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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 578

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Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells.
Rahim M, Nakhe AY, Banerjee DR, Overway EM, Bosma KJ, Rosch JC, Oeser JK, Wang B, Lippmann ES, Jacobson DA, O'Brien RM, Young JD
(2022) J Biol Chem 298: 101729
MeSH Terms: Animals, Blood Glucose, Diabetes Mellitus, Type 2, Genome-Wide Association Study, Glucose, Glucose-6-Phosphatase, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice, Mice, Knockout, Oxidation-Reduction
Added June 27, 2022
0 Communities
1 Members
0 Resources
MeSH Terms
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells.
Wang Y, Yen FS, Zhu XG, Timson RC, Weber R, Xing C, Liu Y, Allwein B, Luo H, Yeh HW, Heissel S, Unlu G, Gamazon ER, Kharas MG, Hite R, Birsoy K
(2021) Nature 599: 136-140
MeSH Terms: Animals, Biological Transport, Cell Proliferation, Cells, Cultured, Erythropoiesis, Glutathione, Homeostasis, Humans, Iron-Sulfur Proteins, Mice, Mitochondria, Mitochondrial Membrane Transport Proteins, Oxidation-Reduction, Proteome, Proteomics
Added October 29, 2021
0 Communities
1 Members
0 Resources
15 MeSH Terms
Gut Epithelial Metabolism as a Key Driver of Intestinal Dysbiosis Associated with Noncommunicable Diseases.
Shelton CD, Byndloss MX
(2020) Infect Immun 88:
MeSH Terms: Animals, Colon, Disease Susceptibility, Dysbiosis, Energy Metabolism, Enterobacteriaceae, Gastrointestinal Microbiome, Humans, Intestinal Mucosa, Noncommunicable Diseases, Obesity, Oxidation-Reduction, Risk Assessment, Risk Factors
Added March 30, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
Cold exposure induces dynamic, heterogeneous alterations in human brown adipose tissue lipid content.
Coolbaugh CL, Damon BM, Bush EC, Welch EB, Towse TF
(2019) Sci Rep 9: 13600
MeSH Terms: Adipose Tissue, Brown, Adult, Cold Temperature, Fatty Acids, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Oxidation-Reduction, Young Adult
Added March 3, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Human cytochrome P450 enzymes bind drugs and other substrates mainly through conformational-selection modes.
Guengerich FP, Wilkey CJ, Phan TTN
(2019) J Biol Chem 294: 10928-10941
MeSH Terms: Catalysis, Cytochrome P-450 CYP2D6, Cytochrome P-450 CYP2E1, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System, Humans, Kinetics, Lauric Acids, Ligands, Molecular Conformation, Oxidation-Reduction, Palmitic Acid, Protein Binding, Protein Conformation, Spiro Compounds, Substrate Specificity
Added March 3, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Oxidation of Flavone, 5-Hydroxyflavone, and 5,7-Dihydroxyflavone to Mono-, Di-, and Tri-Hydroxyflavones by Human Cytochrome P450 Enzymes.
Nagayoshi H, Murayama N, Kakimoto K, Tsujino M, Takenaka S, Katahira J, Lim YR, Kim D, Yamazaki H, Komori M, Guengerich FP, Shimada T
(2019) Chem Res Toxicol 32: 1268-1280
MeSH Terms: Cytochrome P-450 Enzyme System, Flavones, Flavonoids, Humans, Molecular Structure, Oxidation-Reduction
Added March 3, 2020
0 Communities
1 Members
0 Resources
6 MeSH Terms
Isotopic tagging of oxidized and reduced cysteines (iTORC) for detecting and quantifying sulfenic acids, disulfides, and free thiols in cells.
Albertolle ME, Glass SM, Trefts E, Guengerich FP
(2019) J Biol Chem 294: 6522-6530
MeSH Terms: Animals, Benzothiadiazines, Cysteine, Hepatocytes, Isotope Labeling, Male, Mice, Oxidation-Reduction, Sulfenic Acids
Added March 26, 2019
0 Communities
1 Members
0 Resources
9 MeSH Terms
Dysregulated transmethylation leading to hepatocellular carcinoma compromises redox homeostasis and glucose formation.
Hughey CC, James FD, Wang Z, Goelzer M, Wasserman DH
(2019) Mol Metab 23: 1-13
MeSH Terms: Animals, Carcinoma, Hepatocellular, DNA Methylation, Fatty Liver, Gene Knockout Techniques, Gluconeogenesis, Glucose, Glycine N-Methyltransferase, Homeostasis, Liver, Liver Neoplasms, Male, Methionine, Mice, Mice, Knockout, NAD, Oxidation-Reduction
Added March 26, 2019
1 Communities
0 Members
0 Resources
17 MeSH Terms
Glutamine-451 Confers Sensitivity to Oxidative Inhibition and Heme-Thiolate Sulfenylation of Cytochrome P450 4B1.
Albertolle ME, Song HD, Wilkey CJ, Segrest JP, Guengerich FP
(2019) Chem Res Toxicol 32: 484-492
MeSH Terms: Animals, Aryl Hydrocarbon Hydroxylases, Glutamine, Heme, Molecular Dynamics Simulation, Mutagenesis, Site-Directed, Oxidation-Reduction, Rabbits, Sulfenic Acids, Sulfhydryl Compounds
Added March 26, 2019
0 Communities
1 Members
0 Resources
10 MeSH Terms
Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K.
Elajaili HB, Hernandez-Lagunas L, Ranguelova K, Dikalov S, Nozik-Grayck E
(2019) J Vis Exp :
MeSH Terms: Animals, Antimycin A, Bleomycin, Bronchoalveolar Lavage Fluid, Cattle, Cell Compartmentation, Electron Spin Resonance Spectroscopy, Lung, Mice, Mitochondria, Oxidation-Reduction, RAW 264.7 Cells, Superoxides, Temperature
Added March 26, 2019
0 Communities
1 Members
0 Resources
14 MeSH Terms