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Results: 1 to 10 of 16

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Staphylococcus aureus Osteomyelitis: Bone, Bugs, and Surgery.
Urish KL, Cassat JE
(2020) Infect Immun 88:
MeSH Terms: Animals, Biopsy, Combined Modality Therapy, Disease Management, Disease Susceptibility, Humans, Osteomyelitis, Research, Staphylococcal Infections, Staphylococcus aureus, Symptom Assessment
Added March 25, 2020
0 Communities
1 Members
0 Resources
11 MeSH Terms
Staphylococcus aureus Infects Osteoclasts and Replicates Intracellularly.
Krauss JL, Roper PM, Ballard A, Shih CC, Fitzpatrick JAJ, Cassat JE, Ng PY, Pavlos NJ, Veis DJ
(2019) mBio 10:
MeSH Terms: Animals, Bacterial Proteins, Cell Differentiation, Cells, Cultured, Female, Macrophages, Male, Mice, Osteoblasts, Osteoclasts, Osteomyelitis, Phagosomes, RANK Ligand, Staphylococcus aureus
Added March 25, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
A Clinical Review of Diabetic Foot Infections.
Chastain CA, Klopfenstein N, Serezani CH, Aronoff DM
(2019) Clin Podiatr Med Surg 36: 381-395
MeSH Terms: Anti-Bacterial Agents, Debridement, Diabetic Foot, Drug Resistance, Microbial, Humans, Infectious Disease Medicine, Osteomyelitis, Risk Factors, Wound Healing
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis.
Putnam NE, Fulbright LE, Curry JM, Ford CA, Petronglo JR, Hendrix AS, Cassat JE
(2019) PLoS Pathog 15: e1007744
MeSH Terms: Animals, Bone Resorption, Cell Differentiation, Cells, Cultured, Female, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Differentiation Factor 88, Osteoclasts, Osteomyelitis, Receptors, Interleukin-1 Type I, Signal Transduction, Staphylococcal Infections, Staphylococcus aureus
Added April 15, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
Advances in the local and targeted delivery of anti-infective agents for management of osteomyelitis.
Ford CA, Cassat JE
(2017) Expert Rev Anti Infect Ther 15: 851-860
MeSH Terms: Absorbable Implants, Anti-Infective Agents, Copper, Debridement, Disease Management, Drug Delivery Systems, Humans, Microspheres, Osteomyelitis, Polyurethanes, Silver, Staphylococcal Infections, Staphylococcus aureus, Tissue Scaffolds
Added April 3, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
Staphylococcus aureus protein A enhances osteoclastogenesis via TNFR1 and EGFR signaling.
Mendoza Bertelli A, Delpino MV, Lattar S, Giai C, Llana MN, Sanjuan N, Cassat JE, Sordelli D, Gómez MI
(2016) Biochim Biophys Acta 1862: 1975-83
MeSH Terms: Animals, Cell Differentiation, ErbB Receptors, Humans, Mice, Mice, Inbred BALB C, Mice, Knockout, Osteoclasts, Osteomyelitis, RANK Ligand, Receptors, Tumor Necrosis Factor, Type I, Staphylococcal Infections, Staphylococcal Protein A, Staphylococcus aureus, Tumor Necrosis Factor-alpha
Added April 3, 2018
0 Communities
1 Members
0 Resources
15 MeSH Terms
Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus.
Loughran AJ, Gaddy D, Beenken KE, Meeker DG, Morello R, Zhao H, Byrum SD, Tackett AJ, Cassat JE, Smeltzer MS
(2016) Infect Immun 84: 2586-94
MeSH Terms: Animals, Bacterial Proteins, Gene Expression Regulation, Bacterial, Mice, Mice, Inbred C57BL, Mutation, Operon, Osteoblasts, Osteoclasts, Osteomyelitis, Proteomics, Staphylococcal Infections, Staphylococcus aureus, Virulence, Virulence Factors
Added April 3, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Repurposing the Nonsteroidal Anti-inflammatory Drug Diflunisal as an Osteoprotective, Antivirulence Therapy for Staphylococcus aureus Osteomyelitis.
Hendrix AS, Spoonmore TJ, Wilde AD, Putnam NE, Hammer ND, Snyder DJ, Guelcher SA, Skaar EP, Cassat JE
(2016) Antimicrob Agents Chemother 60: 5322-30
MeSH Terms: Animals, Anti-Bacterial Agents, Anti-Inflammatory Agents, Non-Steroidal, Bacterial Proteins, Bone Density Conservation Agents, Cell Survival, Delayed-Action Preparations, Diflunisal, Drug Repositioning, Female, Gene Expression, Humans, Mice, Mice, Inbred C57BL, Osteoblasts, Osteomyelitis, Primary Cell Culture, Staphylococcal Infections, Staphylococcus aureus, Trans-Activators, Treatment Outcome
Added April 8, 2017
0 Communities
3 Members
0 Resources
21 MeSH Terms
Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection.
Wilde AD, Snyder DJ, Putnam NE, Valentino MD, Hammer ND, Lonergan ZR, Hinger SA, Aysanoa EE, Blanchard C, Dunman PM, Wasserman GA, Chen J, Shopsin B, Gilmore MS, Skaar EP, Cassat JE
(2015) PLoS Pathog 11: e1005341
MeSH Terms: Animals, Cell Hypoxia, Cell Line, DNA Transposable Elements, Disease Models, Animal, Female, Gene Expression Regulation, Bacterial, Genes, Viral, Host-Pathogen Interactions, Humans, Mice, Mice, Inbred C57BL, Oligonucleotide Array Sequence Analysis, Osteomyelitis, Quorum Sensing, Reverse Transcriptase Polymerase Chain Reaction, Staphylococcal Infections, Staphylococcus aureus, Virulence, Virulence Factors
Added February 8, 2016
0 Communities
2 Members
0 Resources
20 MeSH Terms
Inter- and intraspecies metabolite exchange promotes virulence of antibiotic-resistant Staphylococcus aureus.
Hammer ND, Cassat JE, Noto MJ, Lojek LJ, Chadha AD, Schmitz JE, Creech CB, Skaar EP
(2014) Cell Host Microbe 16: 531-7
MeSH Terms: Animals, Coinfection, Disease Models, Animal, Drug Resistance, Bacterial, Humans, Mice, Inbred C57BL, Microbial Interactions, Mutation, Osteomyelitis, Staphylococcal Infections, Staphylococcus aureus, Virulence
Added January 20, 2015
0 Communities
2 Members
0 Resources
12 MeSH Terms