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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 11

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Isolating the influences of fluid dynamics on selectin-mediated particle rolling at venular junctional regions.
Jung JJ, Grayson KA, King MR, Lamkin-Kennard KA
(2018) Microvasc Res 118: 144-154
MeSH Terms: Animals, Cell Adhesion, Humans, Hydrodynamics, Inflammation, Leukocyte Rolling, Leukocytes, Lewis X Antigen, Microspheres, Models, Cardiovascular, P-Selectin, Sialyl Lewis X Antigen, Signal Transduction, Venules
Added April 15, 2019
0 Communities
1 Members
0 Resources
14 MeSH Terms
Left Ventricular Function Across the Spectrum of Body Mass Index in African Americans: The Jackson Heart Study.
Patel VG, Gupta DK, Terry JG, Kabagambe EK, Wang TJ, Correa A, Griswold M, Taylor H, Carr JJ
(2017) JACC Heart Fail 5: 182-190
MeSH Terms: African Americans, Aged, Body Mass Index, C-Reactive Protein, Cohort Studies, E-Selectin, Female, Humans, Inflammation, Insulin Resistance, Intra-Abdominal Fat, Linear Models, Magnetic Resonance Imaging, Magnetic Resonance Imaging, Cine, Male, Middle Aged, Multidetector Computed Tomography, Multivariate Analysis, Obesity, Overweight, P-Selectin, Stroke Volume, Ventricular Dysfunction, Left, Ventricular Function, Left
Added March 4, 2017
0 Communities
3 Members
0 Resources
24 MeSH Terms
Inflammatory cytokine TSLP stimulates platelet secretion and potentiates platelet aggregation via a TSLPR-dependent PI3K/Akt signaling pathway.
Dong J, Dong J, Lin J, Wang B, He S, Wu C, Kushwaha KK, Mohabeer N, Su Y, Fang H, Huang K, Li D
(2015) Cell Physiol Biochem 35: 160-74
MeSH Terms: Androstadienes, Animals, Blood Platelets, Carotid Artery Thrombosis, Chlorides, Chromones, Cytokines, Disease Models, Animal, Ferric Compounds, Humans, Immunoglobulins, Mice, Mice, Inbred C57BL, Mice, Knockout, Morpholines, P-Selectin, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Phosphorylation, Platelet Activation, Platelet Aggregation, Platelet Glycoprotein GPIIb-IIIa Complex, Proto-Oncogene Proteins c-akt, Receptors, Cytokine, Signal Transduction, Wortmannin
Added January 20, 2015
0 Communities
1 Members
0 Resources
26 MeSH Terms
P-selectin 1087G/A polymorphism is associated with neuropsychological test performance in older adults with cardiovascular disease.
Gunstad J, Benitez A, Hoth KF, Spitznagel MB, McCaffery J, McGeary J, Kakos LS, Poppas A, Paul RH, Jefferson AL, Sweet LH, Cohen RA
(2009) Stroke 40: 2969-72
MeSH Terms: Adult, Aged, Aged, 80 and over, Alleles, C-Reactive Protein, Cardiovascular Diseases, Coronary Artery Bypass, Female, Humans, Male, Middle Aged, Neuropsychological Tests, P-Selectin, Polymorphism, Single Nucleotide
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Radiation-guided P-selectin antibody targeted to lung cancer.
Hariri G, Zhang Y, Fu A, Han Z, Brechbiel M, Tantawy MN, Peterson TE, Mernaugh R, Hallahan D
(2008) Ann Biomed Eng 36: 821-30
MeSH Terms: Animals, Antibodies, Neoplasm, Cell Line, Tumor, Dose-Response Relationship, Radiation, Lung Neoplasms, Male, Mice, Mice, Nude, P-Selectin, Radiation Dosage, Radionuclide Imaging, Radiotherapy
Added May 30, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Adenosine receptor-mediated adhesion of endothelial progenitors to cardiac microvascular endothelial cells.
Ryzhov S, Solenkova NV, Goldstein AE, Lamparter M, Fleenor T, Young PP, Greelish JP, Byrne JG, Vaughan DE, Biaggioni I, Hatzopoulos AK, Feoktistov I
(2008) Circ Res 102: 356-63
MeSH Terms: Adenosine, Adenosine A1 Receptor Agonists, Adenosine A2 Receptor Agonists, Animals, Cell Adhesion, Cells, Cultured, Endothelial Cells, Endothelium, Vascular, Membrane Glycoproteins, Mice, Myocardial Ischemia, Myocardium, Neovascularization, Physiologic, P-Selectin, Receptor, Adenosine A1, Receptor, Adenosine A2B, Stem Cell Transplantation, Stem Cells, Vasodilator Agents
Added December 10, 2013
1 Communities
3 Members
0 Resources
19 MeSH Terms
Association of multiple inflammatory markers with carotid intimal medial thickness and stenosis (from the Framingham Heart Study).
Thakore AH, Guo CY, Larson MG, Corey D, Wang TJ, Vasan RS, D'Agostino RB, Lipinska I, Keaney JF, Benjamin EJ, O'Donnell CJ
(2007) Am J Cardiol 99: 1598-602
MeSH Terms: Aged, Biomarkers, C-Reactive Protein, CD40 Ligand, Carotid Artery, Common, Carotid Stenosis, Chemokine CCL2, Confounding Factors, Epidemiologic, Female, Humans, Inflammation Mediators, Intercellular Adhesion Molecule-1, Interleukin-6, Male, Middle Aged, P-Selectin, Predictive Value of Tests, Tunica Intima, Tunica Media, Ultrasonography
Added April 15, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP.
Cleator JH, Zhu WQ, Vaughan DE, Hamm HE
(2006) Blood 107: 2736-44
MeSH Terms: Calcium Signaling, Cell Line, Cyclic AMP, Endothelium, Vascular, Exocytosis, Humans, Kinetics, P-Selectin, Peptide Hydrolases, Protein Transport, Receptor, PAR-1, Receptor, PAR-2, Receptors, Cell Surface, Signal Transduction, Thrombin, Umbilical Veins, von Willebrand Factor
Show Abstract · Added January 20, 2015
Thrombin-mediated endothelial-cell release of von Willebrand factor (VWF) and P-selectin functionally links protease-activated receptors (PARs) to thrombosis and inflammation. VWF release can be stimulated by both Ca2+ and cAMP, and, although both VWF and P-selectin are found in Weibel-Palade bodies (WPBs), we found that their release could be differentially regulated. In these studies, human umbilical vein endothelial cells stimulated with cAMP or PAR2-AP led to a delayed release of VWF and significantly less P-selectin release compared with histamine, thrombin, or PAR1-AP. Dose-response studies revealed that PAR2-AP was significantly less efficacious in promoting the release of P-selectin compared with VWF. PAR2-AP-induced robust stimulation of intracellular Ca2+ coupled with a significantly greater inhibitory effect of calcium chelation on release of VWF compared with cell-surface expression of P-selectin, suggests an additional Ca2+-independent pathway involved in release of P-selectin. PAR2-AP failed to increase global cAMP levels; however, inhibition of protein kinase A led to a significant attenuation of PAR2-AP-mediated release of VWF. Confocal microscopy studies revealed that PAR2 and forskolin caused preferential release of a population of Weibel-Palade bodies (WPBs) consisting of only VWF. Thus, WPBs are pharmacologically and morphologically heterogeneous, and distinct granule populations are susceptible to differential regulation.
0 Communities
1 Members
0 Resources
17 MeSH Terms
Experimental autoimmune anti-glomerular basement membrane glomerulonephritis: a protective role for IFN-gamma.
Kitching AR, Turner AL, Semple T, Li M, Edgtton KL, Wilson GR, Timoshanko JR, Hudson BG, Holdsworth SR
(2004) J Am Soc Nephrol 15: 1764-74
MeSH Terms: Animals, Anti-Glomerular Basement Membrane Disease, Apoptosis, Autoimmune Diseases, CD4-Positive T-Lymphocytes, Cell Adhesion, Cell Division, Creatinine, Dimerization, Enzyme-Linked Immunosorbent Assay, Glomerulonephritis, Hypersensitivity, Delayed, Immunoglobulin G, Immunohistochemistry, Intercellular Adhesion Molecule-1, Interferon-gamma, Interleukin-12, Leukocytes, Lupus Vulgaris, Mice, Mice, Inbred C57BL, Mice, Transgenic, Microscopy, Fluorescence, P-Selectin, Proteinuria, Time Factors
Added December 10, 2013
1 Communities
1 Members
0 Resources
26 MeSH Terms
Epstein-Barr virus recombinant lacking expression of glycoprotein gp150 infects B cells normally but is enhanced for infection of epithelial cells.
Borza CM, Hutt-Fletcher LM
(1998) J Virol 72: 7577-82
MeSH Terms: B-Lymphocytes, Cell Line, E-Selectin, Epithelial Cells, Glycoproteins, Herpesvirus 4, Human, Humans, Metalloendopeptidases, Open Reading Frames, P-Selectin, Plasmids, Recombination, Genetic, Viral Proteins
Added August 22, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms