcription Factors
Added February 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells.
Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV
(2015) Development 142: 3637-48
MeSH Terms: Animals, Cell Transdifferentiation, Cellular Senescence, Diabetes Mellitus, Eye Proteins, Homeodomain Proteins, Humans, Hyperplasia, Insulin-Secreting Cells, Mice, PAX6 Transcription Factor, Paired Box Transcription Factors, Repressor Proteins, Somatostatin-Secreting Cells, Transcription Factors
Added December 28, 2015
0 Communities
3 Members
0 Resources
15 MeSH Terms
DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction.
Neely MD, Litt MJ, Tidball AM, Li GG, Aboud AA, Hopkins CR, Chamberlin R, Hong CC, Ess KC, Bowman AB
(2012) ACS Chem Neurosci 3: 482-91
MeSH Terms: Adult, Animals, Bone Morphogenetic Proteins, Carrier Proteins, Child, Eye Proteins, Female, Gene Expression Regulation, Homeodomain Proteins, Humans, Induced Pluripotent Stem Cells, Male, Mice, Middle Aged, Neural Inhibition, Neural Stem Cells, Neurogenesis, Neurons, PAX6 Transcription Factor, Paired Box Transcription Factors, Pyrazoles, Quinolines, Repressor Proteins, SOXB1 Transcription Factors, Stem Cells
Added August 25, 2013
3 Communities
4 Members
0 Resources
25 MeSH Terms
Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.
Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R
(2010) Mol Cell Biol 30: 4234-44
MeSH Terms: 5' Flanking Region, Animals, Base Sequence, Basic Helix-Loop-Helix Transcription Factors, Cells, Cultured, Eye Proteins, Glucose, Homeodomain Proteins, Humans, Insulin-Secreting Cells, Maf Transcription Factors, Large, Mice, Mice, Transgenic, Molecular Sequence Data, Mutation, Nerve Tissue Proteins, PAX6 Transcription Factor, Paired Box Transcription Factors, Protein Binding, Regulatory Sequences, Nucleic Acid, Repressor Proteins, Transcription, Genetic
Added December 5, 2013
2 Communities
1 Members
0 Resources
22 MeSH Terms
Genetic determinants of pancreatic epsilon-cell development.
Heller RS, Jenny M, Collombat P, Mansouri A, Tomasetto C, Madsen OD, Mellitzer G, Gradwohl G, Serup P
(2005) Dev Biol 286: 217-24
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Eye Proteins, Gene Expression Regulation, Developmental, Ghrelin, Glucagon, Green Fluorescent Proteins, Homeodomain Proteins, Islets of Langerhans, Mice, Mice, Mutant Strains, Mice, Transgenic, Nerve Tissue Proteins, PAX6 Transcription Factor, Paired Box Transcription Factors, Peptide Hormones, Recombinant Proteins, Repressor Proteins, Transcription Factors
Added October 30, 2012
0 Communities
0 Members
1 Resources
19 MeSH Terms
Molecular profiling indicates avian branchiomotor nuclei invade the hindbrain alar plate.
Ju MJ, Aroca P, Luo J, Puelles L, Redies C
(2004) Neuroscience 128: 785-96
MeSH Terms: Animals, Body Patterning, Cadherins, Chick Embryo, Eye Proteins, Gene Expression Regulation, Developmental, Hedgehog Proteins, Homeobox Protein Nkx-2.2, Homeodomain Proteins, Immunohistochemistry, In Situ Hybridization, Interferon Type I, Metalloproteins, Neurons, Nuclear Proteins, PAX6 Transcription Factor, PAX7 Transcription Factor, Paired Box Transcription Factors, Pregnancy Proteins, RNA, Messenger, Repressor Proteins, Reverse Transcriptase Polymerase Chain Reaction, Rhombencephalon, Spinal Cord, Trans-Activators, Transcription Factors, Zebrafish Proteins
Added November 5, 2010
0 Communities
0 Members
1 Resources
27 MeSH Terms
Differential regulation of islet-specific glucose-6-phosphatase catalytic subunit-related protein gene transcription by Pax-6 and Pdx-1.
Martin CC, Oeser JK, O'Brien RM
(2004) J Biol Chem 279: 34277-89
MeSH Terms: Amino Acid Motifs, Animals, Base Sequence, Binding Sites, Catalytic Domain, Cell Nucleus, Cells, Cultured, Chloramphenicol O-Acetyltransferase, Chromatin, DNA, Diabetes Mellitus, Experimental, Disease Models, Animal, Dose-Response Relationship, Drug, Electrophoresis, Polyacrylamide Gel, Eye Proteins, Gene Expression Regulation, Enzymologic, Glucose-6-Phosphatase, Homeodomain Proteins, Islets of Langerhans, Luciferases, Methylation, Mice, Molecular Sequence Data, Mutagenesis, Site-Directed, Mutation, Oligonucleotides, PAX6 Transcription Factor, Paired Box Transcription Factors, Plasmids, Polymerase Chain Reaction, Precipitin Tests, Promoter Regions, Genetic, Protein Binding, Protein Structure, Tertiary, Rats, Repressor Proteins, Salts, Subcellular Fractions, Trans-Activators, Transcription, Genetic
Added July 30, 2015
0 Communities
0 Members
1 Resources
40 MeSH Terms
The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity.
Heller RS, Stoffers DA, Liu A, Schedl A, Crenshaw EB, Madsen OD, Serup P
(2004) Dev Biol 268: 123-34
MeSH Terms: Animals, DNA-Binding Proteins, Eye Proteins, Glucagon, Homeobox Protein Nkx-2.2, Homeodomain Proteins, Immunohistochemistry, Mice, Mice, Knockout, Mice, Mutant Strains, Mice, Transgenic, Nerve Tissue Proteins, Nuclear Proteins, PAX6 Transcription Factor, POU Domain Factors, Paired Box Transcription Factors, Pancreas, Repressor Proteins, Transcription Factors
Added June 21, 2005
0 Communities
0 Members
2 Resources
19 MeSH Terms
Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2.
Cissell MA, Zhao L, Sussel L, Henderson E, Stein R
(2003) J Biol Chem 278: 751-6
MeSH Terms: Amyloid, Animals, Basic Helix-Loop-Helix Transcription Factors, Binding Sites, Cells, Cultured, DNA-Binding Proteins, Eye Proteins, Gene Expression Regulation, Glucose Transporter Type 2, Homeobox Protein Nkx-2.2, Homeodomain Proteins, Insulin, Islet Amyloid Polypeptide, Islets of Langerhans, Mice, Monosaccharide Transport Proteins, PAX6 Transcription Factor, Paired Box Transcription Factors, Rats, Repressor Proteins, Trans-Activators, Transcription Factors, Zebrafish Proteins
Added December 10, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms