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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 21

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Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice.
Gilchuk IM, Bangaru S, Gilchuk P, Irving RP, Kose N, Bombardi RG, Thornburg NJ, Creech CB, Edwards KM, Li S, Turner HL, Yu W, Zhu X, Wilson IA, Ward AB, Crowe JE
(2019) Cell Host Microbe 26: 715-728.e8
MeSH Terms: Animals, Antibodies, Heterophile, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Birds, Epitopes, Humans, Influenza A Virus, H7N9 Subtype, Influenza Vaccines, Influenza in Birds, Influenza, Human, Mice, Neuraminidase, Orthomyxoviridae Infections, Pre-Exposure Prophylaxis, Vaccination, Vaccines, Inactivated, Viral Proteins, Virus Release
Added March 31, 2020
0 Communities
1 Members
0 Resources
20 MeSH Terms
Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Zhu X, Turner HL, Lang S, McBride R, Bangaru S, Gilchuk IM, Yu W, Paulson JC, Crowe JE, Ward AB, Wilson IA
(2019) Cell Host Microbe 26: 729-738.e4
MeSH Terms: Animals, Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Antiviral Agents, Cryoelectron Microscopy, Epitopes, Humans, Influenza A Virus, H7N9 Subtype, Influenza Vaccines, Neuraminidase, Orthomyxoviridae Infections, Viral Proteins
Added March 31, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Control of antiviral innate immune response by protein geranylgeranylation.
Yang S, Harding AT, Sweeney C, Miao D, Swan G, Zhou C, Jiang Z, Fitzgerald KA, Hammer G, Bergo MO, Kroh HK, Lacy DB, Sun C, Glogauer M, Que LG, Heaton NS, Wang D
(2019) Sci Adv 5: eaav7999
MeSH Terms: Adaptor Proteins, Signal Transducing, Alkyl and Aryl Transferases, Animals, Endoplasmic Reticulum, Female, Humans, Immunity, Innate, Macrophages, Alveolar, Male, Mice, Knockout, Neuropeptides, Orthomyxoviridae Infections, Protein Prenylation, Receptor-Interacting Protein Serine-Threonine Kinases, Tripartite Motif Proteins, Ubiquitin-Protein Ligases, rac GTP-Binding Proteins, rac1 GTP-Binding Protein
Added March 24, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Influenza viruses with receptor-binding N1 neuraminidases occur sporadically in several lineages and show no attenuation in cell culture or mice.
Hooper KA, Crowe JE, Bloom JD
(2015) J Virol 89: 3737-45
MeSH Terms: Animals, Cell Line, Disease Models, Animal, Dogs, Female, Humans, Influenza A Virus, H1N1 Subtype, Influenza A Virus, H5N1 Subtype, Mice, Inbred BALB C, Mutant Proteins, Mutation, Missense, Neuraminidase, Orthomyxoviridae Infections, Protein Binding, Receptors, Virus, Reverse Genetics, Viral Proteins, Virus Attachment, Virus Cultivation
Added February 2, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
The immune profile associated with acute allergic asthma accelerates clearance of influenza virus.
Samarasinghe AE, Woolard SN, Boyd KL, Hoselton SA, Schuh JM, McCullers JA
(2014) Immunol Cell Biol 92: 449-59
MeSH Terms: Acute Disease, Animals, Asthma, Chronic Disease, Disease Models, Animal, Female, Host-Pathogen Interactions, Humans, Influenza A Virus, H1N1 Subtype, Influenza, Human, Interferons, Mice, Orthomyxoviridae Infections, Respiratory Mucosa
Added March 20, 2014
1 Communities
1 Members
0 Resources
14 MeSH Terms
A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase.
Hayakawa M, Toda N, Carrillo N, Thornburg NJ, Crowe JE, Barbas CF
(2012) Chembiochem 13: 2191-5
MeSH Terms: Animals, Antibodies, Monoclonal, Antiviral Agents, Click Chemistry, Fructose-Bisphosphate Aldolase, Humans, Immunoconjugates, Influenza A virus, Influenza, Human, Mice, Models, Molecular, Neuraminidase, Orthomyxoviridae Infections, Zanamivir
Added October 28, 2012
0 Communities
1 Members
0 Resources
14 MeSH Terms
Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses.
Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Albrecht R, Blum DL, Ramos I, Fernandez-Sesma A, Edwards KM, García-Sastre A, Basler CF, Crowe JE
(2012) J Virol 86: 6334-40
MeSH Terms: Adult, Animals, Antibodies, Monoclonal, Antibodies, Viral, Chick Embryo, Disease Models, Animal, Female, Hemagglutinin Glycoproteins, Influenza Virus, Humans, Influenza A Virus, H2N2 Subtype, Influenza A Virus, H3N2 Subtype, Influenza, Human, Mice, Mice, Inbred BALB C, Middle Aged, Molecular Sequence Data, Mutation, Missense, Orthomyxoviridae Infections, RNA, Viral, Sequence Analysis, DNA, Survival Analysis
Added August 6, 2012
0 Communities
1 Members
0 Resources
21 MeSH Terms
Unveiling the burden of influenza-associated pneumococcal pneumonia.
Grijalva CG, Griffin MR
(2012) J Infect Dis 205: 355-7
MeSH Terms: Animals, Bronchopneumonia, Carrier State, Female, Ferrets, Host-Pathogen Interactions, Humans, Influenza A virus, Male, Metapneumovirus, Orthomyxoviridae, Orthomyxoviridae Infections, Paramyxoviridae Infections, Platelet Membrane Glycoproteins, Pneumococcal Infections, Pneumococcal Vaccines, Pneumonia, Pneumococcal, Pneumonia, Viral, Population Surveillance, Receptors, Cell Surface, Receptors, G-Protein-Coupled, Streptococcus pneumoniae
Added July 27, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Immunopathogenic and antibacterial effects of H3N2 influenza A virus PB1-F2 map to amino acid residues 62, 75, 79, and 82.
Alymova IV, Green AM, van de Velde N, McAuley JL, Boyd KL, Ghoneim HE, McCullers JA
(2011) J Virol 85: 12324-33
MeSH Terms: Amino Acid Sequence, Animals, Cells, Cultured, Chemokines, Cytokines, Dogs, Female, Humans, Influenza A Virus, H3N2 Subtype, Kidney, Mice, Mice, Inbred BALB C, Molecular Sequence Data, Mutagenesis, Site-Directed, Mutation, Orthomyxoviridae Infections, Peptide Fragments, Pneumococcal Infections, Pneumonia, Sequence Homology, Amino Acid, Streptococcus pneumoniae, Viral Proteins, Virus Replication
Added March 20, 2014
1 Communities
1 Members
0 Resources
23 MeSH Terms
Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza.
Karlström A, Heston SM, Boyd KL, Tuomanen EI, McCullers JA
(2011) J Infect Dis 204: 1358-66
MeSH Terms: Animals, Anti-Bacterial Agents, Female, Immunologic Factors, Lung, Macrolides, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Neutrophils, Orthomyxoviridae Infections, Pneumonia, Pneumococcal, Streptococcus pneumoniae, Toll-Like Receptor 2, Treatment Outcome, beta-Lactams
Added March 20, 2014
1 Communities
1 Members
0 Resources
17 MeSH Terms