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Results: 1 to 4 of 4

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Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic β-Cells.
Osipovich AB, Stancill JS, Cartailler JP, Dudek KD, Magnuson MA
(2020) Diabetes 69: 1476-1491
MeSH Terms: Animals, Calcium, Cells, Cultured, Diet, High-Fat, Female, Gene Expression Regulation, Glucose, Insulin-Secreting Cells, Male, Mice, Mice, Inbred C57BL, Mitochondria, Overnutrition, Sex Characteristics, Transcriptome
Added April 28, 2020
2 Communities
3 Members
0 Resources
15 MeSH Terms
FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation.
Li M, Page-McCaw P, Chen W
(2016) Diabetes 65: 96-109
MeSH Terms: Animals, Animals, Genetically Modified, Cell Differentiation, Cell Line, Tumor, Endoplasmic Reticulum Stress, Fibroblast Growth Factor 1, Flow Cytometry, Humans, Insulin-Secreting Cells, Overnutrition, RNA, Messenger, Rats, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Zebrafish, Zebrafish Proteins
Added February 15, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
Skeletal muscle insulin resistance in zebrafish induces alterations in β-cell number and glucose tolerance in an age- and diet-dependent manner.
Maddison LA, Joest KE, Kammeyer RM, Chen W
(2015) Am J Physiol Endocrinol Metab 308: E662-9
MeSH Terms: Aging, Animals, Animals, Genetically Modified, Biological Transport, Cell Count, Disease Progression, Glucose, Glucose Intolerance, Green Fluorescent Proteins, Hyperglycemia, Insulin, Insulin Resistance, Insulin-Like Growth Factor I, Insulin-Secreting Cells, Luminescent Proteins, Muscle, Skeletal, Overnutrition, Receptor, IGF Type 1, Recombinant Fusion Proteins, Zebrafish, Zebrafish Proteins
Added February 12, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Overnutrition induces β-cell differentiation through prolonged activation of β-cells in zebrafish larvae.
Li M, Maddison LA, Page-McCaw P, Chen W
(2014) Am J Physiol Endocrinol Metab 306: E799-807
MeSH Terms: Animals, Animals, Genetically Modified, Calcium Channels, L-Type, Cell Count, Cell Differentiation, Disease Models, Animal, Embryo, Nonmammalian, Glucokinase, Insulin-Secreting Cells, KATP Channels, Larva, Membrane Potentials, Overnutrition, Potassium Channels, Inwardly Rectifying, Zebrafish
Added April 24, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms